For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Space Uses
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
Price
Price range
$
$
Size
Property size / sq.ft.

Independence, MO Office Space for Lease

7 results
List
Map
Move-in Ready Office Space Available
$19 SF/Yr
69,696 SF

Move-in Ready Office Space Available

20101 E Jackson. Dr, Independence, MO 64057

Exceptional office space near I-70, ideal for various business needs.

  • Unbeatable location just north of Interstate 70 and one mile east of the I‑70/I‑470 interchange.
  • Move‑in‑ready space with a pristine interior, previously used as an insurance and university office.
  • Easily accessible via the Little Blue Parkway exit ramp and ample parking.
  • Proximity to the Independence Center shopping district and major retailers.
  • Located near the Independence Events Center, drawing consistent foot traffic with over 100 events annually.
Updated: Sep 16, 2025
View details
Built-Out Office Space Available
$14 SF/Yr
1,650 SF

Built-Out Office Space Available

19401 Us-40 E, Independence, MO

Office space with private offices, restroom, and reception area.

  • Fully built out office, ready for immediate occupancy.
  • Features 6 private offices.
  • Includes a private restroom.
  • Welcoming reception area for clients and guests.
  • Convenient break room for staff.
View details
Medical Office Space For Rent
Contact for pricing
5,276 SF

Medical Office Space For Rent

Medical office space with hospital access and ample parking.

19550-19600 E 39Th St S, Independence, MO 64057
View details
Office Spaces Available in 2025
$13 SF/Yr
1,237 SF

Office Spaces Available in 2025

Office spaces for rent with ample parking and updates.

3675 S Noland Rd, Independence, MO 64055
View details
Renovated Office Space Available
$12 SF/Yr
7,575 SF

Renovated Office Space Available

3,000-7,575 SF office space for lease after 2021 renovations.

201 E Partridge Ave, Independence, MO 64055
View details
Office Space Near I-70/I-470
Contact for pricing
2,616 SF

Office Space Near I-70/I-470

Centrally located office space with good highway visibility.

4721-4731 S Cliff Ave, Independence, MO 64055
View details
Office Space with Private Restroom
$10 SF/Yr
1,361 SF

Office Space with Private Restroom

Office space featuring private offices, restroom, and designated storage.

14405 E 42Nd St S, Independence, MO 64055
View details
Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 7 Active listings in Independence, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

Explore Office space for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Office Space in Kansas City
Contact for pricing
13,900 SF

Office Space in Kansas City

13,900 sq ft office space available for rent.

12019 E 47Th St, Kansas City, MO 64133
View details
Blue Vue Shopping Center: KCMO Retail Space
$6 SF/Yr
31,587 SF

Blue Vue Shopping Center: KCMO Retail Space

Prime KCMO retail space, multiple suites available.

4701 Blue Ridge Blvd, Kansas City, MO 64133
View details
Blue Springs Office Space Available
Contact for pricing
1,919 SF

Blue Springs Office Space Available

Office space available for rent in Blue Springs, Missouri.

206 NW Mock Ave, Blue Springs, MO 64014
View details
Blue Springs Office Space Available
Contact for pricing
10,006 SF

Blue Springs Office Space Available

Office space available for rent in Blue Springs, Missouri.

201 NW R D Mize Rd, Blue Springs, MO 64014
View details

Explore Similar Spaces for Sale in Independence, MO

Consider Similar Space for Sale. We found 1 Spaces in Nearby Locations matching your search parameters.

Reformed Office Space in Independence
$119,000
0.13 Acres

Reformed Office Space in Independence

Charming office space in a reformed residential home.

911 E 23Rd St, Independence, MO 64055
View details

Independence, MO Office space Leasing Opportunities Market Analysis

Explore Office space leasing options in Independence, MO with 8 listings featured on our commercial real estate exchange. The current inventory includes 3,550,967,640 square feet of properties with an estimated lease value of $68 SF/Yr.

Estimated lease rates for Office space in Independence, MO begin at $10 SF/Yr, with an average of $13 SF/Yr and extend to $19 SF/Yr.
List
Map