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    Wise County, VA Retail Properties & Spaces for Lease

    12 results
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    Commercial Property in Big Stone Gap
    $350,000
    1,400 SF

    Commercial Property in Big Stone Gap

    1809 E 2nd Avenue, Big Stone Gap, VA 24219

    Prominent corner lot suitable for retail or light industrial use.

    • Prominent corner location visible to traffic entering town from US 19.
    • Nearly an acre of fenced land suitable for various uses.
    • Potential for re‑use as convenience retail or light industrial.
    • Existing buildings have utility for service and repair businesses.
    • Office building can be renovated for retail display.
    Updated: Dec 29, 2025
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    Commercial Space in Big Stone Gap
    $259,900
    1,400 SF

    Commercial Space in Big Stone Gap

    11 N 5th Street, Big Stone Gap, VA 24219

    Versatile commercial space suitable for various businesses in Big Stone Gap.

    • Prime location in the heart of Big Stone Gap with high traffic and event exposure.
    • Versatile open floor plan suitable for various business types (salon, office, cafe, restaurant, etc.).
    • Functional drive‑thru window, ideal for restaurant use.
    • Ample parking space available.
    • Modern construction (built in 2017) with durable brick, concrete, and vinyl siding exterior, and metal roof.
    Updated: Aug 8, 2025
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    Restaurant Opportunity in Big Stone Gap
    $400,000
    2,359 SF

    Restaurant Opportunity in Big Stone Gap

    Former Dairy Queen location with drive-thru in downtown Big Stone Gap.

    516 E 5th St N, Big Stone Gap, VA 24219
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    Outparcel for Lease or Sale
    $25,000

    Outparcel for Lease or Sale

    0.50 acre outparcel available for lease or sale.

    16427 Wise Street, Saint Paul, VA 24283
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    Retail Space in Stonewall Square
    Contact for pricing
    3,200 SF

    Retail Space in Stonewall Square

    Retail space available in Lexington, Virginia's Stonewall Square shopping mall.

    121-181 Plaza Rd SW, Wise, VA
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    Retail Space in Ridgeview Centre
    Contact for pricing
    11,608 SF

    Retail Space in Ridgeview Centre

    Retail space available in a busy Wise, Virginia shopping center.

    129 Ridge Circle, Wise, VA 24293
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    Big Stone Gap Retail Center
    Contact for pricing
    18,764 SF

    Big Stone Gap Retail Center

    Retail and office spaces available in Big Stone Gap, Virginia.

    1937-1957 Neeley Rd, Big Stone Gap, VA
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    Retail Spaces Available on Main
    $7 SF/Yr
    4,400 SF

    Retail Spaces Available on Main

    Two retail spaces available for lease on Main Street.

    730 W Main St, Appalachia, VA
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    Commercial Space in Coeburn, VA
    $3,500 /Mo
    8,297 SF

    Commercial Space in Coeburn, VA

    Large commercial space with warehouse storage in Coeburn, Virginia.

    213 E Front Street, Coeburn, VA 24230
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    Historic Retail Space in Coeburn
    $3,500 /Mo

    Historic Retail Space in Coeburn

    Unique retail space with historical significance in Coeburn, Virginia.

    417 E Front Street, Coeburn, VA 24230
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    Retail and Office Space Available
    Contact for pricing
    32,236 SF

    Retail and Office Space Available

    Retail and office opportunities in growing Wise, Virginia.

    181 Plaza Rd SW, Wise, VA 24293
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    Powell Valley Shopping Center Space
    Contact for pricing
    20,000 SF

    Powell Valley Shopping Center Space

    Retail and office spaces available in Big Stone Gap, Virginia.

    1941 Neeley Rd, Big Stone Gap, VA 24219
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    Based on your search, we've compiled 33 Potential Opportunities for your consideration. Besides 12 Active listings in Wise County, VA, we suggest exploring alternatives. Similar 17 Properties for Sales.

    Explore Similar Spaces for Sale in Wise County, VA

    Consider Similar Space for Sale. We found 17 Spaces matching your search parameters.

