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Woodruff, SC Specialty Properties for Sale

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Partially Renovated Building on Highway
$275,000
1.10 Acres

Partially Renovated Building on Highway

12117 Highway 221, Woodruff, SC 29388

2,792 SF building with development potential in thriving Woodruff area.

  • Prime location in the thriving Woodruff growth area with high traffic frontage on Highway 221
  • Significant investment potential with ample room for expansion and customization
  • Partially renovated 2,792 SF building with new HVAC, updated electrical, and new windows
  • Multiple points of ingress/egress, suitable for various uses (childcare, school, office, retail)
  • Ample parking available
Updated: Sep 24, 2025
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Based on your search, we've compiled 28 Potential Opportunities for your consideration. Besides 1 Active listings in Woodruff, SC, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 23 Off-Market properties to explore as potential leads

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Spartanburg NNN Leased Investment Property
$2,009,839
18,036 SF

Spartanburg NNN Leased Investment Property

NNN leased investment property with corporate tenant in Spartanburg, SC.

121 Southport Rd, Spartanburg, SC 29306
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Caliber Collision NNN Investment Opportunity
Contact for pricing

Caliber Collision NNN Investment Opportunity

Recently renewed 15-year NNN corporate lease with zero landlord responsibilities.

119 Southport Rd, Spartanburg, SC 29306
View details
Mauldin Car Wash - Investment Opportunity
$526,675
26,136 SF

Mauldin Car Wash - Investment Opportunity

Prime Mauldin location, high traffic count.

207 Butler Rd, Mauldin, SC 29662
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Drive-Thru Investment Opportunity
$2,815,500
950 SF

Drive-Thru Investment Opportunity

Net lease investment opportunity with a national brand tenant.

203 South Main St, Mauldin, SC 29662
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Explore Off-Market Properties in Woodruff, SC

Consider similar Off-Market properties in Woodruff, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

270 South St

270 South St

Churches & religious facilities • 2,625 SF
Value Estimation by Request
270 South St, Woodruff, SC 29388
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900 Buncombe St Ext

900 Buncombe St Ext

DAY CARE, PRE-SCHOOL • 2,400 SF
Value Estimation
$280,000
900 Buncombe St Ext, Woodruff, SC 29388-9007
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505 Workman Ave

505 Workman Ave

FUNERAL HOME • 2,740 SF
Value Estimation by Request
505 Workman Ave, Woodruff, SC 29388
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915 Cross Anchor Rd

915 Cross Anchor Rd

DAY CARE, PRE-SCHOOL • 46.65 Acres
Value Estimation by Request
915 Cross Anchor Rd, Woodruff, SC 29388-9525
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385 Sloan Rd

385 Sloan Rd

FUNERAL HOME • 1,800 SF
Value Estimation
$190,000
385 Sloan Rd, Woodruff, SC 29388-9041
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205 Sj Workman Hwy

205 Sj Workman Hwy

DAY CARE, PRE-SCHOOL • 39.80 Acres
Value Estimation by Request
205 Sj Workman Hwy, Woodruff, SC 29388-8780
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410 Hayne St

410 Hayne St

DAY CARE, PRE-SCHOOL • 2,772 SF
Value Estimation
$200,000
410 Hayne St, Woodruff, SC 29388-1926
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710 Cross Anchor Rd

710 Cross Anchor Rd

DAY CARE, PRE-SCHOOL • 3,081 SF
Value Estimation by Request
710 Cross Anchor Rd, Woodruff, SC 29388-2301
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734 Bellview Rd

734 Bellview Rd

SBE - SPECIAL ASSESSMENTS • 0.28 Acres
Value Estimation by Request
734 Bellview Rd, Woodruff, SC 29388-9721
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14 Sloan Lk Rd

14 Sloan Lk Rd

SBE - SPECIAL ASSESSMENTS • 0.63 Acres
Value Estimation by Request
14 Sloan Lk Rd, Woodruff, SC 29388-9043
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8272 Hwy 221

8272 Hwy 221

VETERINARY, ANIMAL HOSPITAL • 9,744 SF
Value Estimation by Request
8272 Hwy 221, Woodruff, SC 29388-8879
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137 Mcarthur St

137 Mcarthur St

DAY CARE, PRE-SCHOOL • 2,400 SF
Value Estimation
$75,000
137 Mcarthur St, Woodruff, SC 29388
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165 Gray St

165 Gray St

FUNERAL HOME • 3,328 SF
Value Estimation by Request
165 Gray St, Woodruff, SC 29388-1715
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1225 Cross Anchor Rd

1225 Cross Anchor Rd

FUNERAL HOME • 8,296 SF
Value Estimation
$565,000
1225 Cross Anchor Rd, Woodruff, SC 29388-9592
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Hwy 101

Hwy 101

FUNERAL HOME • 980 SF
Value Estimation by Request
Hwy 101, Woodruff, SC 29388
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Wofford St

Wofford St

FUNERAL HOME • 1.68 Acres
Value Estimation by Request
Wofford St, Woodruff, SC 29388
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Bill Pearson Rd

Bill Pearson Rd

FUNERAL HOME • 1.15 Acres
Value Estimation by Request
Bill Pearson Rd, Woodruff, SC 29388
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Chicken Foot Crk Rd

Chicken Foot Crk Rd

FUNERAL HOME • 4,441 SF
Value Estimation by Request
Chicken Foot Crk Rd, Woodruff, SC 29388
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1620 Kilgore Brg Rd

1620 Kilgore Brg Rd

FUNERAL HOME • 0.25 Acres
Value Estimation by Request
1620 Kilgore Brg Rd, Woodruff, SC 29388-9559
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Cross Anchor Rd

Cross Anchor Rd

FUNERAL HOME • 3,841 SF
Value Estimation by Request
Cross Anchor Rd, Woodruff, SC 29388
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Kelly Rd

Kelly Rd

FUNERAL HOME • 1,956 SF
Value Estimation by Request
Kelly Rd, Woodruff, SC 29388
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Switzer Greenpond Rd

Switzer Greenpond Rd

FUNERAL HOME • 1,366 SF
Value Estimation by Request
Switzer Greenpond Rd, Woodruff, SC 29388
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900 Buncombe St Ext

900 Buncombe St Ext

DAY CARE, PRE-SCHOOL • 0.18 Acres
Value Estimation by Request
900 Buncombe St Ext, Woodruff, SC 29388-9007
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Woodruff, SC Specialty Properties Investment Opportunities Market Analysis

Explore 24 specialty properties for sale in Woodruff, SC on our real estate platform. These investment opportunities span a total of 6,565,086 square feet of properties for sale, with an estimated market value of $9,560,000.

Prices for properties in Woodruff, SC start at $70,000, averaging $503,157, and reaching up to $2,775,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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