Research Triangle Park, NC Commercial Real Estate for Lease

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Found 138 commercial real estate listings for lease in Research Triangle Park, NC, averaging $33/SF/YR. Use lease type data to compare options faster.
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Freestanding Office Building
Freestanding Office Building

3202 Guess Rd, Durham, NC 27705

Duke Homestead
Contact for pricing

Single-story office property with private offices, reception, kitchen, restroom, and enclosed rear sun porch.

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Durham Industrial Building Near Duke
Durham Industrial Building Near Duke

121 S. LaSalle Street, Durham, NC 27705

Watts Hospital-Hillandale
Contact for pricing
24,000 sqft

24,000 SF industrial building near Duke University and downtown.

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Durham Office Space For Rent
Durham Office Space For Rent

2800 Meridian Parkway, Durham, NC 27713

Contact for pricing
47–79 people  11,869 sqft

Office space available in Durham, close to major transport routes.

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Office Building with Cafe
Office Building with Cafe

2635 E. NC Highway 54, Durham, NC 27713

Contact for pricing
90,000–150,000 sqft  Single tenant

On-site cafe and social gaming area add shared amenities within the building.

4.0/1,000 SF parking  Cafe  Social game area
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Durham Office Space For Rent
Durham Office Space For Rent

2505 Meridian Parkway, Durham, NC 27713

Contact for pricing
44–73 people  11,054 sqft

Office space in prime Durham location with easy access.

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Warehouse Space for Lease
Warehouse Space for Lease

1951 TW Alexander Drive, Durham, NC 27703

Contact for pricing
29,340 sqft

Warehouse space totaling 29,340 SF is available for lease starting 2/1/27.

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Ground-Floor Office Suite
Ground-Floor Office Suite

3708 Lyckan Parkway, Durham, NC 27707

Contact for pricing
5–9 people  1,433 sqft  Ground Floor
5 private offices  1 meeting room  OI

The OI-zoned space has a multi-room configuration and surface parking for employees and visitors.

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Dock-High Warehouse with Office
Dock-High Warehouse with Office

4226 Surles Ct, Durham, NC 27703

Contact for pricing
43,818 sqft  27 ft clear  7 docks  Heavy power
Highway access

Warehouse with 2,453 SF of office space, 7 dock doors, and ESFR sprinkler system near major interchanges.

Sprinklered
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Vibrant Retail Space in Durham
Vibrant Retail Space in Durham

905 West Main Street, Durham, NC 27701

Golden Belt
Contact for pricing
24,174 sqft

Retail space in a lively, historic Durham community.

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GeerHouse Ground-Floor Retail
GeerHouse Ground-Floor Retail

620 Foster Street, Durham, NC 27701

Central Park
Contact for pricing
Multi-tenant  Ground  Built 2023

Ground-floor retail space with an outdoor dining terrace, structured parking, and signage opportunities.

Outdoor dining terrace  Structured parking  Signage and branding opportunities
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Restored Loft-Style Retail Suites
Restored Loft-Style Retail Suites

200 North Mangum Street, Durham, NC 27701

Central Park
Contact for pricing
Multi-tenant
Corner location

Two plug-and-play suites support retail or office use.

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Industrial Land for Outdoor Storage
Industrial Land for Outdoor Storage

1907 Riddle Rd, Durham, NC 27713

Contact for pricing
2.5 acres

A cleared site is being prepared with gravel for a proposed contractor yard, subject to applicable approvals.

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Amenity-Focused Office and Fitness Suite
Amenity-Focused Office and Fitness Suite

2500 Meridian Pkwy, Durham, NC 27713

Coworking
Contact for pricing
Built 1990

Suite offers conference rooms plus fitness and tech hub space with garage doors opening to outdoor seating.

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One City Center Mixed-Use High-Rise
One City Center Mixed-Use High-Rise

110 Corcoran St., Durham, NC 27701

Central Park
Contact for pricing
27-story

Mixed-use space is arranged within a prominent high-rise building.

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Loft-Style Retail Space
Loft-Style Retail Space

501 Washington St., Durham, NC 27701

Warehouse District
Contact for pricing
Built 1924 / renov 2020

A 2020 upfit combines historic character with exposed architectural finishes.

Loft aesthetics  Soaring volume  Exposed roof trusses  Exposed brick walls
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R&D Lab Suites Available
R&D Lab Suites Available

380 East Pettigrew Street, Durham, NC 27701

Downtown
Contact for pricing
812–1,354 people  203,239 sqft

R&D lab suites ranging from 4,345 RSF to 7,381 RSF.

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Masonry Storefront Building
Masonry Storefront Building

125 Orange St, Durham, NC 27701

Central Park
Contact for pricing
Built 1900  masonry

Planned renovation will update a historic commercial space for food, beverage, and neighborhood retail concepts.

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Ground-Floor Retail Space
Ground-Floor Retail Space

311 Liggett Street, Durham, NC 27701

Triple net (NNN) Warehouse District
Contact for pricing
Built 2023

Street-level commercial space integrated into a 2023 multifamily development with a dining terrace, signage opportunities, and customer parking.

Outdoor dining terrace  Signage opportunities
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Office Space with Extensive Amenities
Office Space with Extensive Amenities

42 Moore Drive, Durham, NC 27703

Contact for pricing
1,192–1,988 people  298,206 sqft

Office building featuring on-site cafeteria, fitness center, and health clinic.

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Flex Warehouse with Office Loft
Flex Warehouse with Office Loft

326 Geer St, Durham, NC 27701

Old North Durham
Contact for pricing
barrel vaulted  Built 1949

Flex space combines office areas with a large barrel-vaulted clear span and a usable basement.

Fenced yard  Small office loft  Usable basement  On-site parking
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Durham Office Space For Rent
Durham Office Space For Rent

2700 Meridian Parkway, Durham, NC 27713

Contact for pricing
103–173 people  25,952 sqft

Office space for rent with prime location in Durham.

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Durham Office Space For Rent
Durham Office Space For Rent

2520 Meridian Parkway, Durham, NC 27713

Contact for pricing
461–768 people  115,283 sqft

Office space in Durham, convenient location near I-40 and Highway 55.

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Furnished Loft-Style Creative Space
Furnished Loft-Style Creative Space

316 Holland St., Durham, NC 27701

Central Park
Contact for pricing
Built 1925

Renovated office setting includes utilities, a kitchenette, lounge area, and rooftop outdoor space for gatherings.

Furnished  Rooftop deck  Kitchenette  Lounge area
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Spacious Campus in Durham, NC
Spacious Campus in Durham, NC

2810 Meridian Parkway, Durham, NC 27713

Contact for pricing
90–150 people  22,538 sqft

700,000 SF campus with lake and walking trails.

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