    Mixed-Use Property in Wise, Virginia
    $350,000
    4,482 SF

    Mixed-Use Property in Wise, Virginia

    Retail space with apartments in the heart of Wise.

    528 W Main Street, Wise, VA 24293
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    Car Wash Investment Opportunity
    $795,000
    3,822 SF

    Car Wash Investment Opportunity

    Car wash with income potential in Wise, Virginia.

    123 WOODLAND DR, Wise, VA 24293
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    Coeburn Multifamily Investment Opportunity
    $1,000,000
    10,000 SF

    Coeburn Multifamily Investment Opportunity

    Four properties with immediate income and significant upside potential.

    207 NE Diagonal Avenue, Coeburn, VA 24230
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    Award-Winning Restaurant with Rental Income
    $229,000
    4,000 SF

    Award-Winning Restaurant with Rental Income

    Turn-key restaurant with rental income in historic Appalachia, Virginia.

    516 W Main Street, Appalachia, VA 24216
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    Wise, VA Opportunity Zone Land
    $325,000

    Wise, VA Opportunity Zone Land

    Land in Wise's retail corridor, ideal for retail/flex development.

    SW Woodland Drive, Wise, VA 24293
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    Mixed-Use Property in Wise, Virginia
    $350,000
    2,462 SF

    Mixed-Use Property in Wise, Virginia

    Commercial space with apartments in the heart of Wise.

    528 W Main Street, Wise, VA 24293
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    Turnkey Commercial Space in Coeburn
    $275,000
    3,600 SF

    Turnkey Commercial Space in Coeburn

    Versatile 3,600 sqft commercial space suitable for various businesses.

    118 NE Grand Avenue, Coeburn, VA 24230
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    Refreshed Commercial Building in St. Paul
    $59,900
    1,000 SF

    Refreshed Commercial Building in St. Paul

    Newly refreshed commercial building in the heart of St. Paul.

    16557 Broad Street, Saint Paul, VA 24283
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    Commercial Property in Downtown Wise
    $475,000
    8,900 SF

    Commercial Property in Downtown Wise

    2.088 acres with retail space and development potential.

    119 NW Independence Avenue, Wise, VA 24293
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    Mixed-Use Property in Appalachia, VA
    $115,000
    7,164 SF

    Mixed-Use Property in Appalachia, VA

    Commercial and residential spaces with rental income potential in Appalachia.

    106 Kentucky Avenue unit: A, Appalachia, VA 24216
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    Coeburn Commercial Unit For Sale
    $35,500
    675 SF

    Coeburn Commercial Unit For Sale

    675 SF commercial unit in Coeburn Business Building.

    340 E Front Street, Coeburn, VA 24230
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    Family Dollar Leased Investment Property
    $1,491,750
    8,400 SF

    Family Dollar Leased Investment Property

    NNN leased investment property with long-term tenant.

    202 FRONT ST, Coeburn, VA 24230
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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Paved Lot on Highway 23
    $4,739 /Mo

    Paved Lot on Highway 23

    Large paved lot for lease on busy Highway 23.

    923 Hwy 23, Weber City, VA 24290
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    Prime Commercial Land For Lease
    Contact for pricing

    Prime Commercial Land For Lease

    1.57 acre outparcel ground lease in high-traffic area.

    731 US-11W, Church Hill, TN 37642
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    Restaurant Pad Near Eastman Chemical
    Contact for pricing

    Restaurant Pad Near Eastman Chemical

    Restaurant pad site near Eastman Chemical, Meadowview Convention Center.

    Southgate Place & S Wilcox Drive, Kingsport, TN
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    Prime Commercial Land For Lease
    Contact for pricing

    Prime Commercial Land For Lease

    1.57 acre outparcel in high-traffic area, Church Hill.

    731 Highway 11 W, Church Hill, TN
    View details

    Wise County, VA Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in Wise County, VA with 12 listings featured on our commercial real estate exchange. The current inventory includes 370,129,320 square feet of properties with an estimated lease value of $215 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in Wise County, VA begin at $5 SF/Yr, with an average of $107 SF/Yr and extend to $210 SF/Yr.
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    Retail properties & Spaces by market

    Browse Retail properties & Spaces for Lease Near Wise, VA

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