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    Palmdale, CA Office Properties & Spaces for Lease

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    Los Angeles, CA San Diego, CA San Francisco, CA
    12 results
    Palmdale Office Space For Rent
    $550 /Mo
    1,100 SF

    Palmdale Office Space For Rent

    533 E Palmdale Boulevard, Palmdale, CA 93550

    Office space for rent in Palmdale shopping center.

    • Storefront desk space in a well‑established shopping center.
    • Prime location on Palmdale Blvd.
    • Suitable for Real Estate, Real Estate Loans, Insurance, Legal Desk, Immigration, etc.
    • Central heating (Natural Gas) and Central Air cooling.
    • Concrete construction.
    Updated: Aug 15, 2025
    View details
    Move-In Ready Palmdale Office Space
    $1.00 SF/Yr
    2,072 SF

    Move-In Ready Palmdale Office Space

    4621 S Avenue, Palmdale, CA 93552

    Move-in ready office space available for lease in Palmdale.

    • Move‑in ready office space
    • Multiple vacant suites available
    • Former Realty office layout featuring a bullpen, offices, and restroom
    • Glass storefront for great visibility
    • Built in 2008
    Updated: Mar 27
    View details
    SIERRA HIGHWAY BUSINESS PLAZA FOR OFFICES, FLEX
    $1.00 SF/Yr

    SIERRA HIGHWAY BUSINESS PLAZA FOR OFFICES, FLEX

    Sierra Highway Plaza

    190 Sierra Ct, Palmdale, CA 93550
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    Office Space in Palmdale Center
    $450 /Mo
    1,000 SF

    Office Space in Palmdale Center

    Desk for rent in Palmdale shopping center, internet included.

    533 E Palmdale Boulevard, Palmdale, CA 93550
    View details
    New Medical Office Space
    $2 SF/Yr
    10,000 SF

    New Medical Office Space

    Medical office space for lease in Palmdale, California.

    635 Commerce Avenue, Palmdale, CA 93551
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    Freeway Business Plaza For Lease
    $1,400 /Mo

    Freeway Business Plaza For Lease

    Freeway Business Plaza For Lease

    41250 12th St West #E-1, Palmdale, CA 93551
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    Palmdale Office Building For Lease
    Contact for pricing
    2,755 SF

    Palmdale Office Building For Lease

    Office building with 2,755 SF available for lease.

    847 Auto Center Dr, Palmdale, CA 93551
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    Medical Office Space Available
    Contact for pricing

    Medical Office Space Available

    New medical office building in Antelope Valley, Los Angeles.

    42155 11th Street West, Palmdale, CA 93551
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    Palmdale Office Space Available
    Contact for pricing
    59,577 SF

    Palmdale Office Space Available

    Office suites available for lease in Palmdale, California.

    38660 Medical Center Dr., Palmdale, CA 93551
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    Commercial Space in Palmdale, CA
    Contact for pricing

    Commercial Space in Palmdale, CA

    Commercial space available in growing Palmdale, Los Angeles County.

    520 - 540 Palmdale, Palmdale, CA 93551
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    Move-in Ready Palmdale Office Space
    $1.50 SF/Yr
    1,400 SF

    Move-in Ready Palmdale Office Space

    Professional office suite in Palmdale Business Park, ready now.

    38700 W 5th Street, Palmdale, CA 93551
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    Suburban Office Complex For Rent
    Contact for pricing

    Suburban Office Complex For Rent

    Two-story office complex with modern glass façade and landscaping.

    39959 Sierra Hwy, Palmdale, CA 93550
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    Based on your search, we've compiled 32 Potential Opportunities for your consideration. Besides 12 Active listings in Palmdale, CA, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 12 Properties for Sales.

    Explore Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Move-In Ready Office Space
    $1.25 SF/Yr

    Move-In Ready Office Space

    Office space featuring a lobby, reception area, and private offices.

    42311 10th St W, Lancaster, CA 93534
    View details
    Santa Clarita Office Space Available
    $2 SF/Yr
    30,732 SF

    Santa Clarita Office Space Available

    Three-story office building in Santa Clarita with modern amenities.

    27651 Lincoln Place, Santa Clarita, CA 91387
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    Canyon Country Retail Space Available
    Contact for pricing
    17,000 SF

    Canyon Country Retail Space Available

    Upscale live-work community with over 165,000 SF retail space.

    Santa Clarita, CA 91387
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    Freestanding Building in Mid-Cities Location
    Contact for pricing
    6,500 SF

    Freestanding Building in Mid-Cities Location

    Freestanding building with convenient freeway access and modern amenities.

