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    Wythe County, VA Commercial Real Estate for Lease

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    Richmond, VA Virginia Beach, VA Alexandria, VA
    7 results
    Dominant Regional Retail Center Space
    Contact for pricing
    5,021 SF

    Dominant Regional Retail Center Space

    215-345 Commonwealth Dr, Wytheville, VA

    Regional retail center anchored by Walmart and Lowes.

    • Anchored by Walmart Supercenter and Lowes Home Improvement, driving significant customer traffic
    • Located at the busiest intersection in the area, off I‑81 (exit 70) and SR 21
    • High traffic counts: 31,000 VPD on I‑81 and 16,000 VPD on Hwy 21
    • Dominant regional retail center in Wytheville, VA, drawing from a 10‑mile radius
    • National tenants including Bealls, Dollar Tree, Petco, Pizza Hut and Subway
    Updated: Aug 4, 2025
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    Former Restaurant Space Available
    $216 SF/Yr
    6,064 SF

    Former Restaurant Space Available

    190 Lithia Rd, Wytheville, VA 24382

    Restaurant space for lease in high-traffic area.

    • High‑traffic location in the I‑81 / I‑77 Crossroads development corridor.
    • Large 6,064 SF building on 1.26 acres.
    • Favorable B zoning.
    • Wythe County Assessment of $1,312,800.
    • Former Bob Evans restaurant space.
    Updated: Feb 10, 2025
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    Retail Space in Lehy Plaza
    Contact for pricing
    18,900 SF

    Retail Space in Lehy Plaza

    Retail space available in Food Lion anchored Lehy Plaza.

    1370-1380 E Main St, Wytheville, VA
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    Retail Space in High-Traffic Center
    $26 SF/Yr

    Retail Space in High-Traffic Center

    End unit retail space in Starbucks-anchored center with high foot traffic.

    198 Commonwealth Dr, Wytheville, VA 24382
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    Renovated Shopping Center For Lease
    Contact for pricing
    1,385 SF

    Renovated Shopping Center For Lease

    99,745 SF renovated shopping center on 8.69 acres.

    205 Fairground Road, Wytheville, VA
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    Renovated Shopping Center For Lease
    Contact for pricing
    4,311 SF

    Renovated Shopping Center For Lease

    99,745 SF renovated shopping center on 8.69 acres.

    880 E Main St, Wytheville, VA
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    Renovated Shopping Center Space Available
    Contact for pricing
    1,400 SF

    Renovated Shopping Center Space Available

    99,745 SF renovated shopping center on 8.69 acres.

    235 Fairground Rd, Wytheville, VA
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    Based on your search, we've compiled 43 Potential Opportunities for your consideration. Besides 7 Active listings in Wythe County, VA, we suggest exploring alternatives. Similar 36 Properties for Sales.

    Similar Spaces for Sale in Wythe County, VA

    Consider Similar Space for Sale. We found 36 Spaces matching your search parameters.

    Commercial Property in Wytheville, VA
    $250,000
    3,360 SF

    Commercial Property in Wytheville, VA

    Income-producing commercial property with established tenants in a prime location.

    1330 W Ridge Street, Wytheville, VA 24382
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    Sprawling Hobby Farm Near Wytheville
    $750,000
    40.20 Acres

    Sprawling Hobby Farm Near Wytheville

    40-acre hobby farm with home, outbuildings, and commercial potential.

    4502 Grayson Turnpike lot: 0, Crockett, VA 24323
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    21-Acre Wythe County Land
    $325,000
    21.53 Acres

    21-Acre Wythe County Land

    21-acre property with mountain views, utilities, and temporary home.

    388 Spraker Road lot: A, Crockett, VA 24323
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    Downtown Wytheville Multi-Purpose Commercial Building
    $399,000
    4,949 SF

    Downtown Wytheville Multi-Purpose Commercial Building

    Two-story commercial building with income potential in downtown Wytheville.

    195 S 1st Street, Wytheville, VA 24382
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    Wytheville Land Development Opportunity
    $169,900
    1.85 Acres

    Wytheville Land Development Opportunity

    1.847 acres in Wytheville, VA, zoned for diverse development.

    Peppers Ferry Road lot: 2, Wytheville, VA 24382
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    Commercial Lot in Wytheville, VA
    $199,000
    1.36 Acres

    Commercial Lot in Wytheville, VA

    Commercial lot with high visibility near I-81 and local amenities.

    1.36 AC N 4th St., Wytheville, VA 24382
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    Austinville Commercial Land For Sale
    $299,000
    3.83 Acres

    Austinville Commercial Land For Sale

    3.8-acre commercial land with high visibility and development potential.

    Fort Chiswell Road, Austinville, VA 24312
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    Ready-to-Develop Land with Utilities
    $199,500
    2,000 SF

    Ready-to-Develop Land with Utilities

    Investment property with utilities, outbuildings, and potential rental income.

    6 lots Owl Tree Lane lot: 0, Rural Retreat, VA 24368
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    Riverfront Acreage with Development Potential
    $219,500
    1.00 Acre

    Riverfront Acreage with Development Potential

    One-acre riverfront property ideal for development or recreational use.

    136 Lansworth Drive lot: 104-118, Austinville, VA 24312
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    Wytheville Commercial Property with Acreage
    $640,000
    6,000 SF

    Wytheville Commercial Property with Acreage

    Commercial property with building, doublewide, acreage, and mountain views.

    135 Envision Drive, Wytheville, VA 24382
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    Expansive Land Parcel in Wytheville
    $2,950,000
    87.66 Acres

    Expansive Land Parcel in Wytheville

    87+ acre parcel ideal for commercial or residential development.

    Community Blvd lot: 131, Wytheville, VA 24382
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    Industrial-Zoned Property in Wytheville, VA
    $299,000
    2.58 Acres

    Industrial-Zoned Property in Wytheville, VA

    2.58-acre industrial-zoned property near industrial park in Wytheville, VA.

    N 4th Street, Wytheville, VA 24382
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    Commercial Lot Near Interstate Exit
    $99,000
    39,630 SF

    Commercial Lot Near Interstate Exit

    Commercial land near I-81 exit with high traffic volume.

    Holston Road, Wytheville, VA 24382
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    Working Animal Farm For Sale
    $15,000,000
    65.80 Acres

    Working Animal Farm For Sale

    65.8-acre working animal farm with multiple homes and business potential.

    103 Archer Road, Max Meadows, VA 24360
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    Scenic Farmland & Recreational Land
    $559,500
    95.93 Acres

    Scenic Farmland & Recreational Land

    96+/- acres in Rural Retreat, VA with pasture and views.

    892 Ward Branch Rd lot: 0, Rural Retreat, VA 24368
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    63.4 Acres in Ivanhoe, VA
    $450,000
    63.40 Acres

    63.4 Acres in Ivanhoe, VA

    Cleared land ideal for livestock, development, or estate home.

    Ivanhoe Rd lot: 1-22, Ivanhoe, VA 24350
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    Wytheville Commercial Land For Sale
    $2,600,000
    35.00 Acres

    Wytheville Commercial Land For Sale

    35 acres of commercial land near the interstate.

    Stafford Umberger Drive, Wytheville, VA 24382
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    Wythe County, VA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Wythe County, VA with 7 listings featured on our commercial real estate exchange. The current inventory includes 6,064 square feet of properties with an estimated lease value of $216 SF/Yr.

    Estimated lease rates for Commercial real estate in Wythe County, VA begin at $216 SF/Yr, with an average of $216 SF/Yr and extend to $216 SF/Yr.
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