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South Euclid, OH Office Spaces for Sale

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Mayfield Road Office Building Site
Updated: Sep 10, 2025
Mayfield Road Office Building Site

4568 Mayfield Road, South Euclid, OH 44121

Contact for pricing
1 sqft
Prime Mayfield Road location
1.6362 acre parcel available for ground lease
Existing office building
Development opportunity
High‑traffic area
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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center
Based on your search, we've compiled 51 Potential Opportunities for your consideration. Besides 1 Active listings in South Euclid, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 42 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Flex & Warehouse Facility with Furnished Offices
Flex & Warehouse Facility with Furnished Offices

1490 East 191st Street, Euclid, OH 44117

Contact for pricing
46,000 sqft 0.48 AC lot

Move-in ready, air-conditioned flex space with 18’ clear warehouse, docks and drive-ins, plus furnished offices and lab-ready buildout.

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Two-Story Office Building
Two-Story Office Building

18419 Euclid Ave, Cleveland, OH 44112

Contact for pricing
20,970 sqft 0.83 AC lot

Built in 1955, this two-story office building offers updated commercial space and surface parking on 0.83 acres.

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Historic Corner Office Building
Historic Corner Office Building

2860 Noble Road, Cleveland, OH 44121

$275,000

Fully remodeled office building with historic character, including new roof, updated HVAC, replacement windows, and a mini-kitchen.

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Euclid Avenue Office Space Available
Euclid Avenue Office Space Available

24701 Euclid Ave, Euclid, OH

Contact for pricing
61,481 sqft 38.86 AC lot

61,481 SF office building with ample parking.

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

B-2A Commercial Corner Lot
B-2A Commercial Corner Lot

443 BROADWAY Avenue, Bedford, OH 44146

$48,000
0.18 AC lot

Corner commercial land with utilities at the street and public water and sewer service.

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Eastlake Marina District Land
Eastlake Marina District Land

35783 Lake Shore Boulevard, Eastlake, OH 44095

$765,000
5.66 AC lot

5.66 acres in Eastlake's Marina District, primed for development.

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Office/Medical Development Site
Office/Medical Development Site

V/L (1.32 Acres) Aurora Road, Solon, OH 44139

$1,400,000
1.75 AC lot

Clear commercial land with a thru-way connection to a Giant Eagle parking lot and Office/Medical zoning.

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Corner Commercial Land
Corner Commercial Land

Lost Nation Road, Willoughby, OH 44094

$750,000
7.72 AC lot

Corner development parcel opposite Lost Nation Airport with public water and sewer service.

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Off-Market Properties in South Euclid, OH

Consider similar Off-Market properties in South Euclid, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

4338 Mayfield Rd
MEDICAL BUILDING

4338 Mayfield Rd, South Euclid, OH 44121-3666

$345,000
Estimated value
1,840 sqft 0.25 AC lot
View details
1463 Warrensville Ctr Rd
OFFICE BUILDING

1463 Warrensville Ctr Rd, South Euclid, OH 44121-2674

$440,000
Estimated value
6,810 sqft 0.43 AC lot
View details
2121 Grn Rd
OFFICE BUILDING

2121 Grn Rd, South Euclid, OH 44121-3338

$1,445,000
Estimated value
12,122 sqft 0.36 AC lot
View details
2111 Grn Rd
OFFICE BUILDING

2111 Grn Rd, South Euclid, OH 44121-3350

$320,000
Estimated value
3,530 sqft 0.28 AC lot
View details
4070 Mayfield Rd
OFFICE BUILDING

4070 Mayfield Rd, South Euclid, OH 44121-3036

$340,000
Estimated value
3,406 sqft 0.28 AC lot
View details
4185 Glenridge Rd
OFFICE BUILDING

4185 Glenridge Rd, South Euclid, OH 44121-2801

$510,000
Estimated value
2,050 sqft 2.63 AC lot
View details
4226 Mayfield Rd
OFFICE BUILDING

