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    Onondaga County, NY Office Space for Lease

    107 results
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    Downtown Syracuse Office Space Available
    $10,000 / Mo
    39,245 SF

    Downtown Syracuse Office Space Available

    344 W Genesee St, Syracuse, NY 13202

    Prime downtown Syracuse office space with parking available for lease.

    • Prime downtown Syracuse office space.
    • 50‑car parking included.
    • Multiple suites available, some turnkey ready.
    • Suites can be combined for larger space to meet your needs.
    • Large windows with city views.
    Updated: Oct 29, 2025
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    Versatile Commercial Space in Syracuse
    $500 / Mo
    1,500 SF

    Versatile Commercial Space in Syracuse

    1807 W Genesee St, Syracuse, NY 13204

    Bright commercial space ideal for offices, studio, or retail.

    • High‑traffic, easily accessible location with excellent visibility.
    • Flexible leasing options: entire space ($1,650/month) or individual offices ($500/month).
    • Four private offices/spaces suitable for various business types.
    • Beautiful hardwood floors throughout the space.
    • Convenient access to major routes, restaurants, and shopping.
    Updated: Nov 5, 2025
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    East Syracuse Commercial Space Available
    $1,900 / Mo
    14,506 SF

    East Syracuse Commercial Space Available

    Class A office space in desirable East Syracuse location.

    5710 Commons Park, East Syracuse, NY 13057
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    Cicero, NY Office Space Available
    $12 SF/Yr
    11,039 SF

    Cicero, NY Office Space Available

    Versatile Office Space, Prime Location

    5620 Business Ave, Cicero, NY 13039
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    Green Hills Plaza: Lease Opportunity
    $6 SF/Yr
    70,696 SF

    Green Hills Plaza: Lease Opportunity

    Versatile spaces, prime Onondaga location.

    5957-6003 Salina St, Syracuse, NY 13205
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    Syracuse Creative Office Space
    $17 SF/Yr
    40,000 SF

    Syracuse Creative Office Space

    Modern Office Suites, Flexible Sizes

    100 Elwood Davis Rd, Syracuse, NY 13212
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    One Park Place: Premier Office Space
    $18 SF/Yr
    300,000 SF

    One Park Place: Premier Office Space

    Class A Office Suites, 2,500-80,000 SF

    300 State St, Syracuse, NY 13202
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    Prime North Syracuse Office Space
    $15 SF/Yr
    21,160 SF

    Prime North Syracuse Office Space

    Modern Office Suites, Flexible Sizes Available

    7293 Buckley Rd, North Syracuse, NY 13212
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    Armory Square Office Space Available
    $22 SF/Yr
    30,000 SF

    Armory Square Office Space Available

    Syracuse, NY: Prime Office & Retail Space

    183 Walton St, Syracuse, NY 13202
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    Herald Place Office Space for Lease
    $225 SF/Yr
    1,600 SF

    Herald Place Office Space for Lease

    Updated 1,600 sq ft Office in Syracuse

    221 Herald Pl, Syracuse, NY 13202
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    Downtown Syracuse Office Space
    $180 SF/Yr
    3,000 SF

    Downtown Syracuse Office Space

    Prime 3,000 sq ft Office in Syracuse, NY

    216 Genesee St, Syracuse, NY 13202
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    Syracuse Commercial Gem: 3,600 SF
    $4,200 / Mo
    3,600 SF

    Syracuse Commercial Gem: 3,600 SF

    Versatile office space near Route 81.

    2500 Brewerton Rd, Mattydale, NY 13211
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    Professional Office Space Available
    $16 SF/Yr
    2,029 SF

    Professional Office Space Available

    2,029 SF office space with highway and university access.

    3125 East Genesee St, Syracuse, NY 13224
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    Class A Suburban Office Space
    $18 SF/Yr
    53,992 SF

    Class A Suburban Office Space

    Class A office space available for rent in Syracuse, NY.

    231 Salina Meadows Pkwy, Syracuse, NY 13212
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    Class A Suburban Office Park
    $18 SF/Yr
    44,730 SF

    Class A Suburban Office Park

    Class A office space for rent in Syracuse, New York.

    200 Salina Meadows Pkwy, Syracuse, NY 13212
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    Class A Suburban Office Space
    $18 SF/Yr
    53,992 SF

    Class A Suburban Office Space

    Class A office space available for rent in Syracuse, NY.

    231 Salina Meadows Pkwy, Syracuse, NY 13212
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    Class A Office Space Syracuse
    $18 SF/Yr
    44,730 SF

    Class A Office Space Syracuse

    Class A office park with amenities in Syracuse, New York.

    220 Salina Meadows Pkwy, Syracuse, NY 13212
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    Available Office Space For Rent
    Contact for pricing
    18,190 SF

    Available Office Space For Rent

    Office space with open layout and excellent location for rent.

    103 Commerce Blvd, Liverpool, NY 13088
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    Downtown Office Space Available
    $15 SF/Yr
    26,000 SF

    Downtown Office Space Available

    Up to 26,000 SF available in downtown Syracuse.

    677 S Salina St, Syracuse, NY 13202
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    Collamer Office Building Space Available
    Contact for pricing
    1,175 SF

    Collamer Office Building Space Available

    Office spaces for rent in a well-maintained building.

    6670 Old Collamer Rd, E Syracuse, NY 13057
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    Renovated Space for Diverse Uses
    $10 SF/Yr
    1,000 SF

    Renovated Space for Diverse Uses

    Adaptable renovated space suitable for retail or office use.

    2105 W Genesee St, Syracuse, NY 13219
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    Manlius Retail/Medical/Office Space Available
    Contact for pricing
    11,149 SF

    Manlius Retail/Medical/Office Space Available

    Former Kinney Drugs space for lease in Manlius, NY.

    7650-7660 Highbridge Rd, Manlius, NY 13104
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    Furnished Office Space Available
    Contact for pricing
    1,895 SF

    Furnished Office Space Available

    Move-in ready office space with flexible lease terms.

    5000 Campuswood Dr, East Syracuse, NY 13057
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    Flexible Office Space Available
    Contact for pricing
    3,800 SF

    Flexible Office Space Available

    Office space with parking, private offices, and convenient location.

    212-210 W Division St, Syracuse, NY 13204
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    Onondaga County, NY Office space Leasing Opportunities Market Analysis

    Explore Office space leasing options in Onondaga County, NY with 127 listings featured on our commercial real estate exchange. The current inventory includes 79,131,531,600 square feet of properties with an estimated lease value of $1,521 /Mo.

    Estimated lease rates for Office space in Onondaga County, NY begin at $1.57 SF/Yr, with an average of $20 SF/Yr and extend to $225 SF/Yr.
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    Browse Office space for Lease Near Onondaga, NY

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