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Mayo, FL Retail Space for Sale

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Commercial Property in Growing Region
$860,000
1.46 Acres

Commercial Property in Growing Region

130 NE Clyde Avenue, Mayo, FL 32066

1.46-acre property suitable for various commercial ventures in Mayo, FL.

  • Strategic location halfway between Gainesville and Tallahassee in Mayo, the county seat of Lafayette County.
  • Large 1.46‑acre lot with a 2,623 square foot building suitable for various commercial ventures.
  • Located in the 'Gateway to Growth' region of North Central Florida with a supportive environment for economic development.
  • Built in 2019, featuring brick construction, central heating and air, and a blacktop driveway.
  • Zoning and location suitable for a wide range of service‑oriented businesses, including retail, office, catering, or skilled trades.
Updated: Sep 8, 2025
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Based on your search, we've compiled 26 Potential Opportunities for your consideration. Besides 1 Active listings in Mayo, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 19 Off-Market properties to explore as potential leads, plus 2 Land Listings that present a potential for development.

Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Commercial Investment Opportunity in Bell, Florida
$269,900
4,844 SF

Commercial Investment Opportunity in Bell, Florida

Versatile commercial building with income potential in a high-traffic location.

3280 Powers Ave, Bell, FL 32619
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Highway Frontage Commercial Building Opportunity
$450,000
3,102 SF

Highway Frontage Commercial Building Opportunity

Versatile commercial building on US HWY 129 in Bell, FL.

829 Main St, Bell, FL 32619
View details
Steinhatchee Landing Resort Commercial Space
$750,000
3,616 SF

Steinhatchee Landing Resort Commercial Space

Commercial space in Steinhatchee Landing Resort, ideal for events.

219 Hwy 51, Steinhatchee, FL 32359
View details
Commercial Property with Living Quarters
$799,000
10,670 SF

Commercial Property with Living Quarters

Turn-key commercial space with office, retail, shop, and apartment.

105 SE Fifteenth Street, Steinhatchee, FL 32359
View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Prime Land in Growing Corridor
$1,795,000
2.07 Acres

Prime Land in Growing Corridor

2.07 acres of PUD-zoned land on State Hwy 207.

3229 State Road 207, Elkton, FL 32033
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Commercial Land on Busy Roadway
$750,000
0.72 Acres

Commercial Land on Busy Roadway

Prime commercial land with high visibility and development potential.

5355 TURNPIKE FEEDER ROAD, Fort Pierce, FL 34945
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Explore Off-Market Properties in Mayo, FL

Consider similar Off-Market properties in Mayo, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

172 Main St

172 Main St

RETAIL STORES (PERSONAL SERVICES) • 8,028 SF
Value Estimation by Request
172 Main St, Mayo, FL 32066-4095
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123 Lynwood Dr

123 Lynwood Dr

RETAIL STORES (PERSONAL SERVICES) • 4,200 SF
Value Estimation
$545,000
123 Lynwood Dr, Mayo, FL 32066-5607
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153 Main St

153 Main St

RETAIL STORES (PERSONAL SERVICES) • 1,995 SF
Value Estimation by Request
153 Main St, Mayo, FL 32066-4035
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263 Main St

263 Main St

RETAIL STORES (PERSONAL SERVICES) • 2,091 SF
Value Estimation by Request
263 Main St, Mayo, FL 32066
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130 Monroe Ave

130 Monroe Ave

RETAIL STORES (PERSONAL SERVICES) • 1,276 SF
Value Estimation by Request
130 Monroe Ave, Mayo, FL 32066-4710
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185 Main St

185 Main St

RETAIL STORES (PERSONAL SERVICES) • 3,851 SF
Value Estimation by Request
185 Main St, Mayo, FL 32066-4808
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158 Fletcher Ave

158 Fletcher Ave

RETAIL STORES (PERSONAL SERVICES) • 600 SF
Value Estimation by Request
158 Fletcher Ave, Mayo, FL 32066
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224 Main St

224 Main St

RETAIL STORES (PERSONAL SERVICES) • 3,840 SF
Value Estimation by Request
224 Main St, Mayo, FL 32066
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222 Main St

222 Main St

RETAIL STORES (PERSONAL SERVICES) • 2,648 SF
Value Estimation by Request
222 Main St, Mayo, FL 32066
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224 Park St

224 Park St

Individual retail properties • 1,080 SF
Value Estimation by Request
224 Park St, Mayo, FL 32066
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845 Us 27

845 Us 27

RETAIL STORES (PERSONAL SERVICES) • 3,342 SF
Value Estimation by Request
845 Us 27, Mayo, FL 32066-5730
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166 Main St

166 Main St

RETAIL STORES (PERSONAL SERVICES) • 4,535 SF
Value Estimation by Request
166 Main St, Mayo, FL 32066
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198 Main St

198 Main St

RETAIL STORES (PERSONAL SERVICES) • 1,089 SF
Value Estimation by Request
198 Main St, Mayo, FL 32066
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214 Main St

214 Main St

RETAIL STORES (PERSONAL SERVICES) • 5,286 SF
Value Estimation by Request
214 Main St, Mayo, FL 32066
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270 Main St

270 Main St

RETAIL STORES (PERSONAL SERVICES) • 2,392 SF
Value Estimation by Request
270 Main St, Mayo, FL 32066
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246 Main St

246 Main St

RETAIL STORES (PERSONAL SERVICES) • 3,116 SF
Value Estimation by Request
246 Main St, Mayo, FL 32066
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597 Main St

597 Main St

RETAIL STORES (PERSONAL SERVICES) • 3,000 SF
Value Estimation by Request
597 Main St, Mayo, FL 32066
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229 Main St

229 Main St

RETAIL STORES (PERSONAL SERVICES) • 1,854 SF
Value Estimation by Request
229 Main St, Mayo, FL 32066
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300 Clyde Ave

300 Clyde Ave

RETAIL STORES (PERSONAL SERVICES) • 9,964 SF
Value Estimation by Request
300 Clyde Ave, Mayo, FL 32066-4614
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Mayo, FL Retail Space Investment Opportunities Market Analysis

Explore 20 retail space for sale in Mayo, FL on our real estate platform. These investment opportunities span a total of 125,018 square feet of properties for sale, with an estimated market value of $1,405,000.

Sale prices for retail space in Mayo, FL start at $545,000, averaging $702,500, and reaching up to $860,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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