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    St Lucie County, FL Office Space for Lease

    65 results
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    Ocean View Office Suite
    $1,200 / Mo
    4,500 SF

    Ocean View Office Suite

    221 S Ocean Dr, Fort Pierce, FL 34949

    Second-floor office suite with ocean views available for lease.

    • Ocean view office suite
    • Reasonable lease rate for Hutchinson Island location ($1,200/month year 1)
    • New metal roof and impact windows
    • Approximately 1,050 sq ft with entry/conference room + 4 offices + private bathroom
    • Join established businesses (Coldwell Banker, Ryen Marine Insurance Group)
    Updated: Dec 19, 2025
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    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    3801 Oleander Ave, Fort Pierce, FL 34982

    Flexible leasing options in a busy industrial corridor.

    • Modified Gross Lease: Taxes and insurance included in the $17/sq ft rate.
    • Flexible Leasing Options: Multiple 1500 sqft units available for single or multiple space rentals.
    • Move‑in Ready & Versatile: Sleek, modern flex office spaces suitable for a variety of businesses.
    • Private Amenities: Each unit includes a private bathroom, showroom/office space, and warehouse/storage area.
    • Prime Location: Situated on Oleander Avenue, a busy industrial corridor with excellent access to I‑95, US‑1, and the Florida Turnpike.
    Updated: Dec 18, 2025
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    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Flexible leasing options in modern flex office spaces.

    3801 Oleander Ave, Fort Pierce, FL 34982
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    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Modern flex office spaces for lease in Fort Pierce, Florida.

    3801 Oleander Ave, Fort Pierce, FL 34982
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    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Modern flex office spaces for lease on busy industrial corridor.

    3801 Oleander Ave, Fort Pierce, FL 34982
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    Modern Flex Office Spaces Available
    $17 SF/Yr
    1,500 SF

    Modern Flex Office Spaces Available

    Versatile flex spaces on a busy industrial corridor.

    3801 Oleander Ave, Fort Pierce, FL 34982
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    Profitable Office Space with Tenants
    $275,000

    Profitable Office Space with Tenants

    Turnkey office property with long-term tenants and immediate cash flow.

    544 NW University Blvd Blvd, Port Saint Lucie, FL 34986
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    Professional Office Space Available
    $2,287 / Mo
    998 SF

    Professional Office Space Available

    Class A office suite with private offices and open space.

    2100 SE Hillmoor Dr, Port St Lucie, FL 34952
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    Landmark Office Building in Fort Pierce
    $16 SF/Yr
    56,628 SF

    Landmark Office Building in Fort Pierce

    5,400 SF office space available for lease.

    2222 Colonial Rd, Fort Pierce, FL 34950
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    Fort Pierce Office Space Available
    $16 SF/Yr
    18,228 SF

    Fort Pierce Office Space Available

    2,400 SF office space for lease in Fort Pierce.

    2222 Colonial Rd, Fort Pierce, FL 34950
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    Medical Office Space For Rent
    $24 SF/Yr
    998 SF

    Medical Office Space For Rent

    Updated medical office space available for rent in Port St. Lucie.

    1801 SE Hillmoor Dr, Port St Lucie, FL 34952
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    Port St. Lucie Executive Office
    $1,527 / Mo
    998 SF

    Port St. Lucie Executive Office

    Executive office suite in Port St. Lucie medical corridor.

    2100 SE Hillmoor Dr, Port St Lucie, FL 34952
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    Fort Pierce Office/Warehouse Space
    $10,000 / Mo
    4,648 SF

    Fort Pierce Office/Warehouse Space

    Versatile commercial property on US 1 with high visibility.

    3535 Old Dixie Hwy, Fort Pierce, FL 34946
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    Fountain Business Center: Port St. Lucie Offices
    $25 SF/Yr
    18,382 SF

    Fountain Business Center: Port St. Lucie Offices

    New 3-story office building, flexible suites.

    1380 Import Dr, Port St. Lucie, FL 34953
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    Stadium Business Center Office Space
    $17 SF/Yr
    3,000 SF

    Stadium Business Center Office Space

    Creative Office Suites, Port St. Lucie, FL

    590 Peacock Blvd, Port St. Lucie, FL 34986
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    Prime Port St. Lucie Office Space
    $326 / Mo
    1,384 SF

    Prime Port St. Lucie Office Space

    Class A Office, 1384 sq ft, Ideal Location

    2100 Hillmoor Dr, Port St. Lucie, FL 34952
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    Fort Pierce Industrial Space
    $8 SF/Yr
    350,000 SF

    Fort Pierce Industrial Space

    350,000 SF Flex Space, 90,000 SF Available

    4300 Okeechobee Rd, Fort Pierce, FL 34947
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    Prime Medical Office Space, Fort Pierce
    $25 SF/Yr
    2,500 SF

    Prime Medical Office Space, Fort Pierce

    2,500 sq ft, Class A Office, Excellent Location

    2401 Frist Blvd, Fort Pierce, FL 34950
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    PSL Business Center: Prime Office Space
    $14 SF/Yr
    114,884 SF

    PSL Business Center: Prime Office Space

    St. Lucie West Office Suites, 192-33,300 SF

    580 University Blvd, Port St. Lucie, FL 34986
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    Port St. Lucie Flex Building
    $14 SF/Yr
    48,720 SF

    Port St. Lucie Flex Building

    Industrial flex building with air-conditioned office space for lease.

    651 NW Enterprise Dr, Port Saint Lucie, FL 34986
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    St. Lucie West Office Space
    $23 SF/Yr
    45,416 SF

    St. Lucie West Office Space

    Professional and Medical office space in landmark building for lease.

    1660 SW St. Lucie Blvd West, Port Saint Lucie, FL 34986
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    St. Lucie West Office Space
    $23 SF/Yr
    2,021 SF

    St. Lucie West Office Space

    Professional and medical office space in St. Lucie West.

    1660 SW St Lucie Blvd W, Port St Lucie, FL
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    St Lucie West Professional Offices
    $25 SF/Yr
    3,076 SF

    St Lucie West Professional Offices

    Medical and professional offices in the heart of St Lucie West.

    525 NW Lake Whitney Pl, Port Saint Lucie, FL 34986
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    Executive Office Suites For Rent
    $500 / Mo
    231 SF

    Executive Office Suites For Rent

    Executive office suites available for lease in Port St. Lucie.

    951 SW Country Clb Dr, Port St Lucie, FL
    View details

    St Lucie County, FL Office space Leasing Opportunities Market Analysis

    Explore Office space leasing options in St Lucie County, FL with 78 listings featured on our commercial real estate exchange. The current inventory includes 40,321,382,475 square feet of properties with an estimated lease value of $1,167 /Mo.

    Estimated lease rates for Office space in St Lucie County, FL begin at $3 SF/Yr, with an average of $21 SF/Yr and extend to $46 SF/Yr.
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    Browse Office space for Lease Near St Lucie, FL

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