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    Acton, MA Commercial Real Estate for Lease

    18 results
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    Retail/Medical Space Near Route 2
    $21 SF/Yr
    3,000 SF

    Retail/Medical Space Near Route 2

    222 Main St, Acton, MA 01720

    Freestanding building with retail/medical space, superb visibility, easy access.

    • Superb visibility and easy accessibility for customers.
    • Prime location: Less than 1/4 mile from Route 2 (exit 42) and the Acton Commuter Rail (MBTA) station.
    • Suitable for medical or retail use with approximately 3,000 sq ft of space.
    • Recent building improvements in 2018: new roof, HVAC, exterior painting, and sidewalk.
    • Located in a plaza with established businesses: Dunkin Donuts, hardware store, and restaurant.
    Updated: Jul 31, 2025
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    Professional Office Space on Route 2A
    $22 SF/Yr

    Professional Office Space on Route 2A

    77 Great Rd, Acton, MA 01720

    Well-maintained office space with ample parking and great visibility.

    • Centrally‑located professional building on Route 2A with great visibility in a busy shopping and office plaza.
    • Rare vacancy in a highly desired building.
    • Approximately 2,630 sqft suite on the second floor with a side entrance that acts as a first floor (no stairs).
    • Includes a large reception area, en suite bath, and 12 separate offices, most with windows and great sunlight.
    • Utilities included.
    Updated: Apr 17, 2025
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    Acton Retail Center - Main St
    Contact for pricing
    6,755 SF

    Acton Retail Center - Main St

    Prime Acton retail space available. Multiple units, flexible sizes.

    252 Main St, Acton, MA 01720
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    Acton Retail Center: Prime Location
    Contact for pricing
    75,529 SF

    Acton Retail Center: Prime Location

    Upscale Shops, High Traffic, Great Road

    145 Great Rd, Acton, MA 01720
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    Retail Space in Acton, MA
    $19 SF/Yr
    3,000 SF

    Retail Space in Acton, MA

    3,000 SF retail space available for lease.

    77 Powdermill Rd, Acton, MA 01720
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    Retail Space in Acton Center
    Contact for pricing
    23,000 SF

    Retail Space in Acton Center

    Neighborhood retail shopping center anchored by Donelan’s Supermarket.

    246-266 Great Rd, Acton, MA 01720
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    Retail Space in Acton Plaza
    Contact for pricing
    8,400 SF

    Retail Space in Acton Plaza

    Grocery-anchored neighborhood center in affluent Acton trade area.

    295-307 Main St, Acton, MA 01720
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    Industrial Space Available For Lease
    Contact for pricing
    19,200 SF

    Industrial Space Available For Lease

    19,200 SF industrial space for lease in Acton, MA.

    115 River St, Acton, MA 01720
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    Retail Space Near Stop & Shop
    Contact for pricing

    Retail Space Near Stop & Shop

    Retail space available near Stop & Shop and affluent communities.

    Acton, MA 01720
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    Acton Office/R&D Space For Rent
    Contact for pricing
    20,000 SF

    Acton Office/R&D Space For Rent

    Two-story, 20,000 SF office/R&D building with loading dock.

    100 Discovery Way, Acton, MA 01720
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    Prime Retail Space on Great Road
    Contact for pricing
    4,000 SF

    Prime Retail Space on Great Road

    Highly visible retail space in a heavily trafficked corridor.

    425 Great Rd, Acton, MA 01720
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    Retail/Office Space in Acton
    $19 SF/Yr
    16,800 SF

    Retail/Office Space in Acton

    3,000 SF retail/office space available in Acton, MA.

    77 Powder Ml Rd, Acton, MA 01720
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    Retail Space in Acton Plaza
    Contact for pricing
    2,990 SF

    Retail Space in Acton Plaza

    Grocery-anchored neighborhood center in affluent Acton, MA.

    201-393 Massachusetts Ave, Acton, MA 01719
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    Acton Flex Space Available
    Contact for pricing
    50,000 SF

    Acton Flex Space Available

    50,000 SF flex space with loading docks and parking.

    8 Post Office Sq, Acton, MA 01720
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    Retail Space Available For Lease
    $15 SF/Yr
    2,493 SF

    Retail Space Available For Lease

    Retail property with 2493 square feet available for lease.

    436 Great Rd, Acton, MA 01720
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    Retail Space in Acton Center
    Contact for pricing
    1,220 SF

    Retail Space in Acton Center

    Retail space available in a busy Acton shopping center.

    100 Powdermill Rd, Acton, MA 01720
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    Acton Office Spaces Available
    Contact for pricing
    1,000 SF

    Acton Office Spaces Available

    Office spaces for rent in Acton, Massachusetts.

    42-54 Nonset Path, Acton, MA 01720
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    Retail Space Near Route 111
    Contact for pricing
    2,478 SF

    Retail Space Near Route 111

    2,478 SF endcap retail space with high visibility.

    411 Massachusetts Ave, Acton, MA 01720
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    Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 18 Active listings in Acton, MA, we suggest exploring alternatives. Similar 11 Properties for Sales.

    Explore Similar Spaces for Sale in Acton, MA

    Consider Similar Space for Sale. We found 11 Spaces in Nearby Locations matching your search parameters.

    West Acton Village Retail Condo
    $259,900
    1,496 SF

    West Acton Village Retail Condo

    Prime commercial condo in vibrant West Acton, ideal for retail.

    25 Spruce St, Acton, MA 01720
    View details
    Six-Unit Multifamily Investment Opportunity
    $2,200,000

    Six-Unit Multifamily Investment Opportunity

    Six units in three duplexes near West Acton and train.

    4 Crestwood Ln, Acton, MA 01720
    View details
    48-Unit Multifamily Investment Opportunity
    $11,000,000

    48-Unit Multifamily Investment Opportunity

    Value-add multifamily property in desirable Acton, Massachusetts.

    1-9 Bayberry Rd, Acton, MA 01720
    View details
    Acton Flex/RD Space For Sale
    $2,995,000
    16,185 SF

    Acton Flex/RD Space For Sale

    16,186 SF Flex/RD space in Acton industrial park.

    15 Craig Rd, Acton, MA 01720
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    Established Retail Building on 2A
    $1,100,000
    4,186 SF

    Established Retail Building on 2A

    Boutique retail building with high visibility and conversion potential.

    6 Great Rd, Acton, MA 01720
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    Historic Landmark with Prime Frontage
    $1,500,000

    Historic Landmark with Prime Frontage

    Historic landmark with excellent visibility in a vibrant commercial area.

    144 Great Rd, Acton, MA 01720
    View details

    Acton, MA Commercial Real Estate Leasing Opportunities Market Analysis

    Explore Commercial Real Estate leasing options in Acton, MA with 29 listings featured on our commercial real estate exchange. The current inventory includes 1,101,763,080 square feet of properties with an estimated lease value of $75 SF/Yr.

    Estimated lease rates for Commercial Real Estate in Acton, MA begin at $15 SF/Yr, with an average of $18 SF/Yr and extend to $21 SF/Yr.

    In Acton, MA, current lease rates show:

    • Individual retail properties positioned at $18
    • Retail properties measuring $18
    • Retail space assessed at $18
    • Healthcare properties calculated at $21
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    Browse Commercial real estate for Lease Near Acton, MA

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    Most Searched ZIP Codes in Acton, MA

    • 01720
    • 01719

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