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    Palmdale, CA Medical Office Space for Sale

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    Los Angeles, CA Lancaster, CA San Diego, CA
    Medical Office Investment Opportunity
    $3,950,000
    13,200 SF

    Medical Office Investment Opportunity

    450 W Palmdale, Palmdale, CA 93551

    Two buildings near Palmdale Regional Medical Center for sale.

    • Priced at $156 per square foot.
    • Building 460 (13,200 sq ft) is available for owner‑user.
    • Building 450 generates approximately $280,000 in base rent and CAMs.
    • Qualifies for SBA financing due to 59% vacancy.
    • Ground lease through 2061.
    Updated: Apr 24
    View details
    Palmdale Freestanding Commercial Building
    $989,000
    3,500 SF

    Palmdale Freestanding Commercial Building

    38423 9th St E, Palmdale, CA 93550

    Well-maintained commercial building in Palmdale, ideal for owner-users or investors.

    • New Roof and HVAC (2024): Significant capital improvements reduce near‑term maintenance costs.
    • Lease‑Back Option: Immediate income stream of $5,000/month + NNN possible with flexible terms.
    • Below Replacement Cost: Offered at approximately $250/SF, a compelling value compared to market comps.
    • Freestanding Building: Rare opportunity in Palmdale.
    • High Cap Rate: Strong 6.86% cap rate based on proposed lease‑back scenario.
    Updated: Feb 4
    View details
    New Class A Medical Office
    Contact for pricing
    24,600 SF

    New Class A Medical Office

    New 24,600 SF Class A medical office building.

    42155 11th Street West, Palmdale, CA 93551
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    Palmdale DaVita For Sale
    $6,442,755
    13,750 SF

    Palmdale DaVita For Sale

    DaVita with long-term lease in Palmdale, California.

    38454 5th St W, Palmdale, CA 93551
    View details
    Based on your search, we've compiled 32 Potential Opportunities for your consideration. Besides 4 Active listings in Palmdale, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 20 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Medical Office Suite For Lease
    $2,075,000
    2,749 SF

    Medical Office Suite For Lease

    Ground floor corner suite with high-end finishes, available for lease.

    25425 Orchard Village Rd, Valencia, CA
    View details
    Medical Office Condo Near Hospital
    $450,000
    1,345 SF

    Medical Office Condo Near Hospital

    Medical office condo within Antelope Valley Hospital campus parking lot.

    44215 15th Street West , 307, Lancaster, CA 93534
    View details
    Freestanding Buildings on Hard Corner
    Contact for pricing
    300,000 SF

    Freestanding Buildings on Hard Corner

    Freestanding buildings ideal for restaurant, medical, office, or retail.

    43901-43997 15th Street West, Lancaster, CA 93534
    View details
    Valencia Retail/Restaurant Space For Sale
    Contact for pricing
    9,000 SF

    Valencia Retail/Restaurant Space For Sale

    Retail and restaurant spaces available in Valencia, California.

    SEC Newhall Ranch Rd. & Copper Hill Dr., Valencia, CA 91355
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Beverly Hills Adjacent Vacant Land
    $3,475,000
    0.17 Acres

    Beverly Hills Adjacent Vacant Land

    Vacant land suitable for medical, office, and other uses.

    1044 S Robertson Blvd, Los Angeles, CA 90035
    View details
    Prime Commercial Parcel Near Amazon
    $595,000
    425,580.00 Acres

    Prime Commercial Parcel Near Amazon

    9.77-acre commercial parcel near Amazon Distribution Center.

    0 Bear Valley Road, Victorville, CA 92392
    View details
    78.7 Acres in Apple Valley
    $3,500,000
    3,428,172.00 Acres

    78.7 Acres in Apple Valley

    Large acreage with commercial zoning and development potential in Apple Valley.

    0 Apple Valley Road, Apple Valley, CA 92308
    View details
    Prime Apple Valley Commercial Land
    $2,500,000
    823,284.00 Acres

    Prime Apple Valley Commercial Land

    18.9 acres of commercial land in a desirable location.

