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Sanford, FL Office Space for Lease

22 results
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Sanford Retail/Office/Medical Space For Lease
$25 SF/Yr
800 SF

Sanford Retail/Office/Medical Space For Lease

2422 S French Ave, Sanford, FL 32771

Prime commercial space suitable for retail, office, or medical use.

  • Prime commercial location with excellent visibility and frontage on South French Avenue.
  • Suitable for a variety of uses: retail, office, professional services, medical, or light commercial.
  • Convenient access for customers and employees with easy ingress and egress.
  • Centrally located near downtown Sanford, major roadways (US‑17/92, SR 46, I‑4), and surrounding developments.
  • Flexible floor plan options and ample natural light.
Updated: Jan 30
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Private Office in Sanford
$650 / Mo
117 SF

Private Office in Sanford

4031 W State Road 46, Sanford, FL 32771

Professional office space with shared amenities in a convenient location.

  • Private office space ideal for focused work and client meetings.
  • Convenient Sanford location near SR 46 / W 1st Street with easy access to major roads.
  • Shared access to restroom, kitchenette, reception area, and meeting room.
  • Well‑maintained office park environment.
  • Central heating and air conditioning.
Updated: Oct 20, 2025
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SANFORD, FL Office Space
$20 SF/Yr
2,000 SF

SANFORD, FL Office Space

2,000 SF professional office space for lease in SANFORD, FL.

690 Lake Forest Blvd, Sanford, FL 32771
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Sanford Commercial Office Building For Rent
$2,495 / Mo
2,641 SF

Sanford Commercial Office Building For Rent

Versatile commercial office building with reception area and large offices.

502 E Airport Blvd, Sanford, FL 32773
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Sanford Mixed-Use Space For Lease
$18 SF/Yr
90,008 SF

Sanford Mixed-Use Space For Lease

Multiple units available in a centrally located, professionally managed building.

500 W Lake Mary Blvd, Sanford, FL 32773
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Sanford Mixed-Use Space For Rent
$18 SF/Yr
90,008 SF

Sanford Mixed-Use Space For Rent

Multiple units available in a centrally located, professionally managed building.

500 W Lake Mary Blvd, Sanford, FL 32773
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Sanford Mixed-Use Space For Lease
$18 SF/Yr
90,008 SF

Sanford Mixed-Use Space For Lease

Multiple units available in centrally located Sanford mixed-use property.

500 W Lake Mary Blvd, Sanford, FL 32773
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Sanford Office Space For Lease
$18 SF/Yr
2,500 SF

Sanford Office Space For Lease

Office spaces ranging from 1,400 to 35,000 square feet available.

520 W Lake Mary Blvd, Sanford, FL 32773
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Sanford Mini Suites For Lease
$6,000 / Mo

Sanford Mini Suites For Lease

Semi-furnished office space near Sanford Airport, ideal for professional services.

602 W 27Th St, Sanford, FL 32773
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Renovated Office Space Available
$18 SF/Yr
1,975 SF

Renovated Office Space Available

Office space for lease in extensively renovated building.

1256-1280 Upsala Rd, Sanford, FL 32771
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Downtown Sanford Office Suites
Contact for pricing
12,078 SF

Downtown Sanford Office Suites

Flexible office suites in Sanford's historic district.

201 W 1St St, Sanford, FL 32771
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Downtown Sanford Historic Office Suites
$6,000 / Mo

Downtown Sanford Historic Office Suites

Charming office suites in walkable Downtown Sanford. Full service.

110 Suite A And B, Sanford, FL 32771
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Professional Office Space Available
$86,750

Professional Office Space Available

New construction office space near HCA regional hospital.

600 Lexington Green Ln, Sanford, FL 32771
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Sanford Historic District Office Space
$41,856

Sanford Historic District Office Space

Office spaces in Sanford's Historic District with ample parking.

110 W 1St St, Sanford, FL 32771
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Sanford Office Space For Rent
$43,000

Sanford Office Space For Rent

2,150 SF office space near Seminole Town Center.

245 Bellagio Cir, Sanford, FL 32771
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Sanford Flex Space Available Now
$48,000

Sanford Flex Space Available Now

Functional flex space with office and warehouse in Sanford's I-4 corridor.

260 Power Ct, Sanford, FL 32771
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Orlando Sanford Airport Flex Space
$12 SF/Yr
13,500 SF

Orlando Sanford Airport Flex Space

Flex/office/industrial space near Orlando Sanford International Airport.

2800-2848 South Mellonville Ave, Sanford, FL 32773
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Office Space at Towne Center
Contact for pricing

Office Space at Towne Center

Office space available for rent at 200 Towne Center.

Sanford, FL 32771
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Office Space on Rinehart Road
Contact for pricing
5,200 SF

Office Space on Rinehart Road

Office space with visibility and ample parking near major routes.

1381 Rinehart Rd, Sanford, FL 32771
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Sanford Retail Condo - 29,618 SF
$0.01 SF/Yr
29,618 SF

Sanford Retail Condo - 29,618 SF

Large Sanford retail space, ideal for diverse uses.

2921 Orlando Dr, Sanford, FL 32773
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Sanford Flex Space: 113 SF Office
$600 / Mo
113 SF

Sanford Flex Space: 113 SF Office

Prime Sanford location, 113 sq ft office, flexible lease.

1588 Tropic Park Dr, Sanford, FL 32773
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Sanford Flex Space for Lease
$50 SF/Yr
113 SF

Sanford Flex Space for Lease

113 sq ft office, immediate occupancy

1500 Tropic Park Dr, Sanford, FL 32773
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Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 22 Active listings in Sanford, FL, we suggest exploring alternatives. Similar 7 Properties for Sales.

Explore Similar Spaces for Sale in Sanford, FL

Consider Similar Space for Sale. We found 7 Spaces in Nearby Locations matching your search parameters.

Remodeled Historic Mixed-Use Building
$2,450,000
7,987 SF

Remodeled Historic Mixed-Use Building

Remodeled historic commercial building in Downtown Sanford's vibrant business district.

121 E 1St St, Sanford, FL 32771
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Prime Sanford Commercial/Mixed-Use Land
Pending
$349,900
0.76 Acres

Prime Sanford Commercial/Mixed-Use Land

Versatile commercial property near downtown Sanford with redevelopment potential.

420 Monroe Rd, Sanford, FL 32771
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Sanford, FL Office space Leasing Opportunities Market Analysis

Explore Office space leasing options in Sanford, FL with 29 listings featured on our commercial real estate exchange. The current inventory includes 12,792,265,200 square feet of properties with an estimated lease value of $275 SF/Yr.

Estimated lease rates for Office space in Sanford, FL begin at $11 SF/Yr, with an average of $25 SF/Yr and extend to $66 SF/Yr.
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