Hesperia, CA Office Units for Rent & Lease

Updated: Mar 4

Flexible Mixed-Use Commercial Space

14920 Main St Unit #3, Hesperia, CA 92345

$2,000/Mo

1,000 SF mixed‑use commercial unit
Suitable for retail, professional office, studio, or service‑based use
Located at 14920 Main St Unit #3, Hesperia, CA 92345
Built in 2015
Owner pays water, trash, and sewer service

View details

Updated: Jul 9

Retail Suite with Office Layout

16455 Main Street, Hesperia, CA 92345

Contact for pricing

Suite 15 with approximately 1,500 SF available April 2026
Interior includes reception, two private offices, two additional rooms, open workspace, and one restroom
Located within The Hesperia Center along Main Street
Immediate access to Hesperia Road and the broader High Desert trade area
On‑site parking and signage exposure along a high‑traffic commercial corridor

View details

Office Suite with Warehouse Space

16490 Walnut Street, Hesperia, CA 92345

Contact for pricing

Climate-controlled office and warehouse setup with ample parking and additional storage above, suited to service and professional uses.

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Medical Office Suite with Three Offices

17151 Main Street B, Hesperia, CA 92345

$2,050/Mo

6,000 sqft

Suite B offers three offices and a waiting room for administrative or medical-related use.

View details

Turn-Key Dental Office Suites

18361 Bear Valley Road 2&3, Hesperia, CA 92345

$3,200/Mo

10,246 sqft

Turn-key dental office suites available in a multi-tenant plaza with street visibility and pylon signage.

View details

Office Suite with Two Offices

15800 Main St Unit 160, Hesperia, CA 92345

$1,548/Mo

26,942 sqft

In-line office space within a multi-tenant plaza, featuring two completed offices and pylon signage.

View details

Mezzanine Office Suite

B-12720 Main, Hesperia, CA 92345

$2,544/Mo

1,413 sqft

Configured with multiple private offices, two restrooms, and monument signage.

View details

Medical Office Suite with Waiting Room

B-17151 Main St, Hesperia, CA 92345

$2,050/Mo

1,500 sqft

Multi-tenant building offers a built-out suite with three offices and a waiting room.

View details

Office Suites in Corner Location

F-12050 I Ave, Hesperia, CA 92345

$800/Mo

550 sqft

Two office suites are available in an I Ave Tower building with corner visibility and on-site signage.

View details

Hesperia Office Space Available

12050 I Avenue F, Hesperia, CA 92345

$800/Mo

550 sqft

Office space for rent in central Hesperia location.

View details

Hesperia Office Space For Rent

15659 Bear Valley Rd, Hesperia, CA 92345

$1,600/Mo

1,000 sqft

Centrally located office space on Bear Valley Rd for rent.

View details

Updated Retail Space

16183 Main, Hesperia, CA 92345

Contact for pricing

3,560 sqft

Flexible storefront suite with an open layout, display glazing, private restroom, and rear storage area.

View details

Office Unit With Private Offices

10178 I Ave C, Hesperia, CA 92345

Contact for pricing

28,710 sqft

Commercial suite with a lobby, three private offices, and an open assembly room.

View details

Move-In Ready Office Unit

16455 Main St Unit 15, Hesperia, CA 92345

Contact for pricing

1,500 sqft

Approximately 1,500 SF with reception, private offices, open workspace, additional rooms, and a restroom.

View details

Storefront Office Suite with Reception

D-10918 Hesperia Rd, Hesperia, CA 92345

Contact for pricing

1,150 sqft

Move-in-ready suite with direct storefront access, reception space, multiple private rooms, and an in-suite restroom.

View details

Highly Visible Multi-Unit Office Building

16490 Walnut St, Hesperia, CA 92345

Contact for pricing

6,000 sqft 0.88 AC lot

Multi-unit office building with ample parking and move-in ready spaces.

View details

Clock Tower Professional Center Offices

16501 Walnut St Unit 3, Hesperia, CA 92345

Contact for pricing

11,690 sqft

Multi-tenant office suites for lease in Hesperia, California.

View details

Storefront Suite with Private Rooms

10918 Hesperia Road, Hesperia, CA 92345

Contact for pricing

1,150 sqft

Professional interior includes reception space, multiple private rooms, and an in-suite restroom.

View details

Hesperia Center Retail/Office Suites

16455 Main St, Hesperia, CA 92345

Contact for pricing

1,500 sqft

Retail and office suites available for lease in Hesperia.

View details

Medical Office Suite with Exam Rooms

H-17450 Main St, Hesperia, CA 92345

$3,700/Mo

2,177 sqft

Configured for patient-facing operations with reception, treatment space, private offices, and four restrooms.

View details

Medical Office Suite with Exam Rooms

17450 Main Street H, Hesperia, CA 92345

$3,700/Mo

2,177 sqft

Single-story professional-center space includes patient reception, treatment areas, private offices, and multiple restrooms.

View details

Medical Office Suite with Private Entrance

D-17450 Main St, Hesperia, CA 92345

$2,448/Mo

Medical office suite with exam rooms, kitchenette, and dedicated front and rear entry for staff and patient access.

View details

Small Medical Office Suite

B-17450 Main St, Hesperia, CA 92345

$909.50/Mo

535 sqft

Single-story professional center unit with front and rear access, shared parking, and nearby bus service.

View details

Private Medical Office Suite

C-15462 Main St, Hesperia, CA 92345

Contact for pricing

678 sqft

Private office accommodation with exterior access, a dedicated office, open workspace, and an on-site restroom.

View details

Hesperia, CA Office Units Lease Rates & Market Statistics

Explore 27 Office Units for lease in Hesperia, CA on Realmo, a commercial real estate exchange covering the Hesperia area. The current inventory totals 115,028 square feet of properties — an average of ~4,250 SF per listing.

Asking lease rates for Office Units in Hesperia start at $3.75 SF/Yr, average $16.12 SF/Yr, and reach $21.61 SF/Yr at the top of the market. That's a 6x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $16.12 SF/Yr, the local average runs 33% below California's state average of $24.20 SF/Yr.

Hesperia accounts for 6% of the 422 office units currently available across San Bernardino County, where nearby markets include Ontario and Rancho Cucamonga. Office Units make up 87% of the 31 Office Spaces currently for lease in Hesperia, with asking rates in line with the citywide Office Spaces average. Tenants comparing options may also consider Medical Office Space (12 listings) elsewhere in the Hesperia market.