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    Palmdale, CA Medical Office Space for Sale

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    Lancaster, CA Acton, CA Littlerock, CA
    Medical Office Investment Opportunity
    $3,950,000
    13,200 SF
    Medical Office Investment Opportunity

    450 W Palmdale, Palmdale, CA 93551

    Two buildings near Palmdale Regional Medical Center for sale.
    • Priced at $156 per square foot.
    • Building 460 (13,200 sq ft) is available for owner‑user.
    • Building 450 generates approximately $280,000 in base rent and CAMs.
    • Qualifies for SBA financing due to 59% vacancy.
    • Ground lease through 2061.
    Updated: Apr 24
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    Palmdale Freestanding Commercial Building
    $989,000
    3,500 SF
    Palmdale Freestanding Commercial Building

    38423 9th St E, Palmdale, CA 93550

    Well-maintained commercial building in Palmdale, ideal for owner-users or investors.
    • New Roof and HVAC (2024): Significant capital improvements reduce near‑term maintenance costs.
    • Lease‑Back Option: Immediate income stream of $5,000/month + NNN possible with flexible terms.
    • Below Replacement Cost: Offered at approximately $250/SF, a compelling value compared to market comps.
    • Freestanding Building: Rare opportunity in Palmdale.
    • High Cap Rate: Strong 6.86% cap rate based on proposed lease‑back scenario.
    Updated: Feb 4
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    Palmdale DaVita For Sale
    $6,442,755
    13,750 SF
    Palmdale DaVita For Sale

    DaVita with long-term lease in Palmdale, California.

    38454 5th St W, Palmdale, CA 93551

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    New Class A Medical Office
    Contact for pricing
    24,600 SF
    New Class A Medical Office

    New 24,600 SF Class A medical office building.

    42155 11th Street West, Palmdale, CA 93551

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    Based on your search, we've compiled 32 Potential Opportunities for your consideration. Besides 4 Active listings in Palmdale, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 20 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Medical Office Suite For Lease
    $2,075,000
    2,749 SF
    Medical Office Suite For Lease

    Ground floor corner suite with high-end finishes, available for lease.

    25425 Orchard Village Rd, Valencia, CA

    View details
    Freestanding Retail/Medical Building
    Contact for pricing
    7,112 SF
    Freestanding Retail/Medical Building

    Hard-corner building with flexible configurations and strong visibility near a major hospital and abundant parking.

    43901-43997 15th Street West, Lancaster, CA 93534

    View details
    Medical Office Condo Near Hospital
    $450,000
    1,345 SF
    Medical Office Condo Near Hospital

    Medical office condo within Antelope Valley Hospital campus parking lot.

    44215 15th Street West , 307, Lancaster, CA 93534

    View details
    Valencia Retail/Restaurant Space For Sale
    Contact for pricing
    9,000 SF
    Valencia Retail/Restaurant Space For Sale

    Retail and restaurant spaces available in Valencia, California.

    SEC Newhall Ranch Rd. & Copper Hill Dr., Valencia, CA 91355

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Beverly Hills Adjacent Vacant Land
    $3,475,000
    0.17 Acres
    Beverly Hills Adjacent Vacant Land

    Vacant land suitable for medical, office, and other uses.

    1044 S Robertson Blvd, Los Angeles, CA 90035

    View details
    Prime Commercial Parcel Near Amazon
    $595,000
    425,580.00 Acres
    Prime Commercial Parcel Near Amazon

    9.77-acre commercial parcel near Amazon Distribution Center.

    0 Bear Valley Road, Victorville, CA 92392

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    78.7 Acres in Apple Valley
    $3,500,000
    3,428,172.00 Acres
    78.7 Acres in Apple Valley

    Large acreage with commercial zoning and development potential in Apple Valley.

    0 Apple Valley Road, Apple Valley, CA 92308

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    Prime Apple Valley Commercial Land
    $2,500,000
    823,284.00 Acres
    Prime Apple Valley Commercial Land

    18.9 acres of commercial land in a desirable location.

    1 Apple Valley Road, Apple Valley, CA 92308

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    Off-Market Properties in Palmdale, CA

    Consider similar Off-Market properties in Palmdale, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    300 Palmdale Blvd
    MEDICAL BUILDING
    3,344 SF Lot: 0.24 Acres
    Value Estimation by Request

    300 Palmdale Blvd, Palmdale, CA 93550-4517

    View details
    2205 Palmdale Blvd
    MEDICAL BUILDING
    8,164 SF Lot: 0.56 Acres
    Estimated value
    $1,580,000

    2205 Palmdale Blvd, Palmdale, CA 93550-1316

    View details
    1220 Ave S Ave
    MEDICAL BUILDING
    24,800 SF Lot: 2.15 Acres
    Estimated value
    $3,560,000

