Mississippi Spa & wellness properties for sale

Updated: Jul 19

Three-Zone Medical Center

160 Fountains Boulevard, Madison, MS 39110

$9,750,000

73,898 sqft 1.71 AC lot

Three independently accessible zones: ambulatory surgery, medical office, and MediSpa
ASC includes 2 operating rooms, 3 PACU recovery bays, 2 pre‑operative bays, and 1 procedure room
Medical office buildout includes 6 exam rooms, 7 private offices, and administrative space
MediSpa suite offers 4 treatment rooms and a dedicated entry
Mississippi Ambulatory Surgical Facility license, CMS Medicare ASC certification, and QUAD A accreditation

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Updated: Feb 5

Nail Spa Commercial Building

703 Hwy 45 N, Columbus, MS 39701

$700,000

1,984 sqft

1,984‑square‑foot brick commercial building configured for nail spa operations
10 adult manicure chairs, one child manicure chair, and 10 manicure stations
11 pedicure stools, two restrooms, two storage areas, and a dedicated laundry room
Additional interior room suited to waxing or other services
Roof and HVAC approximately 4 years old; updated ductwork and electrical improvements

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Medical Office Building

332 N 25th Ave, Hattiesburg, MS 39401

$145,000

The existing setup supports chiropractic care and massage therapy within a versatile professional setting.

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Dual-Suite Office Property

169 Lameuse St, Biloxi, MS 39530

$663,000

4,000 sqft

Two separately configured units provide offices, reception areas, break rooms, and restrooms.

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Spa and Wellness Property

750 1/2 Tuscaloosa Rd, Columbus, MS 39702

$99,900

1,500 sqft 0.50 AC lot

Commercially zoned property with public water service and an established beauty-shop use.

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Spa & Wellness Property

4912 Kreole Avenue, Moss Point, MS 39563

$69,900

1,025 sqft 0.27 AC lot

The building is currently used as a beauty salon on Kreole Avenue.

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Historic Spa & Wellness Property

247 Delta Ave, Clarksdale, MS 38614

$149,000

2,151 sqft

Medical aesthetics practice occupies a downtown storefront with private rooms, reception space, and flexible commercial areas.

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Spa and Wellness Commercial Building

151 E Franklin St, Natchez, MS 39120

$225,000

2,436 sqft

Commercial property with prior beauty and spa use and flexibility for office or retail occupancy.

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Class A Ambulatory Surgical Center

160 Fountains Boulevard, Madison, MS 39110

$9,750,000

15,967 sqft

2017-built ambulatory surgical center with independent medical office and MediSpa components connected by a climate-controlled conservatory.

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Turnkey Hair Salon Opportunity

415 Old Pass Rd, Long Beach, MS 39560

$239,000

1,296 sqft 0.17 AC lot

Fully operational hair salon for sale with all equipment.

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Corner Retail Space with Flexible Layout

907 S Locust Street, Mccomb, MS 39648

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1,560 sqft

Flexible commercial space includes kitchen appliances, bathing facilities, and dedicated parking.

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Office Unit with Private Entrance

424 Highway 90, Gautier, MS 39553

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826 sqft

Renovated upstairs office suite with an adaptable layout, private restroom, built-in storage, and included utilities.

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Beauty Salon with Nail Area

12001 Mobile Ave, Gulfport, MS 39503

$129,000

960 sqft

Established salon layout includes plumbing-equipped stations, a dedicated nail section, and a private rear room for office or service use.

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6-Office Suite in Frenchman Square

2436 Pass Road, Biloxi, MS 39531

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Lower-level commercial space with private rooms, a kitchen, bathroom, and front lobby.

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Spa & Wellness Property with Salon Equipment

2608 13th, Gulfport, MS 39501

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Salon equipment is included, and the tenant pays all utility costs.

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Salon Property with On-Site Parking

301 Decatur Street, Newton, MS 39345

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0.20 AC lot

Corner-lot location offers street frontage, a handicap ramp, and access to on-site parking.

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Nail Salon Property with Storage

203 Decatur Street, Newton, MS 39345

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0.40 AC lot

Established operation includes furnishings, supplies, equipment, inventory, customer parking, and an upstairs storage area.

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Mississippi Spa & Wellness Properties Market Trends and Statistics

Explore 17 spa & wellness properties for sale in Mississippi, showcased through 17 active listings on our real estate platform. These investment opportunities span a total of 107,603 square feet of properties for sale, with an estimated market value of $21,919,800.

Sale prices for spa & wellness properties in Mississippi start at $69,900, averaging $1,992,709, and reaching up to $9,750,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.