4226 Mayfield Rd, South Euclid, OH 44121-3008

$60,000
Estimated value
1,590 sqft 0.08 AC lot
View details
1962 Warrensville Ctr Rd
OFFICE BUILDING

1962 Warrensville Ctr Rd, South Euclid, OH 44121-2635

$220,000
Estimated value
2,625 sqft 0.15 AC lot
View details
14055 Cedar Rd
OFFICE BUILDING

14055 Cedar Rd, South Euclid, OH 44118-3337

$2,300,000
Estimated value
22,983 sqft 1.33 AC lot
View details
4225 Mayfield Rd
OFFICE BUILDING

4225 Mayfield Rd, South Euclid, OH 44121-3000

$635,000
Estimated value
4,720 sqft 0.27 AC lot
View details
527 Grn Rd
OFFICE BUILDING

527 Grn Rd, South Euclid, OH 44121-2818

$350,000
Estimated value
1,980 sqft 1.50 AC lot
View details
4282 Mayfield Rd
OFFICE BUILDING

4282 Mayfield Rd, South Euclid, OH 44121-3016

$330,000
Estimated value
3,715 sqft 0.19 AC lot
View details
1481 Warrensville Ctr Rd
OFFICE BUILDING

1481 Warrensville Ctr Rd, South Euclid, OH 44121-2655

$585,000
Estimated value
8,742 sqft 0.40 AC lot
View details
4125 Mayfield Rd
MEDICAL BUILDING

4125 Mayfield Rd, South Euclid, OH 44121-3041

$245,000
Estimated value
1,312 sqft 0.20 AC lot
View details
4306 Mayfield Rd
OFFICE BUILDING

4306 Mayfield Rd, South Euclid, OH 44121-3632

$345,000
Estimated value
2,244 sqft 0.43 AC lot
View details
4568 Mayfield Rd
OFFICE BUILDING

4568 Mayfield Rd, South Euclid, OH 44121-4064

$2,130,000
Estimated value
18,864 sqft 1.48 AC lot
View details
4202 Mayfield Rd
OFFICE BUILDING

4202 Mayfield Rd, South Euclid, OH 44121-3008

$285,000
Estimated value
0.27 AC lot
View details
2120 Grn Rd
OFFICE BUILDING

2120 Grn Rd, South Euclid, OH 44121-3349

$1,330,000
Estimated value
10,296 sqft 0.39 AC lot
View details
4173 Mayfield Rd
OFFICE BUILDING

4173 Mayfield Rd, South Euclid, OH 44121-3043

$330,000
Estimated value
560 sqft 0.14 AC lot
View details
2054 Grn Rd
MEDICAL BUILDING

2054 Grn Rd, South Euclid, OH 44121-4243

$195,000
Estimated value
0.61 AC lot
View details
14077 Cedar Rd
OFFICE BUILDING

14077 Cedar Rd, South Euclid, OH 44118-3338

$2,685,000
Estimated value
23,124 sqft 0.57 AC lot
View details
14077 Cedar Rd
OFFICE BUILDING

14077 Cedar Rd, South Euclid, OH 44118-3338

$220,000
Estimated value
0.19 AC lot
View details
14077 Cedar Rd Ste, Unit 204
OFFICE BUILDING

14077 Cedar Rd Ste, South Euclid, OH 44118-3332

Unit 204
$240,000
Estimated value
0.23 AC lot
View details

South Euclid, OH Office Spaces Market Trends and Statistics

Explore 43 office spaces for sale in South Euclid, OH on our real estate platform. These investment opportunities span a total of 1 square feet of properties for sale.

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Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Office buildings 1

Demographics Overview

Population 73K
Population Growth (5Y) +1.2%
Median Household Income $76,012
College Educated 76.6%

Listings Trend

New vs delisted commercial listings in Cuyahoga County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Cuyahoga County

Residential Income

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