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    South Setauket, NY Commercial Real Estate for Lease

    16 results
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    Centereach Commercial Space for Rent
    $2,200 / Mo
    640 SF

    Centereach Commercial Space for Rent

    158 Holbrook Rd, Centereach, NY 11741

    640 sq ft commercial space on a high-visibility corner lot.

    • High‑visibility corner lot location on a busy main road.
    • Move‑in ready, professional 640 sq. ft. space with private entrance.
    • Lead‑plated room ideal for medical, dental, or radiology services.
    • Ample private parking in a multi‑space lot.
    • Wheelchair accessible throughout.
    Updated: Sep 27, 2025
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    Centereach Office Space For Rent
    $4,200 / Mo
    2,600 SF

    Centereach Office Space For Rent

    2450 Middle Country Rd, Centereach, NY 11720

    Second-floor office space in prime Centereach location, available furnished.

    • Prime location on Middle Country Rd in the heart of Centereach.
    • 2500 sq ft of 2nd‑floor office space.
    • Features 5 private offices, including one with a private bathroom.
    • Fully furnished with computers, phones, and office equipment.
    • Handicap accessible with stair lifts and a handicap‑accessible bathroom.
    Updated: Sep 26, 2025
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    Centereach Medical Office Space For Lease
    Contact for pricing
    5,600 SF

    Centereach Medical Office Space For Lease

    5,600 SF Medical Office - High Visibility

    2101 Middle Country Rd, Centereach, NY 11720
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    Centereach Square: Retail Opportunity
    Contact for pricing
    387,034 SF

    Centereach Square: Retail Opportunity

    High-traffic retail center, multiple spaces available.

    0 Centereach Mall, Centereach, NY 11720
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    Centereach Retail Space Available
    $22 SF/Yr
    1,600 SF

    Centereach Retail Space Available

    Retail space available for lease in Centereach, New York.

    115 Mark Tree Rd, Centereach, NY 11720
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    Centereach Retail Space Available
    Contact for pricing
    1,400 SF

    Centereach Retail Space Available

    Retail space for lease in Centereach Mall.

    191-243 Centereach Mall, Centereach, NY 11720
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    Centereach Retail Space Available
    Contact for pricing
    2,400 SF

    Centereach Retail Space Available

    Retail space for lease with high traffic volume.

    141-157 Centereach Mall, Centereach, NY 11720
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    Retail Space on Middle Country
    Contact for pricing
    5,000 SF

    Retail Space on Middle Country

    Retail space with high traffic and multiple access points.

    257 Middle Country Rd, Centereach, NY 11720
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    Retail Space Near Centereach Mall
    Contact for pricing
    18,500 SF

    Retail Space Near Centereach Mall

    Community strip center near Centereach Mall and Walmart.

    1930-1934 Middle Country Rd, Centereach, NY 11720
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    Retail Space in Centereach, NY
    $23 SF/Yr

    Retail Space in Centereach, NY

    2,000 sqft retail space available for lease.

    1787 Middle Country Rd, Centereach, NY 11720
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    Comfortable Apartment with Large Basement
    $1,900 / Mo

    Comfortable Apartment with Large Basement

    Apartment with basement; water and heating included; pets allowed.

    12 Bruce Dr, Centereach, NY 11720
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    Centereach Retail Space Available
    Contact for pricing
    2,025 SF

    Centereach Retail Space Available

    Retail space for lease in Centereach Mall.

    15-17 Centereach Mall, Centereach, NY 11720
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    Retail Space Near Smithaven Mall
    Contact for pricing
    4,465 SF

    Retail Space Near Smithaven Mall

    Retail space with high visibility and ample parking available.

    2003-2089 Burr Ln, Centereach, NY
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    Warehouse with Second Floor Office
    $2,600 / Mo

    Warehouse with Second Floor Office

    1700 sq ft warehouse featuring a 500 sq ft office.

    69 Horseblock Rd, Centereach, NY 11720
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    Retail Endcap with High Ceilings
    Contact for pricing
    8,000 SF

    Retail Endcap with High Ceilings

    Retail endcap with conversion potential in Centereach, NY.

    1929 Middle Country Rd, Centereach, NY 11720
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    Centereach Retail Space For Rent
    Contact for pricing
    997 SF

    Centereach Retail Space For Rent

    Retail space available in Centereach Mall with high traffic.

