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    La Jolla, CA Commercial Real Estate for Lease

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    Found 1,026 commercial real estate listings for lease in La Jolla, CA, averaging $22/SF/YR. Use lease type data to compare options faster.
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    Sorrento Mesa Office Space
    Sorrento Mesa Office Space

    5405 Morehouse Dr, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    24–40 people  6,126 sqft

    Office space available for rent in Sorrento Mesa.

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    San Diego Flex/Industrial Space
    San Diego Flex/Industrial Space

    3954 Murphy Canyon Rd., San Diego, CA 92123

    Kearny Mesa
    Contact for pricing
    4,402 sqft  Built 2026

    Flex/industrial space available for lease in San Diego, CA.

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    Sorrento Valley Road Office Space
    Sorrento Valley Road Office Space

    10665 Sorrento Valley Road, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    152–254 people  38,208 sqft

    Office space available for rent in Sorrento Valley, San Diego.

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    La Jolla First Floor Office
    La Jolla First Floor Office

    San Diego, CA

    Full service Little Italy
    Contact for pricing
    7–11 people  7 spaces  1,782 sqft  3.45 acres

    First floor office space available for rent in La Jolla.

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    Warehouse Flex Suite with Offices
    Warehouse Flex Suite with Offices

    7898 Ostrow St, San Diego, CA 92111

    Modified gross Clairemont Mesa East
    Contact for pricing
    1,440 sqft  2 drive-in  Multi-tenant
    EMX-1

    Multi-tenant flex/warehouse suite featuring two GL doors, two offices, and one restroom.

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    Office Suite with Private Offices
    Office Suite with Private Offices

    101 W Broadway, San Diego, CA 92101

    Horton Plaza
    Contact for pricing
    9–15 people  2,290 sqft
    3 private offices

    Second-generation office space featuring three private offices along the window line and an open workstation area.

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    Office Space Available For Rent
    Office Space Available For Rent

    4939 Directors Place, San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    248–413 people  62,082 sqft

    62,082 square foot office space available for rent.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    1621 Grand Ave, San Diego, CA 92109

    Mission Bay
    Contact for pricing

    Second-floor office space offered as one suite or combined into a larger 3,000 SF option, with off-street parking.

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    Medical Space For Rent
    Medical Space For Rent

    3444 Kearny Villa Road, San Diego, CA 92123

    Birdland
    Contact for pricing
    8,287 sqft

    Medical space available for lease in San Diego, CA.

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    Office Space Near San Diego Airport
    Office Space Near San Diego Airport

    4990 North Harbor Drive, San Diego, CA 92106

    Roseville / Fleet Ridge
    Contact for pricing
    7–11 people  1,754 sqft

    Office space for rent with immediate airport and I-5 access.

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    San Diego Office Space Available
    San Diego Office Space Available

    4250 Pacific Highway, San Diego, CA 92110

    Midway District
    Contact for pricing
    257–428 people  64,277 sqft

    Office space available for lease in San Diego, CA.

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    Class A Office Building
    Class A Office Building

    701 B St, San Diego, CA 92101

    Core-Columbia
    Contact for pricing
    94–157 people  23,620 sqft

    24-story Class A office building with bay views.

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    Industrial Space with Existing Racking
    Industrial Space with Existing Racking

    9255 Customhouse Plaza, San Diego, CA 92154

    Otay Mesa
    Contact for pricing
    50,069 sqft  Built 1990

    Industrial space featuring ESFR sprinklers, high ceilings, and concrete truck court.

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    Downtown San Diego Office Space
    Downtown San Diego Office Space

    610 W Ash St, San Diego, CA 92101

    Little Italy
    Contact for pricing
    244–407 people  61,062 sqft

    61062 SF office space available for lease.

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    Office Suite with Large Patio
    Office Suite with Large Patio

    16707 Via Del Campo Ct, San Diego, CA 92127

    Triple net (NNN) Rancho Bernardo
    Contact for pricing
    108–180 people  1 space  27,046 sqft

    3rd-floor office suite offers a large patio with valley views and 10-foot ceilings.

    Patio
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    Miramar Road Flex Space Available
    Miramar Road Flex Space Available

    8008 Miramar Road, San Diego, CA 92126

    Miramar
    Contact for pricing
    2,169 sqft  Built 1982

    Flex space with private offices, roll-up door, and parking.

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    San Diego Specialty Property
    San Diego Specialty Property

    4767 Nexus Centre Dr., San Diego, CA 92121

    Sorrento Valley
    Contact for pricing
    75,800 sqft  Built 2026

    75,800 sqft specialty property available for rent.

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    Retail Building Former Rite Aid
    Retail Building Former Rite Aid

    1745 Euclid Avenue, San Diego, CA

    Emerald Hills
    Contact for pricing
    17,500 sqft

    Retail building available for rent, formerly a Rite Aid.

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    Street-Front Storefront Retail Suite
    Street-Front Storefront Retail Suite

    1013 Morena Blvd, San Diego, CA 92110

    Morena
    Contact for pricing
    3,996 sqft

    Storefront retail suite with prominent Morena Blvd frontage and available enclosed space for retail use.

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    Endcap Retail Space
    Endcap Retail Space

    3609 Midway Dr, San Diego, CA 92110

    Midway District
    Contact for pricing
    1,400 sqft

    Endcap retail space available for lease, offering a dedicated storefront configuration.

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    Retail Shopping Center
    Retail Shopping Center

    1640 Camino Del Rio N, San Diego, CA 92108

    Mission Valley East
    Contact for pricing
    1,545 sqft

    Retail space in Mission Valley anchored by major retailers including Target and AMC, with strong daytime population and traffic.

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    Fully Furnished Electronics Lab Office
    Fully Furnished Electronics Lab Office

    12121 Scripps Summit Dr, San Diego, CA 92131

    Miramar Ranch North
    Contact for pricing
    57–95 people  1 space  14,362 sqft

    Office space is fully furnished and set up for small electronics lab use with plug-and-play functionality.

    Furnished  Small electronics lab
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    Former Bank Branch on Signalized Corner
    Former Bank Branch on Signalized Corner

    1415-1445 India St, San Diego, CA 92101

    Triple net (NNN) Little Italy
    Contact for pricing
    4,607 sqft

    Former bank branch on a signalized hard corner with two available parking spaces.

    2 parking spaces
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    La Jolla Medical Office Space
    La Jolla Medical Office Space

    5726 La Jolla Blvd, La Jolla, CA

    Triple net (NNN)
    Contact for pricing
    1,500 sqft  0.52 acres

    Turn-key medical office in La Jolla's Bird Rock community.

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    Most Searched ZIP Codes in La Jolla, CA

    • 92121
    • 92101
    • 92123
    • 92154
    • 92130
    • 92108
    • 92127
    • 92126
    • 92037
    • 92128
    • 92110
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