Mayo, FL Commercial Real Estate for Sale

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9 properties
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Row-Crop Farm With Irrigation Well
Updated: Jun 26
Row-Crop Farm With Irrigation Well

4844 N CR 53, Mayo, FL 32066

$570,000
75.04 AC lot
75.04 acres currently used for row‑crop farming
Road frontage on three sides
Irrigation well on the property; tenant‑owned pump, pivot, and irrigation equipment are excluded
Currently under lease to a tenant farmer for the next few years
Mostly flat topography; no flood zone or designated wetlands per FEMA maps
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Office Building
Updated: Sep 8, 2025
Office Building

130 NE Clyde Avenue, Mayo, FL 32066

$860,000
1.46 AC lot
1.46‑acre office property in Mayo, Florida
2019 construction with brick exterior
CG zoning
High ceilings and solid‑surface counters
Central heating and central air conditioning
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Wooded Agricultural Land
Wooded Agricultural Land

SW GRACELAND RD., Mayo, FL 32066

$126,000
18.10 AC lot

A-3-zoned rural tract with wooded cover and access near a paved road.

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Established RV Park with 28 Sites
Established RV Park with 28 Sites

165 Se County Road 355, Mayo, FL 32066

$1,100,000
842 sqft

RV property includes additional residential units and shared laundry facilities for occupants.

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Agricultural Land with Natural Landscape
Agricultural Land with Natural Landscape

464 NE Morning Glory Rd., Mayo, FL 32066

$300,000
43.44 AC lot

Mostly natural rural acreage without existing improvements, offering a flexible tract in Lafayette County.

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Mixed-Use Property with Open Space
Mixed-Use Property with Open Space

4485 N COUNTY RD 53, Mayo, FL 32066

Contact for pricing
2,624 sqft

Single-unit office property offering a large open interior with residential and commercial use options.

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Corner Land Parcel For Sale
Corner Land Parcel For Sale

939 NW HAROLD WINBURN RD, Mayo, FL 32066

$4,500,000

Corner land parcel available west of Mayo on HWY 27.

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Farmland with Irrigation Improvements
Farmland with Irrigation Improvements

8619 W Us 27, Mayo, FL 32066

$2,370,000

Agricultural property with farm buildings, commercial wells, and established irrigation infrastructure for crop or pasture operations.

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Planted Pine Agricultural Land
Planted Pine Agricultural Land

123 NW Longitude RD, Mayo, FL 32066

Contact for pricing

Planted pine land with storm damage and potential for clearing or replanting.

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Based on your search, we've compiled 76 Potential Opportunities for your consideration. Besides 9 Active listings in Mayo, FL, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 63 Off-Market properties to explore as potential leads

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Two-Building Manufacturing Property
Two-Building Manufacturing Property

16936 CR 252, Mcalpin, FL 32062

$1,247,000
7,440 sqft 3.03 AC lot

A 3.03-acre operation combines production areas, offices, mezzanine storage, and covered equipment space.

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Renovated Farm With Two Homes
Renovated Farm With Two Homes

19520 168TH STREET, Live Oak, FL 32060

$899,000
2,868 sqft

Fenced rural acreage includes updated residences, pasture, timber, a pond, barns, and agricultural outbuildings.

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A-1 Agricultural Land with Pond
A-1 Agricultural Land with Pond

178TH ST, Live Oak, FL 32060

$536,000
65.00 AC lot

Wooded agricultural acreage with mature hardwoods, pines, and a small pond near the river.

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Wooded Acreage
Wooded Acreage

N CR 349, Mcalpin, FL 32062

$99,900
10.92 AC lot

A1-zoned land with wooded cover and access at both ends of the property.

View details

Off-Market Properties in Mayo, FL

Consider similar Off-Market properties in Mayo, FL. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

305 Main St
VEHICLE SALES, RENTALS

305 Main St, Mayo, FL 32066-4036

Estimated value:
$65,000
2,471 sqft
View details
172 Main St
RETAIL STORES (PERSONAL SERVICES)

172 Main St, Mayo, FL 32066-4095

Estimated value:
$75,000
8,028 sqft
View details
530 Fletcher Ave
RESTAURANT

530 Fletcher Ave, Mayo, FL 32066-4907

Estimated value:
$80,000
3,344 sqft
View details
294 Main St
GROCERY, SUPERMARKET

294 Main St, Mayo, FL 32066

Estimated value:
$445,000
12,351 sqft
View details
224 Clyde Ave
NURSERY, GREENHOUSE, FLORIST

224 Clyde Ave, Mayo, FL 32066

Estimated value:
$145,000
1,975 sqft
View details
Main St
VACANT COMMERCIAL LAND

Main St, Mayo, FL 32066

Estimated value:
$125,000
View details
8540 Main St
WHOLESALE OUTLET, DISCOUNT STORE

8540 Main St, Mayo, FL 32066

Estimated value:
$575,000
16,400 sqft 2.11 AC lot
View details
325 Main St
STORE/OFFICE (MIXED USE)

325 Main St, Mayo, FL 32066

Estimated value: by Request
3,024 sqft
View details
757 State Rd 51
OFFICE BUILDING

757 State Rd 51, Mayo, FL 32066-6609

Estimated value:
$2,200,000
646 sqft 8.10 AC lot
View details
116 Clark Ave
STORE/OFFICE (MIXED USE)

116 Clark Ave, Mayo, FL 32066

Estimated value: by Request
1,535 sqft
View details
253 Bloxham St
MANUFACTURING (LIGHT)

253 Bloxham St, Mayo, FL 32066

Estimated value: by Request
3,072 sqft
View details
968 State Rd 51
VEHICLE SALES, RENTALS

968 State Rd 51, Mayo, FL 32066-6611

Estimated value: by Request
5,298 sqft 3.45 AC lot
View details
536 Nwnw Cir
VACANT COMMERCIAL LAND

536 Nwnw Cir, Mayo, FL 32066

Estimated value:
$180,000
5.00 AC lot
View details
4485 County Rd 53
OFFICE BUILDING

4485 County Rd 53, Mayo, FL 32066-2834

Estimated value: by Request
4,296 sqft
View details
152 Main St
STORE/OFFICE (MIXED USE)

152 Main St, Mayo, FL 32066

Estimated value:
$150,000
8,400 sqft
View details

Mayo, FL Commercial Real Estate Market Trends and Statistics

Explore 72 commercial real estate for sale in Mayo, FL, showcased through 9 active listings on our real estate platform. These investment opportunities span a total of 3,466 square feet of properties for sale, with an estimated market value of $9,826,000.

Sale prices for business properties in Mayo, FL start at $126,000, averaging $1,403,714, and reaching up to $4,500,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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Demographics Overview

Population 6,881
Population Growth (5Y) -10.2%
Median Household Income $61,650
College Educated 11.5%

High-Yield Neighborhoods for Investment

Identify Mayo submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

Neighborhood Average Price
32066 $1.4M

Taxes & Financing

Tax Rate (average for all types) 1.96%
Property Tax per SF $20.50 per SF
Average Loan-to-Value 65.0%

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