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    Palmdale, CA
    Medical Premises

    Palmdale, CA Medical Office Space for Sale

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    Medical Office Investment Opportunity
    Updated: Dec 3, 2025
    Medical Office Investment Opportunity

    450 W Palmdale, Palmdale, CA 93551

    $3,950,000
    13,200 sqft
    Priced at $156 per square foot.
    Building 460 (13,200 sq ft) is available for owner‑user.
    Building 450 generates approximately $280,000 in base rent and CAMs.
    Qualifies for SBA financing due to 59% vacancy.
    Ground lease through 2061.
    View details
    Palmdale DaVita For Sale
    Updated: Oct 15, 2025
    Palmdale DaVita For Sale

    38454 5th St W, Palmdale, CA 93551

    Contact for pricing
    13,750 sqft 1.46 AC lot
    Long‑term lease with DaVita, extending over 10 years.
    Strong credit tenant: DaVita Inc. (DVA), a publicly traded company with an $8.86 Billion market cap.
    High‑traffic location:** Situated on 5th St W, near the 14 Freeway, with a combined 140,000 vehicles per day.
    Ideal demographics: 130,000 people and $80,000 household income within a 5‑mile radius.
    Proximity to Palmdale Medical Center (less than a mile away).
    View details
    New Construction Office Building
    New Construction Office Building

    41255 11th Street West, Palmdale, CA 93551

    Contact for pricing

    Brand-new office property with adaptable interiors, dedicated parking, and PDM4 zoning for medical or professional office use.

    View details
    See what stands out in Los Angeles County

    We check every for-sale listing in the county against comparable properties across the country. Most price about where you would expect. A few are worth a second look.

    We check every listing here. A few are worth a second look.

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    Based on your search, we've compiled 27 Potential Opportunities for your consideration. Besides 3 Active listings in Palmdale, CA, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 20 Off-Market properties to explore as potential leads

    Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Remodeled Medical Office Building
    Remodeled Medical Office Building

    7341 Foothill Boulevard, Tujunga, CA 91042

    $2,449,944
    6,139 sqft 0.22 AC lot

    Four updated units provide flexible space for medical, professional, or mixed commercial occupancy.

    View details
    Medical Office Condominium with Clinical Buildout
    Medical Office Condominium with Clinical Buildout

    150-44725 10th St W, Lancaster, CA 93534

    $565,000
    1,971 sqft

    Purpose-built healthcare suite with patient, treatment, administrative, and support areas already configured for medical operations.

    View details
    Four-Unit Medical Office Building
    Four-Unit Medical Office Building

    7341 Foothill Boulevard, Tujunga, CA 91042

    $2,449,944

    Extensive remodeling and modern improvements support medical, professional, or mixed commercial use.

    View details
    Upper-Corner Medical Office Condo
    Upper-Corner Medical Office Condo

    290-44725 10th St W, Lancaster, CA 93534

    $295,000

    Medical suite with clinical rooms, administrative offices, restrooms, and included furnishings and equipment.

    View details

    Off-Market Properties in Palmdale, CA

    Consider similar Off-Market properties in Palmdale, CA. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    300 Palmdale Blvd
    MEDICAL BUILDING

    300 Palmdale Blvd, Palmdale, CA 93550-4517

    Estimated value:
    $240,000
    3,344 sqft 0.24 AC lot
    View details
    2205 Palmdale Blvd
    MEDICAL BUILDING

    2205 Palmdale Blvd, Palmdale, CA 93550-1316

    Estimated value:
    $1,605,000
    8,164 sqft 0.56 AC lot
    View details
    1220 Ave S Ave
    MEDICAL BUILDING

    1220 Ave S Ave, Palmdale, CA 93550-6196

    Estimated value:
    $3,560,000
    24,800 sqft 2.15 AC lot
    View details
    38921 Trade Ctr Dr
    MEDICAL BUILDING

    38921 Trade Ctr Dr, Palmdale, CA 93551-3652

    Estimated value:
    $7,805,000
    34,613 sqft 2.27 AC lot
    View details
    939 Palmdale Blvd
    MEDICAL BUILDING

    939 Palmdale Blvd, Palmdale, CA 93550-4711

    Estimated value:
    $300,000
    1,813 sqft 0.14 AC lot
    View details
    868 Auto Ctr Dr
    MEDICAL BUILDING