    1 Apple Valley Road, Apple Valley, CA 92308
    View details

    Explore Off-Market Properties in Palmdale, CA

    Consider similar Off-Market properties in Palmdale, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    300 Palmdale Blvd

    300 Palmdale Blvd

    MEDICAL BUILDING • 3,344 SF
    Value Estimation by Request
    300 Palmdale Blvd, Palmdale, CA 93550-4517
    View details
    2205 Palmdale Blvd

    2205 Palmdale Blvd

    MEDICAL BUILDING • 8,164 SF
    Value Estimation
    $1,580,000
    2205 Palmdale Blvd, Palmdale, CA 93550-1316
    View details
    1220 Ave S Ave

    1220 Ave S Ave

    MEDICAL BUILDING • 24,800 SF
    Value Estimation
    $3,560,000
    1220 Ave S Ave, Palmdale, CA 93550-6196
    View details
    38921 Trade Ctr Dr

    38921 Trade Ctr Dr

    MEDICAL BUILDING • 34,613 SF
    Value Estimation
    $7,805,000
    38921 Trade Ctr Dr, Palmdale, CA 93551-3652
    View details
    939 Palmdale Blvd

    939 Palmdale Blvd

    MEDICAL BUILDING • 1,813 SF
    Value Estimation by Request
    939 Palmdale Blvd, Palmdale, CA 93550-4711
    View details
    868 Auto Ctr Dr

    868 Auto Ctr Dr

    MEDICAL BUILDING • 13,718 SF
    Value Estimation
    $3,405,000
    868 Auto Ctr Dr, Palmdale, CA 93551-4690
    View details
    2508 Palmdale Blvd

    2508 Palmdale Blvd

    MEDICAL BUILDING • 6,158 SF
    Value Estimation
    $1,660,000
    2508 Palmdale Blvd, Palmdale, CA 93550-4860
    View details
    2710 Palmdale Blvd

    2710 Palmdale Blvd

    MEDICAL BUILDING • 7,308 SF
    Value Estimation
    $1,635,000
    2710 Palmdale Blvd, Palmdale, CA 93550-4946
    View details
    1051 Ave M14

    1051 Ave M14

    MEDICAL BUILDING • 6,219 SF
    Value Estimation
    $1,195,000
    1051 Ave M14, Palmdale, CA 93551-1434
    View details
    510 Rancho Vis Blvd

    510 Rancho Vis Blvd

    MEDICAL BUILDING • 4,070 SF
    Value Estimation
    $825,000
    510 Rancho Vis Blvd, Palmdale, CA 93551-3737
    View details
    1021 Ave M14

    1021 Ave M14

    MEDICAL BUILDING • 6,045 SF
    Value Estimation
    $1,200,000
    1021 Ave M14, Palmdale, CA 93551-1440
    View details
    Palmdale CA Ave. Q And Trade Ctr Dr

    Palmdale CA Ave. Q And Trade Ctr Dr

    Medical Office Space
    Value Estimation by Request
    Palmdale CA Ave. Q And Trade Ctr Dr, Palmdale, CA 93551
    View details
    2231 Palmdale Blvd

    2231 Palmdale Blvd

    Medical Office Space • 34,319 SF
    Value Estimation by Request
    2231 Palmdale Blvd, Palmdale, CA 93550
    View details
    Avenue O

    Avenue O

    Medical Office Space • 4.04 Acres
    Value Estimation by Request
    0 Avenue O, Palmdale, CA 93551
    View details
    635 Commerce Ave

    635 Commerce Ave

    Medical Office Space • 5,000 SF
    Value Estimation by Request
    635 Commerce Ave, Palmdale, CA 93551
    View details
    10Th St

    10Th St

    Neighborhood centers
    Value Estimation by Request
    0 10Th St, Palmdale, CA 93551
    View details
    921 Palmdale Blvd

    921 Palmdale Blvd

    Medical Office Space • 5,518 SF
    Value Estimation by Request
    921 Palmdale Blvd, Palmdale, CA 93550
    View details
    833 Auto Ctr Dr

    833 Auto Ctr Dr

    MEDICAL BUILDING • 6,550 SF
    Value Estimation
    $1,475,000
    833 Auto Ctr Dr, Palmdale, CA 93551-4488
    View details
    847 Auto Ctr Dr

    847 Auto Ctr Dr

    MEDICAL BUILDING • 3,820 SF
    Value Estimation
    $870,000
    847 Auto Ctr Dr, Palmdale, CA 93551-4490
    View details
    843 Auto Ctr Dr

    843 Auto Ctr Dr

    MEDICAL BUILDING • 8,470 SF
    Value Estimation
    $1,860,000
    843 Auto Ctr Dr, Palmdale, CA 93551-4489
    View details

    Palmdale, CA Medical Office Space Investment Opportunities Market Analysis

    Explore 24 medical office space for sale in Palmdale, CA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 30,450 square feet of properties for sale, with an estimated market value of $11,381,755.

    Sale prices for medical spaces in Palmdale, CA start at $989,000, averaging $3,793,918, and reaching up to $6,442,755 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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