Independence, MO Office Properties & Spaces for sale

Downtown Independence Commercial Building For Sale

$1,300,000

0.30 Acres

Downtown Independence Commercial Building For Sale

120 S Liberty St, Independence, MO 64050

Well-maintained commercial building in Downtown Independence, suitable for various uses.

Prime location in the heart of Downtown Independence with excellent visibility and accessibility.
Well‑maintained commercial building suitable for a variety of uses.
Newer roof (2 years old).
Relatively new HVAC system (5 years old).
Parking Lot included.

Updated: Dec 17, 2025

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Remodeled Commercial Space on High-Traffic

$250,000

0.20 Acres

Remodeled Commercial Space on High-Traffic

307 E 23Rd St, Independence, MO 64055

Affordable, remodeled commercial space with high visibility and business potential.

High‑traffic location on 23rd Street with HUGE business potential.
Fully remodeled interior and exterior.
Standalone commercial space with C‑2 zoning.
18' tall pole sign with HIGH visibility.
Multiple office spaces: 2 large, 1 open.

Updated: Dec 26, 2025

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$119,000

0.13 Acres

Reformed Office Space in Independence

Charming office space in a reformed residential home.

911 E 23Rd St, Independence, MO 64055

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$475,000

0.43 Acres

Commercial Building with Multiple Units

Commercial building with nine units, potential for $5,000+ monthly income.

3501 S Sterling Ave, Independence, MO 64052

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Independence Commercial Building For Sale

$365,000

0.28 Acres

Independence Commercial Building For Sale

3,456 SF commercial building on high-traffic corner lot.

13717 E 39Th St, Independence, MO 64055

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$449,000

0.17 Acres

Prime Office Building, Independence, MO

High-visibility office, ample parking, owner financing possible.

129 23Rd St, Independence, MO 64055

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$149,900

0.13 Acres

Prime Independence Office Space

Charming Office, Ideal Location, $149,900

911 23Rd St, Independence, MO 64055

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$399,000

0.96 Acres

Prime Independence Office Building

Updated Office Space, Huge Potential

301 M 291 Hwy, Independence, MO 64056

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$850,000

2.94 Acres

Prime Independence Office Building

Spacious Office Building on 3 Acres

11610 Truman Rd, Independence, MO 64050

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$500,000

Independence Office Building & Vet Clinic

Established Vet Practice, Great Opportunity

13717 39Th St, Independence, MO 64055

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$850,000

2.94 Acres

Truman Road Warehouse - $850K

Prime Independence Warehouse, 2-Story, 2.94 Acres

11610 Truman Rd, Independence, MO 64050

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$850,000

Prime Independence Commercial Space

Versatile 20,000 sq ft building, great location.

4621 Shrank Dr, Independence, MO 64055

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Executive Office Building, Independence, MO

$2,100,000

33,624 SF

Executive Office Building, Independence, MO

Class B Office, 33,624 SF, $2.1M

3445 Rte 291, Independence, MO 64057

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$595,000

10,500 SF

Independence Office Building - $595,000

10,500 SF Office Building, Vacant & Ready

4228 Hocker Ave, Independence, MO 64055

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200,000 SF

Medical Suites Near Centerpoint Medical

Divisible medical suites with hospital access and ample parking.

19550 E 39Th St, Independence, MO 64057

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$490,000

10,500 SF

Independence Office Building For Sale

Three-story office building with divisible floors and separate entrances.

4228 S Hocker Dr, Independence, MO 64055

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4,084 SF

Office Building with Drive-Through

4,084 SF building on 0.45 acre lot in Independence, MO.

11507 E 23Rd St S, Independence, MO 64052

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$950,000

14,882 SF

Remodeled Office Building For Sale

Remodeled office building with highway access in Independence, Missouri.

13720 E 42Nd Ter S, Independence, MO 64055

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Office Building Sale Leaseback Opportunity

$1,450,000

37,080 SF

Office Building Sale Leaseback Opportunity

Office building with leaseback opportunity and available leasable space.

3640 S Noland Rd, Independence, MO 64055

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Explore Off-Market Properties in Independence, MO

Consider similar Off-Market properties in Independence, MO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

9414 Truman Rd

Churches & religious facilities • 2,300 SF

Value Estimation by Request

9414 Truman Rd, Independence, MO 64052

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11413-11417 23Rd St

Individual retail properties

Value Estimation by Request

11413-11417 23Rd St, Independence, MO 64052

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4224 Hocker Ave

Individual retail properties • 10,080 SF

Value Estimation by Request

4224 Hocker Ave, Independence, MO 64055

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301 M 291 Hwy

Office Properties & Spaces • 0.96 Acres

Value Estimation by Request

301 M 291 Hwy, Independence, MO 64056

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19401 Us Highway 40

Office Properties & Spaces • 26,000 SF

Value Estimation by Request

19401 Us Highway 40, Independence, MO 64064

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Independence, MO Office Properties & Spaces Investment Opportunities Market Analysis

Explore 300 office properties & spaces for sale in Independence, MO, showcased through 19 active listings on our real estate platform. These investment opportunities span a total of 6,139,920 square feet of properties for sale, with an estimated market value of $67,516,900.

Prices for office spaces in Independence, MO start at $119,000, averaging $359,132, and reaching up to $2,100,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you have the most current data.

Independence, MO Office Properties & Spaces for Sale

Downtown Independence Commercial Building For Sale

Well-maintained commercial building in Downtown Independence, suitable for various uses.