    868 Auto Ctr Dr, Palmdale, CA 93551-4690

    Estimated value:
    $3,405,000
    13,718 sqft 1.69 AC lot
    View details
    2508 Palmdale Blvd
    MEDICAL BUILDING

    2508 Palmdale Blvd, Palmdale, CA 93550-4860

    Estimated value:
    $1,660,000
    6,158 sqft 0.59 AC lot
    View details
    2710 Palmdale Blvd
    MEDICAL BUILDING

    2710 Palmdale Blvd, Palmdale, CA 93550-4946

    Estimated value:
    $1,635,000
    7,308 sqft 0.66 AC lot
    View details
    1051 Ave M14
    MEDICAL BUILDING

    1051 Ave M14, Palmdale, CA 93551-1434

    Estimated value:
    $1,195,000
    6,219 sqft 0.43 AC lot
    View details
    510 Rancho Vis Blvd
    MEDICAL BUILDING

    510 Rancho Vis Blvd, Palmdale, CA 93551-3737

    Estimated value:
    $825,000
    4,070 sqft 0.47 AC lot
    View details
    1021 Ave M14
    MEDICAL BUILDING

    1021 Ave M14, Palmdale, CA 93551-1440

    Estimated value:
    $1,200,000
    6,045 sqft 0.57 AC lot
    View details
    Palmdale CA Ave. Q And Trade Ctr Dr
    Medical Office Space

    Palmdale CA Ave. Q And Trade Ctr Dr, Palmdale, CA 93551

    Estimated value:
    by Request
    View details
    2231 Palmdale Blvd
    Medical Office Space

    2231 Palmdale Blvd, Palmdale, CA 93550

    Estimated value:
    by Request
    34,319 sqft
    View details
    Avenue O
    Medical Office Space

    0 Avenue O, Palmdale, CA 93551

    Estimated value:
    by Request
    4.04 AC lot
    View details
    635 Commerce Ave
    Medical Office Space

    635 Commerce Ave, Palmdale, CA 93551

    Estimated value:
    by Request
    5,000 sqft 1.00 AC lot
    View details
    10Th St
    Neighborhood centers

    0 10Th St, Palmdale, CA 93551

    Estimated value:
    by Request
    View details
    921 Palmdale Blvd
    Medical Office Space

    921 Palmdale Blvd, Palmdale, CA 93550

    Estimated value:
    by Request
    5,518 sqft
    View details
    833 Auto Ctr Dr
    MEDICAL BUILDING

    833 Auto Ctr Dr, Palmdale, CA 93551-4488

    Estimated value:
    $1,475,000
    6,550 sqft 5.56 AC lot
    View details
    847 Auto Ctr Dr
    MEDICAL BUILDING

    847 Auto Ctr Dr, Palmdale, CA 93551-4490

    Estimated value:
    $870,000
    3,820 sqft 5.56 AC lot
    View details
    843 Auto Ctr Dr
    MEDICAL BUILDING

    843 Auto Ctr Dr, Palmdale, CA 93551-4489

    Estimated value:
    $1,860,000
    8,470 sqft 5.56 AC lot
    View details

    Palmdale, CA Medical Office Space Market Trends and Statistics

    Explore 23 medical office space for sale in Palmdale, CA, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 26,950 square feet of properties for sale, with an estimated market value of $3,950,000.

    Sale prices for medical spaces in Palmdale, CA average $3,950,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Top Commercial Asset Segments

    Commercial property segments ranked by active listings on the market

    Office Units 22
    Office buildings 13
    Medical Office Space 10
    Coworking space 2

    Demographics Overview

    Population 186K
    Population Growth (5Y) +8.7%
    Median Household Income $82,536
    College Educated 13.7%

    High-Yield Neighborhoods for Investment

    Identify Palmdale submarkets with the highest inventory density on the market and evaluate the average listing prices of real estate assets

    Neighborhood Average Price
    93551 $4M

    Taxes & Financing

    Tax Rate (average for all types) 1.59%
    Property Tax per SF $32.01 per SF
    Tax Rate vs County Average 0.33 pp above county avg
    Average Loan-to-Value 65.0%

    Listings Trend

    New vs delisted commercial listings in Los Angeles County

    New Delisted

    Total CRE Inventory on Market (SF)

    Average Property Price per SF

    For-sale pricing trends across core commercial property types in Los Angeles County

    Residential Income

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    5022 W Ave N, ste 102, Box 180 Palmdale, CA 93551
    Phone: 18002708770
    www.jpBroker.com

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