For Lease
  • For Sale
  • For Lease
  • Recently Sold
  • Property Lookup
  • Brokers
Space Uses
  • Retail
  • Restaurant
  • Office
  • Coworking
  • Medical Space
  • Automotive
  • Industrial
  • Warehouse
  • Flex
  • Hospitality
  • Sports & Entertainment
  • Specialty
Price
Price range
$
$
Size
Property size / sq.ft.

Lewes, DE Office Units for Lease

List
Map
6 results
Versatile Lewes Office Space
$23 SF/Yr

Versatile Lewes Office Space

16529 N COASTAL Highway, Lewes, DE 19958

Professional office space ideal for medical or executive use.

  • Versatile layout ideal for medical, executive, or professional office use, featuring multiple private offices/exam rooms and flexible workspaces.
  • Excellent front‑facing visibility and convenient client access.
  • Strategically positioned near major healthcare destinations.
  • Opportunity to customize the layout based on operational needs.
  • Two potential reception areas at the main front entrance and a large lobby.
Updated: Feb 23
View details
Lewes Office Space For Lease
$6,000 /Mo

Lewes Office Space For Lease

17503 NASSAU COMMONS Boulevard, Lewes, DE 19958

3,200 SF office space in desirable Nassau Commons.

  • Located in the highly desirable Nassau Commons commercial corridor near Coastal Highway and Lewes‑Georgetown Highway.
  • 3,200‑square‑foot building suitable for a variety of commercial uses.
  • Features a reception area, kitchen, five offices, storage area, two bathrooms, and mechanical room.
  • Adjacent to Redner's grocery store and the bike trail.
  • Exterior features include landscaping, covered porch, and patio.
Updated: Apr 17
View details
Lewes Office/Flex Space Available
$20 SF/Yr

Lewes Office/Flex Space Available

Professional office/flex space in Lewes, DE, ideal for various uses.

32191 NASSAU Road, Lewes, DE 19958
View details
Single-Room Office Suite in Lewes
$575 /Mo

Single-Room Office Suite in Lewes

Second-floor office suite with shared amenities, utilities included.

17527 NASSAU COMMONS Boulevard, Lewes, DE 19958
View details
New Retail/Office Pad Sites
$30 SF/Yr

New Retail/Office Pad Sites

Two new construction pad sites in a vibrant community.

Zinfandel Lane, Lewes, DE 19958
View details
Coastal Highway Commercial Opportunity
Contact for pricing

Coastal Highway Commercial Opportunity

Prime commercial parcel on Coastal Highway, available February 2026.

18355 Coastal Hwy, Lewes, DE 19958
View details
Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 6 Active listings in Lewes, DE, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

Explore Office Units for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Versatile Retail/Office/Flex Space Available
$12 SF/Yr
2,925 SF

Versatile Retail/Office/Flex Space Available

2,925 sqft retail/office/flex space in Laurel, DE for lease.

10771 LAUREL PLAZA ROAD, Laurel, DE 19956
View details
CommercialLease - LAUREL, DE
$2,680 /Mo

CommercialLease - LAUREL, DE

Flex space

10771 LAUREL PLAZA ROAD, Laurel, DE 19956
View details
Downtown Milford Small Business Suites
$595 /Mo

Downtown Milford Small Business Suites

Suites available in Milford's Small Business Incubation Center.

18 SW SOUTHWEST FRONT STREET, Milford, DE 19963
View details
Medical/Office Space Available for Rent
$24 SF/Yr
1,350 SF

Medical/Office Space Available for Rent

1350 SF medical/office space available for rent.

100 Silicato Pkwy, Milford, DE
View details

Explore Similar Spaces for Sale in Lewes, DE

Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

Versatile Commercial Space For Sale
Contact for pricing
1,962 SF

Versatile Commercial Space For Sale

Adaptable 1,962 SF commercial space, ideal for various businesses.

32191 Nassau Road, Lewes, DE 19958
View details
Office/Flex Space For Sale
Contact for pricing

Office/Flex Space For Sale

Professional office/flex space ideal for design, consulting, or fitness.

32191 Nassau Road 2, Lewes, DE 19958
View details

Lewes, DE Office Units Leasing Opportunities Market Analysis

Explore Office Units leasing options in Lewes, DE with 6 listings featured on our commercial real estate exchange. The current inventory includes 2,030,296,718 square feet of properties with an estimated lease value of $23 SF/Yr.

Estimated lease rates for Office Units in Lewes, DE begin at $23 SF/Yr, with an average of $23 SF/Yr and extend to $23 SF/Yr.
List
Map