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Lexington County, SC Office Space for Lease

151 results
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Versatile Commercial Space in West Columbia
$4,800 / Mo
23,087 SF

Versatile Commercial Space in West Columbia

818 Williams St, West Columbia, SC 29169

Functional warehouse and office space with mezzanine, ideal for various uses.

  • Over 10,000 SF of functional space at an exceptional value.
  • LM zoning allows for a wide range of uses.
  • Versatile property combining warehouse functionality with finished office space.
  • Upstairs mezzanine (1,064 SF) framed and wired, ready to be finished.
  • Two sliding bay doors (15' wide and 13' high) and 14' clear ceiling height in the warehouse.
Updated: Dec 22, 2025
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Lady Street Creative Office Suites
$24 SF/Yr
11,372 SF

Lady Street Creative Office Suites

911 Lady St, Columbia, SC 29201

Downtown Vista: Stylish Office Space

  • Two renovated, first‑floor suites available for lease in Columbia's Vista District.
  • Totaling 11,372 square feet, with suites divisible down to 723 square feet. Maximum contiguous space is 1,616 square feet.
  • Features exposed brick and ductwork, ideal for creative office or retail use.
  • Suite D offers approximately 1,616 square feet with three dedicated parking spaces, while Suite E offers approximately 723 square feet with one dedicated parking space.
  • Lease rate: $24.00 per square foot, net of janitorial.
Updated: Dec 11, 2024
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Lady Street Creative Office Space
$16 SF/Yr
7,500 SF

Lady Street Creative Office Space

±3,300 SF Vista District Office

721 Lady St, Columbia, SC 29201
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Airport Square Office Complex
$9 SF/Yr
58,207 SF

Airport Square Office Complex

Prime Office Space, Multiple Uses

1618 Airport Blvd, West Columbia, SC 29169
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Executive Office Suites Columbia SC
$13 SF/Yr
27,343 SF

Executive Office Suites Columbia SC

Prime Columbia office space, multiple suites available.

3790 Fernandina Rd, Columbia, SC 29210
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Landmark IV Office Suites
Contact for pricing
69,349 SF

Landmark IV Office Suites

Columbia, SC Class A Office Space

3710 Landmark Dr, Columbia, SC 29204
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Landmark I Office Suites
Contact for pricing
70,704 SF

Landmark I Office Suites

Columbia, SC Office Space Available

3600 Forest Dr, Columbia, SC 29204
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Westpark Boulevard Office Space
$18 SF/Yr
49,138 SF

Westpark Boulevard Office Space

Columbia, SC Executive Office Suites Available

107 Westpark Blvd, Columbia, SC 29210
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Cottontown Retail/Office Space
$14 SF/Yr
4,500 SF

Cottontown Retail/Office Space

±4,500 SF, Modernized Building, Great Location

2222 Sumter St, Columbia, SC 29201
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Stoneridge Executive Office Space
$18 SF/Yr
108,000 SF

Stoneridge Executive Office Space

Class A Office Suites in Columbia, SC

140 Stoneridge Dr, Columbia, SC 29210
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Brentwood at Forest Drive: Creative Office Space
$33 SF/Yr
14,660 SF

Brentwood at Forest Drive: Creative Office Space

New Columbia, SC Creative Office Suites

1514 Brentwood Dr, Columbia, SC 29206
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Office/Warehouse Space For Rent
$8 SF/Yr
10,860 SF

Office/Warehouse Space For Rent

10,860 SF office/warehouse space with excellent I-26 access.

207 Beaufort St, Chapin, SC 29036
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Desirable Office Space For Rent
$25 SF/Yr
10,000 SF

Desirable Office Space For Rent

Office space in Forest Acres market, close to health campuses.

1777 St Julian Pl, Columbia, SC
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Office Space in Columbia, SC
Contact for pricing
8,518 SF

Office Space in Columbia, SC

Office space available for lease in Columbia, South Carolina.

115 Blarney Dr, Columbia, SC 29223
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Class-A Office/Medical Space Available
$22 SF/Yr
3,100 SF

Class-A Office/Medical Space Available

Class-A office/medical space for lease in Northeast Columbia.

1074 Pinnacle Point Dr, Columbia, SC 29223
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Office & Retail Space Available
$25 SF/Yr
2,415 SF

Office & Retail Space Available

Office and retail spaces available in Columbia, South Carolina.

600 Canalside St, Columbia, SC 29201
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Office Space Near Downtown Columbia
Contact for pricing
2,025 SF

Office Space Near Downtown Columbia

2,025 SF office space with easy interstate access.

245 Stoneridge Dr, Columbia, SC 29210
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Former Dental Clinic For Rent
$291,500
2,915 SF

Former Dental Clinic For Rent

2,915 SF former dental clinic available for rent.

392 Saint Andrews Rd, Columbia, SC 29210
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Premium Commercial Office Space
$22 SF/Yr
684 SF

Premium Commercial Office Space

Professional office space in a bustling business district.

3200 Devine St, Columbia, SC 29205
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Highland Center Office Space Available
$21 SF/Yr
7,000 SF

Highland Center Office Space Available

Office and medical space available for lease in Columbia.

122 Highland Center Dr, Columbia, SC 29203
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Downtown Columbia Office Space Available
$25 SF/Yr
2,500 SF

Downtown Columbia Office Space Available

Office space for rent in downtown Columbia's Central Business District.

930 Richland St, Columbia, SC 29201
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Columbia Office Space for Rent
Contact for pricing
3,037 SF

Columbia Office Space for Rent

Energy star-certified office space with modernized lobbies and free parking.

101 Executive Center Dr, Columbia, SC 29210
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Office Space for Small Business
$17 SF/Yr
725 SF

Office Space for Small Business

Office suite ideal for a small professional business.

1735 Saint Julian Pl, Columbia, SC 29204
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Renovated Office Space on Harden
$1,500 / Mo
1,000 SF

Renovated Office Space on Harden

Newly renovated office space with ample natural light available for rent.

1310 Harden St, Columbia, SC 29204
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Lexington County, SC Office space Leasing Opportunities Market Analysis

Explore Office space leasing options in Lexington County, SC with 185 listings featured on our commercial real estate exchange. The current inventory includes 40,565,676,922 square feet of properties with an estimated lease value of $2,089 /Mo.

Estimated lease rates for Office space in Lexington County, SC begin at $2 SF/Yr, with an average of $18 SF/Yr and extend to $70 SF/Yr.
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