For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Space Uses
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Rent
    Rent / SF / Yr
    $
    $
    Rent / Mo
    $
    $
    Size
    Property size / sq.ft.

    E Syracuse, NY Office Units for Lease

    Notify Me
    List
    Map
    13 results
    East Syracuse Commercial Space Available
    $1,900/Mo
    14,506 SF

    East Syracuse Commercial Space Available

    5710 Commons Park, East Syracuse, NY 13057

    Class A office space in desirable East Syracuse location.

    • Highly desirable location near Widewaters Parkway with easy access to major highways and downtown Syracuse.
    • Gross lease: Landlord pays for heat, air conditioning, and electricity.
    • Impeccably maintained Class A professional building with newly remodeled kitchen and recently painted exterior.
    • Excellent accessibility: One‑story building with no stairs and plenty of free parking.
    • Access to shared restrooms, conference room, and outdoor patio.
    Updated: Dec 30, 2025
    View details
    Pioneer Business Park Office Suite
    $16 SF/Yr
    6,556 SF

    Pioneer Business Park Office Suite

    5009 Campuswood Dr, East Syracuse, NY 13057

    Build-to-suit office suite in a vibrant business park.

    • Build‑to‑suit suite allows customization of workspace.
    • Located in the highly desirable Pioneer Business Park.
    • Features two newly renovated bathrooms.
    • Offers direct views of park's ponds and abundant natural light.
    • Access to Pioneer Business Park amenities including hotels, outdoor patios, picnic areas, and a fitness trail.
    Updated: Nov 21, 2025
    View details
    Office Suite in Quiet Office Park
    Contact for pricing

    Office Suite in Quiet Office Park

    Office suite with private offices, open space, and conference rooms.

    5852 Heritage Landing Drive, East Syracuse, NY 13057
    View details
    Commissary Kitchen on Collamer Road
    Contact for pricing
    1,572 SF

    Commissary Kitchen on Collamer Road

    1,572 SF fully-built commissary kitchen with frontage.

    6491 Collamer Rd, East Syracuse, NY 13057
    View details
    Office and Flex Suites Available
    $12 SF/Yr
    1,283 SF

    Office and Flex Suites Available

    Office and flex suites with drive-in door options available.

    6437 Collamer Rd, E Syracuse, NY
    View details
    E Syracuse Office Space Available
    Contact for pricing
    1,500 SF

    E Syracuse Office Space Available

    25,000 SF building with diverse tenant mix.

    101 Adler Dr, E Syracuse, NY
    View details
    Office/Warehouse Space Available
    Contact for pricing
    6,365 SF

    Office/Warehouse Space Available

    Office and warehouse space with dock and drive-in door.

    7020 Fly Rd, East Syracuse, NY
    View details
    Collamer Office Building Space Available
    Contact for pricing
    1,175 SF

    Collamer Office Building Space Available

    Office spaces for rent in a well-maintained building.

    6670 Old Collamer Rd, E Syracuse, NY
    View details
    Furnished Office Space Available
    Contact for pricing
    1,895 SF

    Furnished Office Space Available

    Move-in ready office space with flexible lease terms.

    5000 Campuswood Dr, East Syracuse, NY
    View details
    New Development Opportunity in Syracuse
    Contact for pricing
    26,000 SF

    New Development Opportunity in Syracuse

    New Class A medical/office or office/warehouse facility for lease.

    6731 Fly Rd, East Syracuse, NY
    View details
    Renovated Retail and Office Space
    Contact for pricing
    17,310 SF

    Renovated Retail and Office Space

    Newly renovated retail and office spaces available for lease.

    7027-7041 Manlius Center Rd, E Syracuse, NY
    View details
    Two-Story Office Building For Rent
    Contact for pricing
    675 SF

    Two-Story Office Building For Rent

    Two-story office building with suites ranging from 440-4,650 square feet.

    6320 Fly Rd, E Syracuse, NY
    View details
    Kirkville Road Medical/Office Suites
    Contact for pricing
    710 SF

    Kirkville Road Medical/Office Suites

    Medical/office suites for lease near I-481 in East Syracuse.

    6700 Kirkville Rd, E Syracuse, NY
    View details
    Based on your search, we've compiled 18 Potential Opportunities for your consideration. Besides 13 Active listings in E Syracuse, NY, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Explore Office Units for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Retail/Office Suites on James Street
    Contact for pricing
    850 SF

    Retail/Office Suites on James Street

    Three suites available with high visibility and modern finishes.

    3001-3023 James St, Syracuse, NY
    View details
    Retail Space on Thompson Road
    Contact for pricing
    9,068 SF

    Retail Space on Thompson Road

    9,068 SF retail, office, and warehouse space for lease.

    6361 Thompson Rd, Syracuse, NY
    View details
    Fayetteville Office Space Available
    Contact for pricing
    2,766 SF

    Fayetteville Office Space Available

    Office space for rent with ample parking and amenities.

    4100 Medical Center Dr, Fayetteville, NY
    View details
    Fayetteville Office Space For Rent
    Contact for pricing
    40,000 SF

    Fayetteville Office Space For Rent

    Office space ideal for medical or professional use near I-690.

    6800 E Genesee St, Fayetteville, NY
    View details

    Explore Similar Spaces for Sale in E Syracuse, NY

    Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

    Manufacturing Warehouse with Office Space
    $2,920,000
    30,000 SF

    Manufacturing Warehouse with Office Space

    30,000 SF manufacturing/warehouse with 8,000 SF office space.

    6250 E Molloy Rd, East Syracuse, NY
    View details

    E Syracuse, NY Office Units Leasing Opportunities Market Analysis

    Explore Office Units leasing options in E Syracuse, NY with 13 listings featured on our commercial real estate exchange. The current inventory includes 22,345 square feet of properties with an estimated lease value of $30 SF/Yr.

    Estimated lease rates for Office Units in E Syracuse, NY begin at $1.57 SF/Yr, with an average of $10 SF/Yr and extend to $16 SF/Yr.
    List
    Map