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    Clayton, MO Retail Properties & Spaces for Lease

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    14 results
    Former Bank Building For Sale
    Contact for pricing
    7,200 SF

    Former Bank Building For Sale

    6369 Clayton Rd, Clayton, MO

    7,200 SF building on 0.64 acre in Clayton, MO.

    • Prime location at the signalized intersection of Clayton Rd & DeMun Ave, offering high visibility and accessibility.
    • 7,200 SF building with 4 drive‑thru lanes, suitable for various commercial uses.
    • Zoned C‑2 General Commercial, Clayton Road Urban Design District in the City of Clayton, providing flexible development options.
    • Directly across the street from SSM St. Mary’s Hospital, a major traffic generator.
    • Full unfinished basement, offering potential for additional space and customization.
    Updated: Nov 25, 2025
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    New Retail Space in Clayton
    Contact for pricing
    2,126 SF

    New Retail Space in Clayton

    33 N Central Ave, Clayton, MO

    New retail space in mixed-use development with high foot traffic.

    • Newly constructed mixed‑use project with 120 luxury apartments (98% leased) and 13,585 SF of retail space.
    • Centrally located in Clayton, St. Louis County's central business district.
    • High daytime population of 52,841 people.
    • Located within an area with over 8 Million square feet of prestigious office space.
    • Sidewalk widened to accommodate outdoor seating.
    Updated: Nov 24, 2025
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    Versatile Retail Space Available
    $23 SF/Yr
    6,774 SF

    Versatile Retail Space Available

    Adaptable space suitable for various business ventures.

    8-16 N Meramec Ave, Clayton, MO
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    Downtown Clayton Retail/Restaurant Space
    Contact for pricing
    2,400 SF

    Downtown Clayton Retail/Restaurant Space

    Prime location with open ceilings and polished concrete floors.

    16 N Central Ave, Clayton, MO
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    Renovated Office Space in Clayton
    $26 SF/Yr
    1,993 SF

    Renovated Office Space in Clayton

    Multiple suites available in a recently renovated building.

    7711 Bonhomme Ave, Clayton, MO
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    Clayton Retail/Restaurant Space Available
    Contact for pricing
    3,484 SF

    Clayton Retail/Restaurant Space Available

    Premier retail and restaurant space in Clayton, Missouri.

    8027 Forsyth Blvd, Clayton, MO
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    Downtown Clayton Retail Space Available
    $35 SF/Yr
    3,500 SF

    Downtown Clayton Retail Space Available

    Prominent corner location near restaurants and government amenities.

    7931 Forsyth Blvd, Clayton, MO
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    Forsyth Blvd Office Space Available
    $45 SF/Yr
    20,000 SF

    Forsyth Blvd Office Space Available

    Office space available with covered parking and modern amenities.

    7676 Forsyth Blvd, Clayton, MO
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    Forsyth Boulevard Commercial Space
    Contact for pricing

    Forsyth Boulevard Commercial Space

    Commercial space available for lease on Forsyth Boulevard.

    8027 Forsyth Blvd, Clayton, MO 63105
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    Downtown Clayton Retail Space Available
    $30 SF/Yr
    1,330 SF

    Downtown Clayton Retail Space Available

    Prime retail location with high visibility and foot traffic.

    12-16 S Bemiston Ave, Clayton, MO
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    Class A+ Office Tower
    $42 SF/Yr
    1,336 SF

    Class A+ Office Tower

    15-story office tower with high-end finishes and convenient access.

    1 N Brentwood Blvd, Clayton, MO
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    Retail Space in Clayton Neighborhood
    $30 SF/Yr
    1,837 SF

    Retail Space in Clayton Neighborhood

    Boutique retail or spa space in a prime location.

    7651 Clayton Rd, Clayton, MO
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    Downtown Clayton Retail Space Available
    Contact for pricing
    1,330 SF

    Downtown Clayton Retail Space Available

    1,330 SF retail space in downtown Clayton.

    14 South Bemiston Ave, Clayton, MO 63105
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    Retail Space in Clayton
    Contact for pricing
    1,837 SF

    Retail Space in Clayton

    Single tenant retail space available for rent in Clayton.

    Clarendale Clayton, Clayton, MO 63117
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    Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 14 Active listings in Clayton, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Explore Retail properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office Space with Car Wash
    $28 SF/Yr
    12,955 SF

    Office Space with Car Wash

    Office space for rent with on-site amenities.

    7711 CARONDELET AVE, Saint Louis, MO
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    Delmar Loop Retail Space
    Contact for pricing
    2,070 SF

    Delmar Loop Retail Space

    Retail space in vibrant Delmar Loop, University City.

    6662 Delmar Blvd, University City, MO
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    Restaurant Space on Delmar Boulevard
    Contact for pricing
    5,218 SF

    Restaurant Space on Delmar Boulevard

    Second-generation restaurant space with frontage on Delmar Boulevard.

    6255-6300 Delmar Blvd, University City, MO
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    Prime Retail Space in St. Louis
    Contact for pricing

    Prime Retail Space in St. Louis

    Located in the heart of the St. Louis metro area.

    Saint Louis, MO 63117
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    Explore Similar Spaces for Sale in Clayton, MO

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Clayton Road Retail Opportunity
    $5,995,000
    8,500 SF

    Clayton Road Retail Opportunity

    Retail and office spaces available in prime Clayton location.

    8211-8221 Clayton Rd, Clayton, MO
    View details
    Clayton Road Commercial Property For Sale
    $1,900,000
    7,200 SF

    Clayton Road Commercial Property For Sale

    Commercial property available for sale on Clayton Road.

    6369 Clayton Rd, Clayton, MO 63117
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Vacant Land Near I-44
    $225,000

    Vacant Land Near I-44

    10.11 acres of vacant land with I-44 visibility.

    800 S Highway, Fenton, MO 63026
    View details
    Collinsville Commercial Space For Lease
    $5,000 /Mo
    5,000 SF

    Collinsville Commercial Space For Lease

    Versatile commercial space in Collinsville, available immediately.

    1902 Vandalia Street, Collinsville, IL 62234
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    Cleared Lot in St Clair
    $1.00 SF/Yr

    Cleared Lot in St Clair

    1.5-acre cleared lot zoned for general commercial use.

    Saint Clair, MO 63077
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    High-Traffic Commercial Land in Rolla
    $7,500 /Mo

    High-Traffic Commercial Land in Rolla

    0.61 acre commercial land in high-traffic area for lease.

    704 N Bishop Avenue, Rolla, MO 65401
    View details

    Clayton, MO Retail properties & Spaces Leasing Opportunities Market Analysis

    Explore Retail properties & Spaces leasing options in Clayton, MO with 14 listings featured on our commercial real estate exchange. The current inventory includes 1,428,985,800 square feet of properties with an estimated lease value of $179 SF/Yr.

    Estimated lease rates for Retail properties & Spaces in Clayton, MO begin at $26 SF/Yr, with an average of $35 SF/Yr and extend to $45 SF/Yr.
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    Most Searched ZIP Codes in Clayton, MO

    • 63105
    • 63117

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