    1220 Ave S Ave, Palmdale, CA 93550-6196

    View details
    38921 Trade Ctr Dr
    MEDICAL BUILDING
    34,613 SF Lot: 2.27 Acres
    Estimated value
    $7,805,000

    38921 Trade Ctr Dr, Palmdale, CA 93551-3652

    View details
    939 Palmdale Blvd
    MEDICAL BUILDING
    1,813 SF Lot: 0.14 Acres
    Value Estimation by Request

    939 Palmdale Blvd, Palmdale, CA 93550-4711

    View details
    868 Auto Ctr Dr
    MEDICAL BUILDING
    13,718 SF Lot: 1.69 Acres
    Estimated value
    $3,405,000

    868 Auto Ctr Dr, Palmdale, CA 93551-4690

    View details
    2508 Palmdale Blvd
    MEDICAL BUILDING
    6,158 SF Lot: 0.59 Acres
    Estimated value
    $1,660,000

    2508 Palmdale Blvd, Palmdale, CA 93550-4860

    View details
    2710 Palmdale Blvd
    MEDICAL BUILDING
    7,308 SF Lot: 0.66 Acres
    Estimated value
    $1,635,000

    2710 Palmdale Blvd, Palmdale, CA 93550-4946

    View details
    1051 Ave M14
    MEDICAL BUILDING
    6,219 SF Lot: 0.43 Acres
    Estimated value
    $1,195,000

    1051 Ave M14, Palmdale, CA 93551-1434

    View details
    510 Rancho Vis Blvd
    MEDICAL BUILDING
    4,070 SF Lot: 0.47 Acres
    Estimated value
    $825,000

    510 Rancho Vis Blvd, Palmdale, CA 93551-3737

    View details
    1021 Ave M14
    MEDICAL BUILDING
    6,045 SF Lot: 0.57 Acres
    Estimated value
    $1,200,000

    1021 Ave M14, Palmdale, CA 93551-1440

    View details
    Palmdale CA Ave. Q And Trade Ctr Dr
    Medical Office Space
    Value Estimation by Request

    Palmdale CA Ave. Q And Trade Ctr Dr, Palmdale, CA 93551

    View details
    2231 Palmdale Blvd
    Medical Office Space
    34,319 SF
    Value Estimation by Request

    2231 Palmdale Blvd, Palmdale, CA 93550

    View details
    Avenue O
    Medical Office Space
    Lot: 4.04 Acres
    Value Estimation by Request
    Avenue O

    0 Avenue O, Palmdale, CA 93551

    View details
    635 Commerce Ave
    Medical Office Space
    5,000 SF Lot: 1.00 Acre

    635 Commerce Ave, Palmdale, CA 93551

    View details
    10Th St
    Neighborhood centers
    Value Estimation by Request
    10Th St

    0 10Th St, Palmdale, CA 93551

    View details
    921 Palmdale Blvd
    Medical Office Space
    5,518 SF
    Value Estimation by Request

    921 Palmdale Blvd, Palmdale, CA 93550

    View details
    833 Auto Ctr Dr
    MEDICAL BUILDING
    6,550 SF Lot: 5.56 Acres
    Estimated value
    $1,475,000

    833 Auto Ctr Dr, Palmdale, CA 93551-4488

    View details
    847 Auto Ctr Dr
    MEDICAL BUILDING
    3,820 SF Lot: 5.56 Acres
    Estimated value
    $870,000

    847 Auto Ctr Dr, Palmdale, CA 93551-4490

    View details
    843 Auto Ctr Dr
    MEDICAL BUILDING
    8,470 SF Lot: 5.56 Acres
    Estimated value
    $1,860,000

    843 Auto Ctr Dr, Palmdale, CA 93551-4489

    View details

    Palmdale, CA Medical Office Space Investment Opportunities Market Analysis

    Explore 24 medical office space for sale in Palmdale, CA, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 30,450 square feet of properties for sale, with an estimated market value of $11,381,755.

    Sale prices for medical spaces in Palmdale, CA start at $989,000, averaging $3,793,918, and reaching up to $6,442,755 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

    List
    Map

    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 13
    Medical Office Space 7
    Office buildings 7
    Coworking space 3

    Demographics Overview

    Population 186K
    Population Growth (5Y) +8.7%
    Median Household Income $82,536
    College Educated 13.7%

    High-Yield Neighborhoods for Investment

    Identify Palmdale submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    93550 $989K
    93551 $5.2M

    Taxes & Financing

    Tax Rate (average for all types) 1.59%
    Property Tax per SF $32.01 per SF
    Tax Rate vs County Average 0.33 pp above county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Los Angeles County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Los Angeles County

    Retail

    Office

    Residential Income

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