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    Sussex County, DE Office Space for Lease

    38 results
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    Professional Office Space For Lease
    $23 SF/Yr
    46,609 SF

    Professional Office Space For Lease

    16529 N Coastal Hwy, Lewes, DE 19958

    Versatile office space ideal for medical or executive use.

    • Prime professional space ideal for medical, executive, or professional office use.
    • Versatile layout featuring multiple private offices/exam rooms, reception area, and flexible workspaces.
    • Excellent front‑facing visibility and convenient client access.
    • Strategically positioned near major healthcare destinations.
    • Opportunity to customize the layout based on operational needs.
    Updated: Jan 2
    View details
    Versatile Professional Space in Lewes
    $23 SF/Yr
    46,609 SF

    Versatile Professional Space in Lewes

    16529 N Coastal Hwy, Lewes, DE 19958

    Prime medical or executive office space for lease in Lewes.

    • Prime professional space suitable for medical or executive office use.
    • Excellent front‑facing visibility and convenient client access.
    • Versatile layout with 3 private offices/exam rooms, reception area, shared lobby, and flexible workspaces.
    • Strategically located near major healthcare destinations.
    • Opportunity to customize the layout based on operational needs.
    Updated: Jan 2
    View details
    Versatile Professional Space in Lewes
    $23 SF/Yr
    46,609 SF

    Versatile Professional Space in Lewes

    Prime medical or executive office space with customizable layout.

    16529 N Coastal Hwy, Lewes, DE 19958
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    Prime Milford Office Space Available
    $1,110 / Mo

    Prime Milford Office Space Available

    Highly visible office space in the heart of Milford.

    23 NW Front St, Milford, DE 19963
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    Milford Commercial Space For Lease
    $750 / Mo
    37,462 SF

    Milford Commercial Space For Lease

    Commercial space available for lease in Milford, Delaware.

    908 N Church Ave, Milford, DE 19963
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    Seaford Office Suites For Rent
    $1,000 / Mo
    43,560 SF

    Seaford Office Suites For Rent

    Office suites with shared amenities, utilities, and internet included.

    957 Norman Eskridge Hwy, Seaford, DE 19973
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    Spacious Commercial Space in Lewes
    $4,000 / Mo
    21,344 SF

    Spacious Commercial Space in Lewes

    Large commercial space with parking and flexible usage options available.

    17569 Nassau Cmns Blvd, Lewes, DE 19958
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    Downtown Seaford Commercial Units Available
    $595 / Mo

    Downtown Seaford Commercial Units Available

    Newly renovated commercial units in downtown Seaford, Delaware.

    221 High St, Seaford, DE 19973
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    Lewes Office/Flex Space Available
    $22 SF/Yr

    Lewes Office/Flex Space Available

    Professional office/flex space in Lewes, DE, ideal for various businesses.

    32191 Nassau Rd, Lewes, DE 19958
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    Seaford, DE Medical Office Space
    $1,500 / Mo
    24,829 SF

    Seaford, DE Medical Office Space

    Move-in ready office space near Tidal Health Nanticoke hospital.

    808 Middleford Rd, Seaford, DE 19973
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    Seaford, DE Commercial Space
    $1,800 / Mo

    Seaford, DE Commercial Space

    Move-in ready commercial space near Tidal Health Nanticoke hospital.

    808 Middleford Rd, Seaford, DE 19973
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    Seaford, DE Commercial Condo Suite
    $12 SF/Yr

    Seaford, DE Commercial Condo Suite

    Commercial condo suite in Seaford with multiple exam and private offices.

    543 N Shipley St, Seaford, DE 19973
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    Seaford, DE Commercial Space For Lease
    $1,500 / Mo
    24,829 SF

    Seaford, DE Commercial Space For Lease

    Move-in ready commercial space ideal for medical or healthcare businesses.

    808 Middleford Rd, Seaford, DE 19973
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    Georgetown Office Space For Lease
    $820 / Mo
    6,970 SF

    Georgetown Office Space For Lease

    First floor office space with shared amenities in Georgetown, DE.

    4 E Laurel St, Georgetown, DE 19947
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    Versatile Commercial Space in Selbyville
    $1,600 / Mo

    Versatile Commercial Space in Selbyville

    Adaptable space for medical, retail, or office use in Selbyville.

    38555 Dupont Blvd, Selbyville, DE 19975
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    Seaford Office Space For Rent
    $950 / Mo

    Seaford Office Space For Rent

    800 sq ft office space available January 1, 2026.

    312 E Stein Hwy, Seaford, DE 19973
    View details
    New Retail/Office Building on Route
    $30 SF/Yr
    3,000 SF

    New Retail/Office Building on Route

    Two-story retail and office building along Route 113.

    155 Dupont Blvd, Georgetown, DE 19947
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    Route 1 Commercial Space Available
    $3,000 / Mo

    Route 1 Commercial Space Available

    Prime commercial space on Route 1, available immediately.

    18354 Coastal Hwy, Lewes, DE 19958
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    Commercial Space on Mulberry Street
    $14 SF/Yr

    Commercial Space on Mulberry Street

    1,200 SF commercial space suitable for office, retail, or medical.

    622 Mulberry St, Milton, DE 19968
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    Office Space Near Hiking Trail
    $795 / Mo

    Office Space Near Hiking Trail

    Office space available near Route 1 and hiking trail.

    19878 Hebron Rd, Rehoboth Beach, DE 19971
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    Turn-Key Ready Office/Retail Space
    $2,500 / Mo
    1,500 SF

    Turn-Key Ready Office/Retail Space

    Prime location on Route 13, Delmar, DE. High visibility.

    31010 Thornton Blvd, Delmar, DE
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    Medical/Office Space Available for Rent
    $24 SF/Yr
    1,350 SF

    Medical/Office Space Available for Rent

    1350 SF medical/office space available for rent.

    100 Silicato Pkwy, Milford, DE 19963
    View details
    Ocean View Retail/Office Space
    $22 SF/Yr

    Ocean View Retail/Office Space

    Flexible 2,200 SF space in high-traffic plaza.

    29 Atlantic Ave, Ocean View, DE 19970
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    Office Space in Nassau Commons
    $1,500 / Mo

    Office Space in Nassau Commons

    Office space available for lease starting October 1, 2025.

    17577 Nassau Commons Blvd, Lewes, DE 19958
    View details

    Sussex County, DE Office space Leasing Opportunities Market Analysis

    Explore Office space leasing options in Sussex County, DE with 49 listings featured on our commercial real estate exchange. The current inventory includes 13,001,379,170 square feet of properties with an estimated lease value of $5,796 /Mo.

    Estimated lease rates for Office space in Sussex County, DE begin at $1.48 SF/Yr, with an average of $386 /Mo and extend to $1,800 /Mo.
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    Browse Office space for Lease Near Sussex, DE

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