La Jolla, CA Commercial Real Estate for Lease

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Found 1,026 commercial real estate listings for lease in La Jolla, CA, averaging $22/SF/YR. Use lease type data to compare options faster.
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Built-Out Restaurant Space
Built-Out Restaurant Space

427 9th Ave, San Diego, CA 92101

East Village
Contact for pricing
1,810 sqft
Far Corner Pizza, Cafe de l’Opera co-tenants

Second-generation commercial space includes a patio and fronts J Street in San Diego’s Ballpark District.

Patio
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Mixed-Use Property with Hotel Suites
Mixed-Use Property with Hotel Suites

2611 Adams Avenue, San Diego, CA 92116

Mission Valley East
Contact for pricing
Built 2025 / renov 2025

Furnished lodging suites operate alongside a separately leased restaurant component.

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Kearny Mesa Medical Office Space
Kearny Mesa Medical Office Space

3750 Convoy St, San Diego, CA

Clairemont Mesa East
Contact for pricing
2,452 sqft  5.85 acres

Medical office space in a convenient Kearny Mesa location.

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Retail Space in Mira Mesa
Retail Space in Mira Mesa

9388 Mira Mesa Boulevard, San Diego, CA 92126

Mira Mesa
Contact for pricing
24,473 sqft

Retail opportunity at a signalized corner in San Diego.

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San Diego Industrial Space Available
San Diego Industrial Space Available

1425 Corporate Center Dr, San Diego, CA 92154

Ocean Crest
Contact for pricing
14,802 sqft  Built 2004

Industrial property with 14,802 square feet available for rent.

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Office Building with Conference Center
Office Building with Conference Center

1450 Frazee Rd, San Diego, CA 92123

Linda Vista
Contact for pricing
39–65 people  9,798 sqft  Multi-tenant

Move-in-ready office suites are available in a building featuring a modern lobby, conference center, and covered outdoor seating.

Modernized lobby  Conference center  Remodeled common areas  Covered outdoor seating area
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Single Tenant Office Space
Single Tenant Office Space

170 Laurel St, San Diego, CA 92101

Gross Park West
Contact for pricing
21–36 people  1 space  5,426 sqft

Office space available for single tenant occupancy.

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Creative Office Space Available
Creative Office Space Available

2355 Northside Dr, San Diego, CA 92108

Mission Valley East
Contact for pricing
13–22 people  3,334 sqft

Creative office space featuring open kitchen and upgraded finishes.

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Free-Standing Office Building
Free-Standing Office Building

9565 Waples St, San Diego, CA 92121

Full service Sorrento Valley
Contact for pricing
26–44 people  2 spaces  6,716 sqft
Highway access

Free-standing office building with elevator service, expansive windows, and on-site plus adjacent street parking.

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Class A Office Space Available
Class A Office Space Available

8899 University Center Ln, San Diego, CA 92122

University City
Contact for pricing
8–13 people  2,038 sqft

Built-out suites in Class A building with excellent accessibility.

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Office Space with Renovated Atrium
Office Space with Renovated Atrium

5405 Morehouse Dr, San Diego, CA 92121

Sorrento Valley
Contact for pricing
24–40 people  6,126 sqft

Renovated atrium with a water feature, outdoor seating, and WiFi near a retail center with major national tenants.

4.0/1,000 SF parking  Covered parking structure  Renovated atrium with water feature  Outdoor seating
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Carmel Valley Medical Office Space
Carmel Valley Medical Office Space

4765 Carmel Mountain Rd, San Diego, CA

Sorrento Valley
Contact for pricing
1,329 sqft  2.59 acres

Class-A medical office space in Carmel Valley for rent.

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Available Office and Medical Space
Available Office and Medical Space

10355 Science Center Drive, San Diego, CA 92121

Torrey Pines
Contact for pricing
59–98 people  14,773 sqft

Office and medical space available for rent in San Diego.

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Scripps Ranch Business Center Space
Scripps Ranch Business Center Space

10121 - 10123 Carroll Canyon Road, San Diego, CA 92131

Scripps Ranch
Contact for pricing
18,732 sqft

Located in the attractive Scripps Ranch Business Center environment.

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Renovated Office Atrium Space
Renovated Office Atrium Space

5405 Morehouse Dr, San Diego, CA 92121

Sorrento Valley
Contact for pricing
13–23 people  3,477 sqft

Recently renovated atrium with water feature, outdoor seating, and WiFi within a covered parking setting.

4.0/1,000 SF parking  Water feature  Outdoor seating  WiFi
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Loft-Style Office Space
Loft-Style Office Space

2045 Kettner Blvd, San Diego, CA 92101

Triple net (NNN) Little Italy
Contact for pricing
23–39 people  1 space  5,867 sqft  2-story

Two-story loft-style office space for lease.

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Retail Space Available For Rent
Retail Space Available For Rent

6906 Miramar Rd, San Diego, CA 92121

Sorrento Valley
Contact for pricing
10,100 sqft  Built 2000

Retail property with 10100 square feet available for lease.

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Flex Space in Renovated Campus
Flex Space in Renovated Campus

5510 Morehouse Dr, San Diego, CA 92121

Sorrento Valley
Contact for pricing
12,196 sqft  Renovated 2021

Flex space available within a campus renovated in 2021, offering approximately 3 parking spaces per 1,000 SF.

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Class A Office Project
Class A Office Project

12707 & 12777 High Bluff Dr, San Diego, CA 92130

Carmel Valley
Contact for pricing
26–44 people  6,700 sqft

Class A office space for rent in Del Mar Heights.

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Turnkey Office Spec Suite
Turnkey Office Spec Suite

101 W Broadway, San Diego, CA 92101

Horton Plaza
Contact for pricing
24–41 people  6,203 sqft

Newly built office suite with double-door entry, reception, 13 private offices, and conference room.

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Mission Valley Sublease Opportunity
Mission Valley Sublease Opportunity

3111 Camino Del Rio N, San Diego, CA 92108

Mission Valley East
Contact for pricing
66–111 people  16,656 sqft

High-end creative office space available for sublease in Mission Valley.

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Coastal Office Units
Coastal Office Units

1454 Garnet Avenue, San Diego, CA 92109

Pacific Beach
Contact for pricing
Highway access

The Pacific Beach setting connects office users with local transit, Interstate 5, and central San Diego communities.

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Amenitized Office Campus in San Diego
Amenitized Office Campus in San Diego

16855 West Bernardo Drive, San Diego, CA 92127

Rancho Bernardo
Contact for pricing
79–132 people  19,928 sqft

Rancho Bernardo office campus with amenities and flexible suites.

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Office Space Available For Rent
Office Space Available For Rent

10021 Willow Creek Rd, San Diego, CA 92131

Scripps Ranch
Contact for pricing
30–50 people  7,615 sqft

7,615 square foot office space available for rent.

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