Palmdale, CA Office Units for Rent & Lease

Updated: Aug 15, 2025

Front-Facing Desk Space in Shopping Center

533 E Palmdale Boulevard, Palmdale, CA 93550

$550/Mo

1,100 sqft

Desk space for rent in a well‑established shopping center in Palmdale
Storefront on Palmdale Blvd
Building constructed with concrete
Central heating and central air conditioning with natural gas
Asphalt roof

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Updated: Sep 29, 2025

Desk in Shared Office Suite

533 E Palmdale Boulevard, Palmdale, CA 93550

$450/Mo

1,000 sqft

Shopping center on Palmdale Blvd
Office desk for rent inside includes space for two clients, one chair, and a metal filing cabinet
Includes internet service
Desk can be used for DMV, insurance, or loans

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Move-In Ready Palmdale Office Space

4621 S Avenue, Palmdale, CA 93552

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2,072 sqft

Multiple suites available in Palmdale, CA, ready for occupancy.

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Remodeled Retail/Office Suites

2140 E Palmdale Blvd, Palmdale, CA 93550

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7,000 sqft

Recently remodeled retail/office suites in an established shopping center with storefront glass and rear delivery doors.

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Palmdale Office Suite For Rent

38700 W 5th Street, Palmdale, CA 93551

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1,400 sqft

Move-in ready office suite in Palmdale Business Park.

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Palmdale Office Space Available

38660 Medical Center Dr., Palmdale, CA 93551

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59,577 sqft

Office suites available for lease in Palmdale, California.

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Move-in Ready Office Suite

38700 W 5th Street E, Palmdale, CA 93551

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1,400 sqft

Professional office suite for rent in Palmdale Business Park.

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Mixed-Use Retail and Office Center

4621 E Avenue S, Palmdale, CA 93552

$12 SF/Yr

New retail space on the ground floor with office and medical suites on the second level.

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Based on your search, we've compiled 24 Potential Opportunities for your consideration. Besides 8 Active listings in Palmdale, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 12 Properties for Sales.

Office Units for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

New Warehouse/Office Plaza in Lancaster

1133 W Ave L12, Lancaster, CA 93534

Contact for pricing

5,680 sqft

New construction warehouse and office spaces available for lease.

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Lancaster Office/Flex Space Available

42913 Capital Drive, Lancaster, CA 93535

Contact for pricing

3,298 sqft

Move-in ready office with roll-up door in Lancaster Business Park.

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Canyon Country Flex Space Available

18345 Sierra Hwy, Santa Clarita, CA

Contact for pricing

1,450 sqft

Flex, office, storage, and retail spaces available for lease.

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Santa Clarita Office Space Available

27651 Lincoln Place, Santa Clarita, CA 91387

Contact for pricing

30,732 sqft

Three-story office building in Santa Clarita with modern amenities.

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Similar Spaces for Sale in Palmdale, CA

Consider Similar Space for Sale. We found 12 Spaces matching your search parameters.

Four-Unit Mixed-Use Retail and Office

38262-68 E 6th Street, Palmdale, CA 93550

$567,000

3,228 sqft 0.16 AC lot

Four separately metered units offer individual heating and cooling, with two vacant and two month-to-month occupied.

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Palmdale Mixed-Use Investment Opportunity

38262 6th E, Palmdale, CA 93550

$562,000

3,228 sqft 0.16 AC lot

Mixed-use property with income potential in a prime location.

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Mixed-Use Building with Four Units

38262 6th, Palmdale, CA 93550

$567,000

3,228 sqft 0.16 AC lot

Four individually metered units offer a mix of vacant and month-to-month occupancy with separate climate systems.

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Office/Warehouse Condo in Palmdale

650 Commerce Avenue, Unit D, Palmdale, CA 93551

$435,000

2,427 sqft 5.29 AC lot

2,430 SF office/warehouse condo in excellent condition, built in 2007.

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Live-Work Office-Flex Property

38960 E 12th Street East ST E, Palmdale, CA 93550

$595,000

4.86 AC lot

Live-work office-flex setup on a fully fenced parcel with a one-bedroom home, shop with power, and RV hook-ups.

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Multi-Story Office Buildings

1309 E Palmdale Boulevard, Palmdale, CA 93550

$1,449,900

13,100 sqft 0.88 AC lot

Three office buildings on one lot with 18 individual offices, including one two-story structure and leased units.

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Remodeled Retail/Office Suite

2140 E Palmdale Boulevard Unit L, Palmdale, CA 93550

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5,269 sqft

Recently remodeled turn-key retail and office suite with floor-to-ceiling storefront glass and covered pedestrian entry.

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Mixed-Use Business Park Suites

833-861 Auto Center Dr., Palmdale, CA 93551

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37,735 sqft

Recently developed Craftsman-style park offers office, medical, and retail suites with ample parking and signage.

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Remodeled Retail/Office Suite

2140 E Palmdale Boulevard Unit M, Palmdale, CA 93550

Contact for pricing

1,731 sqft

Recently remodeled suite with floor-to-ceiling glass storefronts, ADA restrooms and a kitchenette, within an established shopping center.

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For-Sale Office Space

514 Commerce Ave., Palmdale, CA 93551

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2,588 sqft

For-sale office space totaling 2,588 SF at 514 Commerce Ave., Palmdale, CA.

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Renovated Retail/Office Property

1056 W Avenue N, Palmdale, CA 93551

Contact for pricing

1,664 sqft 2.20 AC lot

Renovated structure totaling 1,664 sq. ft. across two lots near a major freeway exit.

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Office Desk Suite in Shopping Center

533 E Palmdale Boulevard Unit A-2, Palmdale, CA 93550

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Desk suite available with client chairs, a filing cabinet, and internet service in a shopping center setting.

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