    42142 7th St W, Lancaster, CA 93534
    View details

    Explore Similar Spaces for Sale in Palmdale, CA

    Consider Similar Space for Sale. We found 12 Spaces matching your search parameters.

    Versatile Mixed-Use Property, Palmdale
    $595,000
    700 SF

    Versatile Mixed-Use Property, Palmdale

    4.86-acre mixed-use property with live/work setup near downtown Palmdale.

    38960 12th Street E, Palmdale, CA 93550
    View details
    Palmdale Land with Development Potential
    $180,000
    1.00 Acre

    Palmdale Land with Development Potential

    Two adjacent parcels totaling 43,449 sq ft in Palmdale, CA.

    Sierra Highway, Palmdale, CA 93550
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    Palmdale Office Building Investment
    $1,449,900
    13,100 SF

    Palmdale Office Building Investment

    Three office buildings on a single lot, great investment opportunity.

    1309 E Palmdale Boulevard, Palmdale, CA 93550
    View details
    Palmdale Mixed-Use Investment Opportunity
    $567,000
    3,228 SF

    Palmdale Mixed-Use Investment Opportunity

    Mixed-use property with income potential in a prime location.

    38262 6th E, Palmdale, CA 93550
    View details
    Renovated Office Building in Palmdale
    $885,000
    0.23 Acres

    Renovated Office Building in Palmdale

    Newly renovated office building in Palmdale's prime commercial corridor.

    465 E Palmdale Boulevard, Palmdale, CA 93550
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    Office/Warehouse Condo in Palmdale
    $435,000
    2,427 SF

    Office/Warehouse Condo in Palmdale

    2,430 SF office/warehouse condo in excellent condition, built in 2007.

    650 Commerce Avenue, Unit D, Palmdale, CA 93551
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    Palmdale Freestanding Office Building
    $1,100,000
    5,518 SF

    Palmdale Freestanding Office Building

    Freestanding office building with frontage on Palmdale Boulevard.

    921 East Palmdale Boulevard, Palmdale, CA 93550
    View details
    Palmdale Freestanding Commercial Building
    $989,000
    3,500 SF

    Palmdale Freestanding Commercial Building

    Well-maintained commercial building in Palmdale, ideal for owner-users or investors.

    38423 9th St E, Palmdale, CA 93550
    View details
    New Class A Medical Office
    Contact for pricing
    24,600 SF

    New Class A Medical Office

    New 24,600 SF Class A medical office building.

    42155 11th Street West, Palmdale, CA 93551
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    Palmdale DaVita For Sale
    $6,442,755
    13,750 SF

    Palmdale DaVita For Sale

    DaVita with long-term lease in Palmdale, California.

    38454 5th St W, Palmdale, CA 93551
    View details
    Palmdale Mixed-Use Industrial Building
    $1,700,000
    8,320 SF

    Palmdale Mixed-Use Industrial Building

    8,320 SF mixed-use building in Palmdale Industrial Park.

    608 E Rancho Vista Blvd, Palmdale, CA 93550
    View details
    Palmdale Boulevard Office Space
    $1,100,000
    5,518 SF

    Palmdale Boulevard Office Space

    5,518 SF office space available for purchase.

    921 E Palmdale Blvd, Palmdale, CA 93550
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Prime Fontana Commercial Land Lease
    $0.01 SF/Yr
    1,565 SF

    Prime Fontana Commercial Land Lease

    4.33-acre commercial land for ground lease in Fontana, CA.

    16203 Foothill Boulevard, Fontana, CA 92335
    View details
    Prime Commercial Land for Lease
    Contact for pricing
    75,000 SF

    Prime Commercial Land for Lease

    Highly visible 3.59-acre commercial land in San Luis Obispo.

    2040 Prado Road, San Luis Obispo, CA 93401
    View details
    Chico Commercial Land For Lease
    $5,000 /Mo
    9,000 SF

    Chico Commercial Land For Lease

    Prime corner lot in Chico for build to suit.

    996 E 1st Avenue, Chico, CA 95926
    View details
    Grand Junction Commercial Land Lease
    $9,656 /Mo

    Grand Junction Commercial Land Lease

    0.74 acre commercial land for lease in Grand Junction.

    Highway 6&50, Grand Junction, CO 81505
    View details

    Palmdale, CA Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Palmdale, CA with 12 listings featured on our commercial real estate exchange. The current inventory includes 994,039,200 square feet of properties with an estimated lease value of $18 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Palmdale, CA begin at $1.00 SF/Yr, with an average of $3 SF/Yr and extend to $6 SF/Yr.
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    Browse Office properties & Spaces for Lease Near Palmdale, CA

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    Most Searched ZIP Codes in Palmdale, CA

    • 93551
    • 93550
    • 93552

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