For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Space Uses
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
Price
Price range
$
$
Size
Property size / sq.ft.

Mashpee, MA Commercial Real Estate for Lease

8 results
List
Map
Renovated Office Space on Rte. 28
$3,300 / Mo
1,311 SF

Renovated Office Space on Rte. 28

680 3, Mashpee, MA 02649

Renovated office space with great exposure and ample parking.

  • Great exposure on Rte. 28
  • Totally renovated in 2020
  • Reception area plus 3+ offices
  • Central A/C
  • Plenty of parking
Updated: Dec 31, 2025
View details
Retail/Office Space in Mashpee
$2,000 / Mo
1,100 SF

Retail/Office Space in Mashpee

401/387 Nathan Ellis Hwy, Mashpee, MA 02649

Versatile 1100 sqft retail/office space with ample parking.

  • Highly visible location with ample off‑street parking.
  • 1100 sqft space ready for customization.
  • Private restroom and storage space included.
  • Central air conditioning and natural gas heating.
  • Carpet and laminate flooring.
Updated: Jul 10, 2025
View details
Mashpee Office Suites For Lease
$24 SF/Yr
860 SF

Mashpee Office Suites For Lease

Five modern offices, 150-245 sq ft.

681 Falmouth Rd, Mashpee, MA 02649
View details
Mashpee Retail Center Opportunity
Contact for pricing
141,251 SF

Mashpee Retail Center Opportunity

Prime Cape Cod retail space available.

650 Falmouth Rd, Mashpee, MA 02649
View details
Retail Space in South Cape
Contact for pricing
1,147 SF

Retail Space in South Cape

Retail space available in Mashpee's South Cape Village.

6 Charles St, Mashpee, MA
View details
Retail Space in Mashpee Center
Contact for pricing
753 SF

Retail Space in Mashpee Center

Retail space available in South Cape Village shopping center.

12-18 Charles St, Mashpee, MA
View details
Retail Space in South Cape Village
Contact for pricing
1,005 SF

Retail Space in South Cape Village

Retail space available in Mashpee's South Cape Village.

35 St South, Mashpee, MA
View details
Professional Office Condominium Complex
$1,600 / Mo
850 SF

Professional Office Condominium Complex

Multi-unit office condominium complex with high visibility on Falmouth Road.

766 Falmouth Rd, Mashpee, MA 02649
View details
Based on your search, we've compiled 17 Potential Opportunities for your consideration. Besides 8 Active listings in Mashpee, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

Explore Commercial Real Estate for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Renovated Office Space in Sandwich
$950 / Mo

Renovated Office Space in Sandwich

Open concept office space in Sandwich with high traffic visibility.

135 Sandwich Rd, Sandwich, MA 02563
View details
Falmouth Industrial Bays For Lease
$2,400 / Mo

Falmouth Industrial Bays For Lease

Industrial bays for lease, prefabricated steel construction, built in 2005.

19 Tradesman #3, Falmouth, MA 02536
View details
Falmouth Industrial Bays For Lease
$2,400 / Mo

Falmouth Industrial Bays For Lease

Industrial bays for lease, each with private bath and overhead doors.

19 Or 4, Falmouth, MA 02536
View details
Retail Space in Sandwich Commons
$20 SF/Yr
1,300 SF

Retail Space in Sandwich Commons

Retail unit in high-traffic Sandwich location near Stop & Shop.

77 Quaker Meeting House Rd, Sandwich, MA 02644
View details

Explore Similar Spaces for Sale in Mashpee, MA

Consider Similar Space for Sale. We found 5 Spaces in Nearby Locations matching your search parameters.

New Sherwin-Williams Storefront For Sale
$2,650,000
4,000 SF

New Sherwin-Williams Storefront For Sale

Single-tenant Sherwin-Williams property in Mashpee, Massachusetts, with long-term lease.

413 Nathan Ellis Hwy, Mashpee, MA 02649
View details
Established Bookstore in Prime Location
$300,000

Established Bookstore in Prime Location

Independent bookstore for sale in iconic Cape Cod shopping village.

31 Market St, New Seabury, MA 02649
View details
Flexible Commercial Condo with Storage
$550,000
2,464 SF

Flexible Commercial Condo with Storage

Commercial condo featuring showroom, office space, and fenced yard.

68 Nicolettas Way, Mashpee, MA 02649
View details
Flexible Commercial Condo with Yard
$550,000

Flexible Commercial Condo with Yard

Commercial condo with flexible space, yard, and I-1 zoning.

68 Nicolettas Way, Mashpee, MA 02649
View details
Established Restaurant Business For Sale
$150,000

Established Restaurant Business For Sale

Turnkey restaurant business opportunity with fully equipped kitchen.

681 Falmouth Rd Aka Rte, Mashpee, MA 02649
View details

Mashpee, MA Commercial Real Estate Leasing Opportunities Market Analysis

Explore Commercial Real Estate leasing options in Mashpee, MA with 13 listings featured on our commercial real estate exchange. The current inventory includes 192,143,160 square feet of properties with an estimated lease value of $2,122 /Mo.

Estimated lease rates for Commercial Real Estate in Mashpee, MA begin at $22 SF/Yr, with an average of $424 /Mo and extend to $2,000 /Mo.

In Mashpee, MA, current lease rates show:

  • Office Properties & Spaces positioned at $424
  • Office space measuring $424
  • Individual retail properties assessed at $2,000
  • Retail properties calculated at $2,000
List
Map