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Greenwood County, SC Office Properties & Spaces for Sale

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Versatile Commercial Building, Greenwood SC
$159,000
1,722 SF

Versatile Commercial Building, Greenwood SC

1601 E Cambridge Ave, Greenwood, SC 29646

Adaptable commercial building with high visibility and flexible build-out options.

  • High‑visibility corner location with strong road presence
  • Large, open interior with high ceilings and exposed framing, ideal for customization
  • Flexible build‑out options suitable for retail, light industrial, workshop, studio, storage, or office conversion
  • Generous lot space for parking, storage, or expansion
  • Durable block construction
Updated: Feb 3
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Historic Uptown Greenwood Commercial Property
$749,000
4,684 SF

Historic Uptown Greenwood Commercial Property

206 Main St, Greenwood, SC 29649

Versatile commercial space in a vibrant historic district with unique features.

  • Prime Location: Situated in the heart of Uptown Greenwood with high visibility and foot traffic.
  • Versatile Space: Just under 5,000 sqft with a flexible layout suitable for retail, office, or mixed‑use purposes. Includes seven private office suites, a shared kitchenette, and a large basement.
  • Historic Charm: Features original hardwood floors, ghost murals (including a vintage Coca‑Cola mural), and architectural details reflecting its 1917 origins.
  • Ample Parking: Benefits from an expansive city‑owned front lot providing abundant parking.
  • Turnkey Opportunity: Includes all remaining furnishings upstairs, making it ready for a new business/owner.
Updated: Sep 9, 2025
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Greenwood Commercial Building with Warehouse
$395,000
10,000 SF

Greenwood Commercial Building with Warehouse

Office, showroom, and warehouse on a large corner lot.

1201 Cambridge Ave, Greenwood, SC 29649
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Uptown Greenwood Multi-Use Corner Building
$750,000
5,308 SF

Uptown Greenwood Multi-Use Corner Building

Three-level commercial building with retail, office, and storage space.

202 Main St, Greenwood, SC 29646
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Based on your search, we've compiled 245 Potential Opportunities for your consideration. Besides 4 Active listings in Greenwood County, SC, we suggest exploring several alternatives: similar 237 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Greenwood Commercial Acreage Opportunity
$4,300,000
11.46 Acres

Greenwood Commercial Acreage Opportunity

11.46 acres of commercial land in Greenwood, South Carolina.

508 Old Abbeville Hwy, Greenwood, SC 29646
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Greenwood Commercial Corner Lot Opportunity
$174,000
0.54 Acres

Greenwood Commercial Corner Lot Opportunity

Prime commercial lot in Greenwood's active corridor, ideal for development.

441/443 Calhoun Ave, Greenwood, SC 29649
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Commercial Land on Montague Ave
$135,000
0.49 Acres

Commercial Land on Montague Ave

Half-acre commercial tract in high-traffic location, ready for business.

1438 Montague Avenue Ext, Greenwood, SC 29649
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Commercial Lots on High-Traffic Highway
$149,000
1.73 Acres

Commercial Lots on High-Traffic Highway

Prime commercial land with high visibility and growth potential.

2611 Hwy 25S, Greenwood, SC 29646
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Explore Off-Market Properties in Greenwood County, SC

Consider similar Off-Market properties in Greenwood County, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

1202 Hwy 72nd W

1202 Hwy 72nd W

MEDICAL BUILDING • 4,590 SF
Value Estimation by Request
1202 Hwy 72nd W, Greenwood, SC 29649-1816
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102 Katie Ct

102 Katie Ct

MEDICAL BUILDING • 6,521 SF
Value Estimation by Request
102 Katie Ct, Greenwood, SC 29646-4068
View details
810 Greenwood Ave

810 Greenwood Ave

OFFICE BUILDING • 2,336 SF
Value Estimation by Request
810 Greenwood Ave, Ware Shoals, SC 29692-1234
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123 High St

123 High St

OFFICE BUILDING • 1,862 SF
Value Estimation by Request
123 High St, Greenwood, SC 29649-1925
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1013 Spg St

1013 Spg St

MEDICAL BUILDING • 12,541 SF
Value Estimation by Request
1013 Spg St, Greenwood, SC 29646
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212 Oak Ave

212 Oak Ave

OFFICE BUILDING • 4,124 SF
Value Estimation by Request
212 Oak Ave, Greenwood, SC 29646-2625
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231 Hampton Ave Ste F

231 Hampton Ave Ste F

OFFICE BUILDING • 750 SF
Value Estimation by Request
231 Hampton Ave Ste F, Greenwood, SC 29646-2299
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200 Main N St

200 Main N St

OFFICE BUILDING • 2,000 SF
Value Estimation by Request
200 Main N St, Greenwood, SC 29646-2242
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1226 Spg St

1226 Spg St

MEDICAL BUILDING • 3,135 SF
Value Estimation by Request
1226 Spg St, Greenwood, SC 29646-3835
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327 Main St, Unit 6

327 Main St, Unit 6

OFFICE BUILDING • 1,817 SF
Value Estimation by Request
327 Main St, Greenwood, SC 29646-1601
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327 Main St, Unit 3

327 Main St, Unit 3

OFFICE BUILDING • 1,817 SF
Value Estimation by Request
327 Main St, Greenwood, SC 29646-1601
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1402 Hwy 72nd W

1402 Hwy 72nd W

OFFICE BUILDING • 6,388 SF
Value Estimation by Request
1402 Hwy 72nd W, Greenwood, SC 29649-1822
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1201 Cambridge E Ave

1201 Cambridge E Ave

OFFICE BUILDING • 10,207 SF
Value Estimation
$565,000
1201 Cambridge E Ave, Greenwood, SC 29646-3071
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339 Grace St

339 Grace St

OFFICE BUILDING • 864 SF
Value Estimation by Request
339 Grace St, Greenwood, SC 29649-2417
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97 Greenwood Ave

97 Greenwood Ave

OFFICE BUILDING • 1,781 SF
Value Estimation by Request
97 Greenwood Ave, Ware Shoals, SC 29692-1535
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1404 Edgefield St

1404 Edgefield St

MEDICAL BUILDING • 3,600 SF
Value Estimation by Request
1404 Edgefield St, Greenwood, SC 29646-4014
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219 Waller Ave

219 Waller Ave

OFFICE BUILDING • 9,420 SF
Value Estimation
$520,000
219 Waller Ave, Greenwood, SC 29646
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128 Maxwell Ave

128 Maxwell Ave

OFFICE BUILDING • 2,628 SF
Value Estimation by Request
128 Maxwell Ave, Greenwood, SC 29646-2641
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201 Hampton Ave Ste C

201 Hampton Ave Ste C

OFFICE BUILDING • 1,050 SF
Value Estimation by Request
201 Hampton Ave Ste C, Greenwood, SC 29646-2271
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711 Montague Ave

711 Montague Ave

MEDICAL BUILDING • 2,410 SF
Value Estimation by Request
711 Montague Ave, Greenwood, SC 29649-1440
View details

Greenwood County, SC Office Properties & Spaces Investment Opportunities Market Analysis

Explore 241 office properties & spaces for sale in Greenwood County, SC, showcased through 4 active listings on our real estate platform. These investment opportunities span a total of 4,832,895 square feet of properties for sale, with an estimated market value of $43,669,000.

Prices for office spaces in Greenwood County, SC start at $50,000, averaging $949,326, and reaching up to $12,245,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

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