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    South Chatham, MA
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    South Chatham, MA Commercial Real Estate for Lease

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    Harwich, MA Orleans, MA Brewster, MA
    Versatile Commercial Space in Chatham
    $3,000/Mo
    1,583 SF
    Versatile Commercial Space in Chatham

    1455 Main Street, Chatham, MA 2633

    1,583 SF commercial space ideal for offices or creative firms.
    • Excellent value at $3,000/mo compared to similar Main Street properties.
    • Versatile layout featuring three office areas, two private rooms, and a 550 SF shared workspace.
    • 1,583 ± SF commercial space ideal for offices, creative firms, or service businesses.
    • Full kitchen and half bath included.
    • Multiple entrances/exits.
    Updated: Apr 22
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    Prime Chatham Retail Space Available
    $40 SF/Yr
    2,592 SF
    Prime Chatham Retail Space Available

    631 Main Street, Chatham, MA 02633

    Exceptional commercial space in a highly desirable Chatham location.
    • Prime commercial location in Chatham, Cape Cod, between the Orpheum Theater and St. Christopher Episcopal Church.
    • High‑exposure location with town parking lot access.
    • Spacious 2,592 sq ft building with an additional 2,000 sq ft high‑ceiling basement for storage.
    • Seller is open to leasing the property.
    • Lease‑purchase option may be available to qualified buyers.
    Updated: Jun 1, 2025
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    Prime Retail Space on Main
    $75 SF/Yr
    3,500 SF
    Prime Retail Space on Main

    3,500 SF retail space in the heart of Chatham.

    450 Main Street, Chatham, MA 2633

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    Main Street Storefront with Apartments
    $75 SF/Yr
    3,500 SF
    Main Street Storefront with Apartments

    3,500 SF storefront with apartments in the heart of Chatham.

    450 Main Street, Chatham, MA 2633

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    Prime Retail Space in Chatham
    Contact for pricing
    1,000 SF
    Prime Retail Space in Chatham

    Corner retail location in the heart of Main Street Chatham.

    470 Main St, Chatham, MA

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    Based on your search, we've compiled 49 Potential Opportunities for your consideration. Besides 5 Active listings in South Chatham, MA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 40 Properties for Sales.

    Commercial real estate for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail Center with Multiple Suites
    Contact for pricing
    1,150 SF
    Retail Center with Multiple Suites

    Leasing available for three retail suites in a RT 6 corridor shopping center.

    1421 Orleans Rd, Harwich, MA 2645

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    Adaptable Commercial Kitchen Space Available
    $3,800/Mo
    Adaptable Commercial Kitchen Space Available

    Commercial kitchen with specialized equipment and adaptable space for rent.

    12 Commerce Drive #1, Orleans, MA 2653

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    Retail Center Near Route 6
    Contact for pricing
    Retail Center Near Route 6

    43,000 SF retail center with strong co-tenancy.

    1421 Orleans-Harwich Road, Harwich, MA 02645

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    Commercial Land For Rent
    Contact for pricing
    Commercial Land For Rent

    Commercial land available for rent in Orleans, Massachusetts.

    24 MA-6A, Orleans, MA 02653

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    Similar Spaces for Sale in South Chatham, MA

    Consider Similar Space for Sale. We found 40 Spaces matching your search parameters.

    Multi-Story Office Building
    $2,399,000
    3,097 SF
    Multi-Story Office Building

    Three finished office levels with central air and prominent Main Street frontage for client-facing and back-office uses.

    697 Main Street, Chatham, MA 02633

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    Two-Story Office Building with Storage
    $1,999,999
    5,712 SF
    Two-Story Office Building with Storage

    Two-story office building with a separate seven-unit storage bay building, renovated in 2013, near Rt. 28.

    31 Meetinghouse Road, South Chatham, MA 02659

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    Well-Maintained Retail Building with Parking
    $1,850,000
    5,101 SF
    Well-Maintained Retail Building with Parking

    Well-maintained retail building with parking and three leased units along Route 28.

    303 Orleans Road, North Chatham, MA 02650

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    Downtown Open-Plan Office Building
    $1,499,000
    2,015 SF
    Downtown Open-Plan Office Building

    Corner-lot office building with open floor plan and 20+ desks, offered with tenants currently in place.

