Palmdale, CA Office Spaces for Lease

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Lancaster, CA Acton, CA Agua Dulce, CA Santa Clarita, CA Castaic, CA Rosamond, CA Tujunga, CA San Jose, CA

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Updated: Aug 15, 2025

Front-Facing Desk Space in Shopping Center

533 E Palmdale Boulevard, Palmdale, CA 93550

$550/Mo

1,100 sqft

Desk space for rent in a well‑established shopping center in Palmdale
Storefront on Palmdale Blvd
Building constructed with concrete
Central heating and central air conditioning with natural gas
Asphalt roof

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Updated: Sep 29, 2025

Desk in Shared Office Suite

533 E Palmdale Boulevard, Palmdale, CA 93550

$450/Mo

1,000 sqft

Shopping center on Palmdale Blvd
Office desk for rent inside includes space for two clients, one chair, and a metal filing cabinet
Includes internet service
Desk can be used for DMV, insurance, or loans

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Move-In Ready Palmdale Office Space

4621 S Avenue, Palmdale, CA 93552

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2,072 sqft

Multiple suites available in Palmdale, CA, ready for occupancy.

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Remodeled Retail/Office Suites

2140 E Palmdale Blvd, Palmdale, CA 93550

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7,000 sqft

Recently remodeled retail/office suites in an established shopping center with storefront glass and rear delivery doors.

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Palmdale Office Suite For Rent

38700 W 5th Street, Palmdale, CA 93551

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1,400 sqft

Move-in ready office suite in Palmdale Business Park.

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SIERRA HIGHWAY BUSINESS PLAZA FOR OFFICES, FLEX

190 Sierra Ct, Palmdale, CA 93550

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200 sqft

Sierra Highway Plaza

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Palmdale Office Building For Lease

847 Auto Center Dr, Palmdale, CA 93551

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2,755 sqft

Office building with 2,755 SF available for lease.

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Palmdale Office Space Available

38660 Medical Center Dr., Palmdale, CA 93551

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59,577 sqft

Office suites available for lease in Palmdale, California.

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Move-in Ready Office Suite

38700 W 5th Street E, Palmdale, CA 93551

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1,400 sqft

Professional office suite for rent in Palmdale Business Park.

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Suburban Office Complex For Rent

39959 Sierra Hwy, Palmdale, CA 93550

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Two-story office complex with modern glass façade and landscaping.

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Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 10 Active listings in Palmdale, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 11 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

New Warehouse/Office Plaza in Lancaster

1133 W Ave L12, Lancaster, CA 93534

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5,680 sqft

New construction warehouse and office spaces available for lease.

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Lancaster Office/Flex Space Available

42913 Capital Drive, Lancaster, CA 93535

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3,298 sqft

Move-in ready office with roll-up door in Lancaster Business Park.

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Santa Clarita Office Space Available

27651 Lincoln Place, Santa Clarita, CA 91387

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30,732 sqft

Three-story office building in Santa Clarita with modern amenities.

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Canyon Country Retail Space Available

Santa Clarita, CA 91387

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17,000 sqft

Upscale live-work community with over 165,000 SF retail space.

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Similar Spaces for Sale in Palmdale, CA

Consider Similar Space for Sale. We found 11 Spaces matching your search parameters.

Live-Work Office-Flex Property

38960 12th Street E, Palmdale, CA 93550

$595,000

700 sqft 4.86 AC lot

Office-Flex live-work property on a fully fenced 4.86-acre parcel with a one-bedroom home, shop with power, and RV hookups.

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Palmdale Commercial Investment Opportunity

1309 E Palmdale Boulevard, Palmdale, CA 93550

$1,449,900

13,100 sqft 0.88 AC lot

Three office buildings on one lot near Downtown Palmdale.

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Palmdale Mixed-Use Investment Opportunity

38262 6th E, Palmdale, CA 93550

$562,000

3,228 sqft 0.16 AC lot

Mixed-use property with income potential in a prime location.

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Medical Office Investment Opportunity

450 W Palmdale, Palmdale, CA 93551

$3,950,000

13,200 sqft

Two buildings near Palmdale Regional Medical Center for sale.

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Office/Warehouse Condo in Palmdale

650 Commerce Avenue, Unit D, Palmdale, CA 93551

$435,000

2,427 sqft 5.29 AC lot

2,430 SF office/warehouse condo in excellent condition, built in 2007.

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Palmdale Freestanding Commercial Building

38423 9th St E, Palmdale, CA 93550

$989,000

3,500 sqft 0.20 AC lot

Well-maintained commercial building in Palmdale, ideal for owner-users or investors.

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Palmdale Freestanding Office Building

921 East Palmdale Boulevard, Palmdale, CA 93550

$1,100,000

5,518 sqft

Freestanding office building with frontage on Palmdale Boulevard.

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Palmdale DaVita For Sale

38454 5th St W, Palmdale, CA 93551

$6,442,755

13,750 sqft 1.46 AC lot

DaVita with long-term lease in Palmdale, California.

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Remodeled Retail/Office Suite

2140 E Palmdale Boulevard Unit L, Palmdale, CA 93550

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5,269 sqft

Recently remodeled turn-key retail and office suite with floor-to-ceiling storefront glass and covered pedestrian entry.

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Remodeled Retail/Office Suite

2140 E Palmdale Boulevard Unit M, Palmdale, CA 93550

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1,731 sqft

Recently remodeled suite with floor-to-ceiling glass storefronts, ADA restrooms and a kitchenette, within an established shopping center.

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Multi-Tenant Office Building

T-950 E Palmdale Boulevard, Palmdale, CA 93550

$1,990,000

Multi-tenant office property offers income in place with convenient access and ample parking off a highly visible corridor.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Service Commercial Land For Rent

1798 Hanford Armona Road, Hanford, CA 93230

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3-acre service commercial land in high-traffic Hanford location.

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Neighborhood Commercial Land for Development

2040 Prado Road, San Luis Obispo, CA 93401

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Develop a neighborhood commercial site with retail, office, and medical uses, positioned for strong freeway visibility.

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High Visibility Land For Lease

1400 Willow Pass Rd, Concord, CA 94520

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1 sqft

1.41 acres at signalized intersection available for ground lease.

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Build-to-Suit Corner Commercial Land

996 E 1st Avenue, Chico, CA 95926

$5,000/Mo

Corner commercial land with power onsite and city services on the street for a customizable build-to-suit project.

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Palmdale, CA Office Spaces Market Trends and Statistics

Explore Office Spaces leasing options in Palmdale, CA with 10 listings featured on our commercial real estate exchange. The current inventory includes 3,900 square feet of properties with an estimated lease value of $13.90 SF/Yr.

Estimated lease rates for Office Spaces in Palmdale, CA begin at $1.00 SF/Yr, with an average of $3.48 SF/Yr and extend to $6 SF/Yr.

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