South Euclid, OH Office Spaces for Sale

List

Map

Euclid, OH Cleveland Heights, OH Cleveland, OH Lyndhurst, OH University Heights, OH East Cleveland, OH Richmond Heights, OH Highland Heights, OH

Updated: Sep 10, 2025

Mayfield Road Office Building Site

4568 Mayfield Road, South Euclid, OH 44121

Contact for pricing

1 sqft

Prime Mayfield Road location
1.6362 acre parcel available for ground lease
Existing office building
Development opportunity
High‑traffic area

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 51 Potential Opportunities for your consideration. Besides 1 Active listings in South Euclid, OH, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 42 Off-Market properties to explore as potential leads, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

Freestanding Brick Mixed-Use Building

15602 Waterloo, Cleveland, OH 44110

$240,000

2,276 sqft

Full basement and an included parking lot add functional flexibility to this commercial property.

View details

Freestanding Office Building

21950 Euclid Avenue, Euclid, OH 44117

$185,000

0.20 AC lot

Standalone commercial property with central air, forced-air heating, driveway parking, and a garage.

View details

Flex & Warehouse Facility with Furnished Offices

1490 East 191st Street, Euclid, OH 44117

Contact for pricing

46,000 sqft 0.48 AC lot

Move-in ready, air-conditioned flex space with 18’ clear warehouse, docks and drive-ins, plus furnished offices and lab-ready buildout.

View details

Medical Office Building with Surgery Center

464 Richmond Road, Cleveland, OH 44143

$1,000,000

0.60 AC lot

Established medical operations include an on-site surgery center and nurse training organization.

View details

Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

B-2A Commercial Corner Lot

443 BROADWAY Avenue, Bedford, OH 44146

$48,000

0.18 AC lot

B-2A-zoned parcel with public utilities located at the street.

View details

Eastlake Marina District Land

35783 Lake Shore Boulevard, Eastlake, OH 44095

$765,000

5.66 AC lot

5.66 acres in Eastlake's Marina District, primed for development.

View details

Corner Commercial Land

Lost Nation Road, Willoughby, OH 44094

$750,000

7.72 AC lot

Corner parcel with public water and sewer service.

View details

Corner Commercial Land

V/L Lost Nation Road, Willoughby, OH 44094

$750,000

7.72 AC lot

Corner acreage positioned for retail, office, business, warehouse, and other commercial concepts.

View details

Off-Market Properties in South Euclid, OH

Consider similar Off-Market properties in South Euclid, OH. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

MEDICAL BUILDING

4338 Mayfield Rd, South Euclid, OH 44121-3666

Estimated value:

$345,000

1,840 sqft 0.25 AC lot

View details

OFFICE BUILDING

1463 Warrensville Ctr Rd, South Euclid, OH 44121-2674

Estimated value:

$440,000

6,810 sqft 0.43 AC lot

View details

OFFICE BUILDING

2121 Grn Rd, South Euclid, OH 44121-3338

Estimated value:

$1,445,000

12,122 sqft 0.36 AC lot

View details

OFFICE BUILDING

2111 Grn Rd, South Euclid, OH 44121-3350

Estimated value:

$320,000

3,530 sqft 0.28 AC lot

View details

OFFICE BUILDING

4070 Mayfield Rd, South Euclid, OH 44121-3036

Estimated value:

$340,000

3,406 sqft 0.28 AC lot

View details

OFFICE BUILDING

4185 Glenridge Rd, South Euclid, OH 44121-2801

Estimated value:

$510,000

2,050 sqft 2.63 AC lot

View details

OFFICE BUILDING

4226 Mayfield Rd, South Euclid, OH 44121-3008

Estimated value:

$60,000

1,590 sqft 0.08 AC lot

View details

OFFICE BUILDING

1962 Warrensville Ctr Rd, South Euclid, OH 44121-2635

Estimated value:

$220,000

2,625 sqft 0.15 AC lot

View details

OFFICE BUILDING

14055 Cedar Rd, South Euclid, OH 44118-3337

Estimated value:

$2,300,000

22,983 sqft 1.33 AC lot

View details

OFFICE BUILDING

4225 Mayfield Rd, South Euclid, OH 44121-3000

Estimated value:

$635,000

4,720 sqft 0.27 AC lot

View details

OFFICE BUILDING

527 Grn Rd, South Euclid, OH 44121-2818

Estimated value:

$350,000

1,980 sqft 1.50 AC lot

View details

OFFICE BUILDING

4282 Mayfield Rd, South Euclid, OH 44121-3016

Estimated value:

$330,000

3,715 sqft 0.19 AC lot

View details

OFFICE BUILDING

1481 Warrensville Ctr Rd, South Euclid, OH 44121-2655

Estimated value:

$585,000

8,742 sqft 0.40 AC lot

View details

MEDICAL BUILDING

4125 Mayfield Rd, South Euclid, OH 44121-3041

Estimated value:

$245,000

1,312 sqft 0.20 AC lot

View details

OFFICE BUILDING

4306 Mayfield Rd, South Euclid, OH 44121-3632

Estimated value:

$345,000

2,244 sqft 0.43 AC lot

View details

OFFICE BUILDING

4568 Mayfield Rd, South Euclid, OH 44121-4064

Estimated value:

$2,130,000

18,864 sqft 1.48 AC lot

View details

OFFICE BUILDING

4202 Mayfield Rd, South Euclid, OH 44121-3008

Estimated value:

$285,000

0.27 AC lot

View details

OFFICE BUILDING

2120 Grn Rd, South Euclid, OH 44121-3349

Estimated value:

$1,330,000

10,296 sqft 0.39 AC lot

View details

OFFICE BUILDING

4173 Mayfield Rd, South Euclid, OH 44121-3043

Estimated value:

$330,000

560 sqft 0.14 AC lot

View details

MEDICAL BUILDING

2054 Grn Rd, South Euclid, OH 44121-4243

Estimated value:

$195,000

0.61 AC lot

View details

OFFICE BUILDING

14077 Cedar Rd, South Euclid, OH 44118-3338

Estimated value:

$2,685,000

23,124 sqft 0.57 AC lot

View details

OFFICE BUILDING

14077 Cedar Rd, South Euclid, OH 44118-3338

Estimated value:

$220,000

0.19 AC lot

View details

OFFICE BUILDING

14077 Cedar Rd Ste, South Euclid, OH 44118-3332

Unit 204

Estimated value:

$240,000

0.23 AC lot

View details

South Euclid, OH Office Spaces Market Trends and Statistics

Explore 43 office spaces for sale in South Euclid, OH on our real estate platform. These investment opportunities span a total of 1 square feet of properties for sale.

List

Map

Top Commercial Asset Segments

Commercial property segments ranked by active listings on the market

Demographics Overview

Population 73K

Population Growth (5Y) +1.2%

Median Household Income $76,012

College Educated 76.6%

Listings Trend

New vs delisted commercial listings in Cuyahoga County

New Delisted

Total CRE Inventory on Market (SF)

Average Property Price per SF

For-sale pricing trends across core commercial property types in Cuyahoga County

Residential Income

Need Help?

Reach out if you need assistance with Realmo tools or have questions about your listings

South Euclid, OH Office Spaces for Sale

4568 Mayfield Road, South Euclid, OH 44121

Opportunities in Nearby Cities

15602 Waterloo, Cleveland, OH 44110

21950 Euclid Avenue, Euclid, OH 44117

1490 East 191st Street, Euclid, OH 44117

464 Richmond Road, Cleveland, OH 44143

Potential Development Sites for Consideration

443 BROADWAY Avenue, Bedford, OH 44146

35783 Lake Shore Boulevard, Eastlake, OH 44095

Lost Nation Road, Willoughby, OH 44094

V/L Lost Nation Road, Willoughby, OH 44094

Off-Market Properties in South Euclid, OH

4338 Mayfield Rd, South Euclid, OH 44121-3666

1463 Warrensville Ctr Rd, South Euclid, OH 44121-2674

2121 Grn Rd, South Euclid, OH 44121-3338

2111 Grn Rd, South Euclid, OH 44121-3350

4070 Mayfield Rd, South Euclid, OH 44121-3036

4185 Glenridge Rd, South Euclid, OH 44121-2801

4226 Mayfield Rd, South Euclid, OH 44121-3008

1962 Warrensville Ctr Rd, South Euclid, OH 44121-2635

14055 Cedar Rd, South Euclid, OH 44118-3337

4225 Mayfield Rd, South Euclid, OH 44121-3000

527 Grn Rd, South Euclid, OH 44121-2818

4282 Mayfield Rd, South Euclid, OH 44121-3016

1481 Warrensville Ctr Rd, South Euclid, OH 44121-2655

4125 Mayfield Rd, South Euclid, OH 44121-3041

4306 Mayfield Rd, South Euclid, OH 44121-3632

4568 Mayfield Rd, South Euclid, OH 44121-4064

4202 Mayfield Rd, South Euclid, OH 44121-3008

2120 Grn Rd, South Euclid, OH 44121-3349

4173 Mayfield Rd, South Euclid, OH 44121-3043

2054 Grn Rd, South Euclid, OH 44121-4243

14077 Cedar Rd, South Euclid, OH 44118-3338

14077 Cedar Rd, South Euclid, OH 44118-3338

14077 Cedar Rd Ste, South Euclid, OH 44118-3332

South Euclid, OH Office Spaces Market Trends and Statistics

Top Commercial Asset Segments

Demographics Overview

Listings Trend

Total CRE Inventory on Market (SF)

Average Property Price per SF

Residential Income

Need Help?

Browse Office Spaces for Sale Near South Euclid, OH

Popular Searches in South Euclid, OH

Popular Categories

Most Searched ZIP Codes in South Euclid, OH

Select Neighborhood