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    Barnstable County, MA Commercial Real Estate for Lease

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    Street-Facing Industrial Unit
    Street-Facing Industrial Unit

    40 Evergreen Circle, Unit 1, Mashpee, MA 02649

    $3,500/Mo
    1,725 sqft

    Street-facing industrial space in a 2023 multi-tenant facility with access to Routes 28, 130, and 6.

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    Prime Commercial Unit For Lease
    Prime Commercial Unit For Lease

    410 W Falmouth Highway, West Falmouth, MA 02540

    $28 SF/Yr
    1,350 sqft

    Commercial unit in West Falmouth with high visibility.

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    Office Unit with Private Entrance
    Office Unit with Private Entrance

    155 Katherine Lee Bates Rd Upper, Falmouth, MA 02540

    $2,000/Mo

    Office layout includes open work areas, private offices, conference space, and on-site parking.

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    Restaurant with Outdoor Patio
    Restaurant with Outdoor Patio

    406 Route 6A, East Sandwich, MA 02537

    Contact for pricing
    3,250 sqft 1.50 AC lot

    Restaurant property with indoor dining and an outdoor patio for seasonal service.

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    Move-In Ready Office Unit
    Move-In Ready Office Unit

    180 Teaticket Hwy 4a, Falmouth, MA 02540

    $1,200-$3,750/Mo

    Second-floor commercial suite in a B2-zoned plaza with updated building systems.

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    Office Suite at Port Centre Building
    Office Suite at Port Centre Building

    2a-537 Route 28, Harwich Port, MA

    $1,700/Mo
    1,200 sqft

    Large office suite with private offices, open area, kitchen, and private bath in a mixed-use business building.

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    Harwichport Office Space For Lease
    Harwichport Office Space For Lease

    537 Route 28 #2A, Harwich, MA 02646

    $1,700/Mo
    1,800 sqft

    1,800 SqFt office space in the heart of Harwichport.

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    Unfinished First-Floor Retail Space
    Unfinished First-Floor Retail Space

    255 Stevens Street, Hyannis, MA 02601

    Contact for pricing
    4,500 sqft

    Flexible unfinished commercial space occupies the first floor of a brick building in downtown Hyannis.

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    Single Office Unit
    Single Office Unit

    681 Falmouth Road A20d, Mashpee, MA 02649

    $525/Mo

    Individual office space within a 1984 commercial property near Mashpee Commons and South Cape Plaza.

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    Office Building with Backup Generator
    Office Building with Backup Generator

    265 Orleans Rd, North Chatham, MA

    $4,500/Mo

    Whole-building Generac generator and new windows (summer 2026) support a small business zoned office building.

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    Office Unit for Lease
    Office Unit for Lease

    5 Namskaket Rd 4B, Orleans, MA 02653

    $1,000/Mo

    Lease an office unit with bikeable and somewhat walkable access for convenient day-to-day commuting.

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    Retail Unit For Lease
    Retail Unit For Lease

    927 Main Street, West Dennis, MA 02670

    $2,500/Mo
    1,184 sqft

    Retail space available next to Dunkin Donuts.

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    Industrial Flex Warehouse Unit
    Industrial Flex Warehouse Unit

    5-5 Katie Marie Dr, Bourne, MA 02532

    $1,750/Mo
    1,000 sqft

    Industrial flex unit with a 1299 overhead door, high ceilings, private entrance, and a private bathroom.

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    Yarmouth Port Office Space
    Yarmouth Port Office Space

    13 Willow St, Yarmouth, MA 02675

    $3,500/Mo
    2,389 sqft

    Turn-key office space available for lease in Yarmouth Port.

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    Single Office Unit
    Single Office Unit

    681 Falmouth Road A25, Mashpee, MA 02649

    $495/Mo

    Unit A25 provides a dedicated office at Deer Crossing along Falmouth Road.

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    Industrial Flex Warehouse Unit
    Industrial Flex Warehouse Unit

    5 Katie Marie Drive, #5, Bourne, MA 02532

    $1,750/Mo
    1,000 sqft

    Unit 5 offers a flex warehouse layout with a 12’x12’ overhead door, high ceilings, private entrance, and bathroom.

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    Single-Office Unit
    Single-Office Unit

    A20d-681 Falmouth Rd, Mashpee, MA 02649

    $525/Mo

    One office unit is available near established commercial destinations in Mashpee.

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    Two-Story Steel-and-Brick Office Building
    Two-Story Steel-and-Brick Office Building

    29 Bassett Lane, Hyannis, MA 02601

    $24 SF/Yr

    Adaptable professional space includes multi-zone climate control and a partially finished lower level.

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    Professional Office Units
    Professional Office Units

    32 Commercial St, South Yarmouth, MA 02664

    Contact for pricing
    6,000 sqft

    Office accommodation is available within a commercial property on Commercial Street.

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    Main Street Office Condominium
    Main Street Office Condominium

    32 Main Street UNIT B, Orleans, MA 02653

    Contact for pricing
    3,595 sqft

    Office condominium with multiple private rooms, shared work areas, reception, conference space, kitchen, bathrooms, and basement storage.

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    Office Unit with Route Frontage
    Office Unit with Route Frontage

    80 Davis Straits # 104A, Falmouth, MA 02540

    $24 SF/Yr

    Flexible commercial suite with private workspace, meeting area, kitchenette, bathroom, and on-site parking.

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    Office Unit in Commercial Building
    Office Unit in Commercial Building

    5 Namskaket Road, Unit 4B, Orleans, MA 02653

    $1,000/Mo
    350 sqft

    Office unit for lease in Orleans, MA 02653 within a commercial property.

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    Main-Road Office Building
    Main-Road Office Building

    265 Orleans Road, North Chatham, MA 02650

    $4,500/Mo

    GB 3 zoning, road frontage, and substantial parking access complement professional office operations.

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    Upper-Level Office Units
    Upper-Level Office Units

    A20h-681 Falmouth Rd, Mashpee, MA 02649

    $450-$525/Mo

    Individual office suites are available within Deer Crossing in Plaza.

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