    247-253 Centereach Mall, Centereach, NY 11720
    View details
    Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 16 Active listings in South Setauket, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 8 Properties for Sales.

    Explore Commercial Real Estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail and Restaurant Space Available
    Contact for pricing
    3,231 SF

    Retail and Restaurant Space Available

    Retail and restaurant spaces for rent in Lake Grove.

    Middle Country Rd, Lake Grove, NY 11720
    View details
    Commercial Land for Lease
    Contact for pricing

    Commercial Land for Lease

    Land available for lease with high traffic volume.

    1313 Middle Country Rd, Selden, NY 11784
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    Retail Space in Selden Plaza
    Contact for pricing
    14,673 SF

    Retail Space in Selden Plaza

    Open-air shopping center anchored by Target and Home Depot.

    1137 Middle Country Rd, Selden, NY 11784
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    Lake Grove Office Space Available
    Contact for pricing
    4,500 SF

    Lake Grove Office Space Available

    Ground floor office space for lease on Middle Country Road.

    2780 Middle Country Rd, Lake Grove, NY 11755
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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Land Available For Lease
    $1,600,000
    500 SF

    Land Available For Lease

    Commercial land available for lease with frontage on Holbrook Road.

    10 Holbrook Rd, Centereach, NY 11720
    View details

    Explore Similar Spaces for Sale in South Setauket, NY

    Consider Similar Space for Sale. We found 8 Spaces in Nearby Locations matching your search parameters.

    Centereach Office Space For Sale
    $699,000
    0.30 Acres

    Centereach Office Space For Sale

    Office spaces in high-traffic Centereach location on Middle Country Road.

    2539 Middle Country Rd, Centereach, NY 11720
    View details
    Established Meat and Grocery Store
    $520,000

    Established Meat and Grocery Store

    Turnkey meat and grocery store in high-traffic Centereach location.

    1951 Middle Country Rd, Centereach, NY 11720
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    Centereach Retail Building For Sale
    $1,500,000
    3,500 SF

    Centereach Retail Building For Sale

    Free-standing retail building with stable income and redevelopment potential.

    1442 Middle Country Rd, Centereach, NY 11720
    View details
    Centereach Duplex with Subdivision Potential
    $549,000

    Centereach Duplex with Subdivision Potential

    Two-unit property in Centereach with subdivision potential.

    33 N Washington Ave N, Centereach, NY 11720
    View details
    Centereach Center Retail Investment
    Contact for pricing
    87,949 SF

    Centereach Center Retail Investment

    Fully leased retail center in central Suffolk County.

    1980 Middle Country Rd, Centereach, NY 11720
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    Freestanding Retail Building For Sale
    $1,999,000
    4,200 SF

    Freestanding Retail Building For Sale

    Highly visible, renovated retail building with flexible zoning and ample parking.

    2845 Middle Country Rd, Centereach, NY 11720
    View details
    Centereach Retail Redevelopment Opportunity
    $2,500,000
    5,600 SF

    Centereach Retail Redevelopment Opportunity

    Free-standing retail site with redevelopment potential and ample parking.

    14 Dawn Dr, Centereach, NY 11720
    View details
    Centereach Retail Property For Sale
    $10,440,000
    58,000 SF

    Centereach Retail Property For Sale

    58,000 SF retail property in Centereach, NY.

    2100 Middle Country Rd, Centereach, NY 11720
    View details

    South Setauket, NY Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in South Setauket, NY with 24 listings featured on our commercial real estate exchange. The current inventory includes 210,830,400 square feet of properties with an estimated lease value of $33 SF/Yr.

    Estimated lease rates for Commercial Real Estate in South Setauket, NY begin at $3 SF/Yr, with an average of $11 SF/Yr and extend to $22 SF/Yr.

    In South Setauket, NY, current lease rates show:

    • Individual retail properties positioned at $13
    • Office Properties & Spaces measuring $5
    • Retail properties assessed at $13
    • Retail space calculated at $13
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    Browse Commercial real estate for Lease Near South Setauket, NY

    Popular Searches in South Setauket, NY

    Most Searched ZIP Codes in South Setauket, NY

    • 11720
    • 11741
    • 11772
    • 11738

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