    856 Main Street, Chatham, MA 02633

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    Meservey's Shell: Legacy Opportunity
    $3,500,000
    0.80 Acres
    Meservey's Shell: Legacy Opportunity

    Iconic, family-owned fuel station, convenience store, and car wash.

    1698 Main Street, Chatham, MA 02633

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    Mixed-Use Retail and Residence
    $2,100,000
    1,479 SF
    Mixed-Use Retail and Residence

    Downtown mixed-use building offering a street-facing retail storefront and an independently heated second-floor residence.

    409 Main Street, Chatham, MA 02633

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    Chatham Commercial Building/Warehouse For Sale
    $1,150,000
    3,170 SF
    Chatham Commercial Building/Warehouse For Sale

    Commercial building/warehouse with multiple uses in an industrial area.

    70 Enterprise Dr, Chatham, MA 2633

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    Cape Cod Restaurant & Real Estate
    $950,000
    2,252 SF
    Cape Cod Restaurant & Real Estate

    Successful restaurant with real estate and living accommodations for sale.

    2653 Main Street, South Chatham, MA 02659

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    Chatham In-Town Commercial Property
    $2,799,000
    4,235 SF
    Chatham In-Town Commercial Property

    Renovated commercial space with parking and elevator access.

    697 Main Street, Chatham, MA 2633

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    Chatham Motel with Ocean Views
    $25,000,000
    13,388 SF
    Chatham Motel with Ocean Views

    Rare opportunity: 32-unit motel on 3.2 acres with private beach.

    196 Shore Road, Chatham, MA 02633

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    Chatham Commercial Building/Warehouse For Sale
    $1,150,000
    3,171 SF
    Chatham Commercial Building/Warehouse For Sale

    Commercial building/warehouse with multiple uses in an industrial area.

    70 Enterprise, Chatham, MA 2633

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    Standalone Storefront with Dedicated Parking
    $699,999
    600 SF
    Standalone Storefront with Dedicated Parking

    Well-maintained storefront with eight dedicated parking spaces and established personal services operations in place.

    1772 Main St, Chatham, MA 2633

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    Chatham Commercial or Residential Opportunity
    $700,000
    600 SF
    Chatham Commercial or Residential Opportunity

    Versatile property in Chatham, ideal for business or residential conversion.

    1772 Main St, Chatham, MA 2633

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    Multi-Use Property with Two Buildings
    $1,650,000
    2,586 SF
    Multi-Use Property with Two Buildings

    Two-building commercial property with multi-use space and potential.

    231 Crowell Road, Chatham, MA 2633

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    Downtown Chatham Office Building For Sale
    $1,499,000
    2,015 SF
    Downtown Chatham Office Building For Sale

    2,015 SF office space in downtown Chatham.

    856 Main, Chatham, MA 2633

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    Corner Lot Retail Storefront
    $699,999
    600 SF
    Corner Lot Retail Storefront

    Standalone 600 sq. ft. storefront on a Route 28 corner with eight dedicated parking spaces and existing service tenant.

    1772 Main St, Chatham, MA 2633

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    Chatham Office Building For Sale
    $1,499,000
    2,015 SF
    Chatham Office Building For Sale

    2,015 SF office space in downtown Chatham.

    856 Main Street, Chatham, MA 2633

    View details
    Gas Station with Convenience Store
    $3,500,000
    Gas Station with Convenience Store

    For sale fuel station, convenience store, and car wash on Main Street serving year-round and seasonal customers.

    1698 Main St, Chatham, MA 2633

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    Chatham Commercial Building/Warehouse For Sale
    $1,150,000
    3,170 SF
    Chatham Commercial Building/Warehouse For Sale

    Commercial building/warehouse with multiple uses in Chatham industrial area.

    70 Enterprise Dr, Chatham, MA 2633

    View details

    South Chatham, MA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in South Chatham, MA with 5 listings featured on our commercial real estate exchange. The current inventory includes 11,175 square feet of properties with an estimated lease value of $212 SF/Yr.

    Estimated lease rates for Commercial real estate in South Chatham, MA begin at $22 SF/Yr, with an average of $53 SF/Yr and extend to $75 SF/Yr.
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