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    Florence, CO Office Properties & Spaces for Sale

    6 results
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    Historic Downtown Florence Live-Work Space
    $675,000
    0.08 Acres

    Historic Downtown Florence Live-Work Space

    122 W Main St, Florence, CO 81226

    Live-work investment opportunity in historic downtown Florence, Colorado.

    • Live‑work investment opportunity in Historic Downtown Florence.
    • Includes commercial space (previously a wine bar) and a 2‑bedroom residential unit.
    • Prime location on Main Street, close to amenities.
    • Ample free customer parking.
    • Near outdoor recreation: Arkansas River, rafting, hiking, biking, rock climbing.
    Updated: Oct 31, 2025
    View details
    Historic Mixed-Use Building on Main
    $450,000
    0.07 Acres

    Historic Mixed-Use Building on Main

    100 E Main St, Florence, CO 81226

    Charming mixed-use building with retail and residential units.

    • Prime Main Street location in historic Florence, Colorado, offering high visibility and foot traffic.
    • Mixed‑use property with two retail/office storefronts and two updated modern apartments.
    • Excellent income potential from both commercial and residential units.
    • Apartments feature private balconies, blending modern comfort with historic charm.
    • Includes a separate parking lot across the street for residents and employees.
    Updated: Mar 4
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    Historic Mixed-Use Building on Main
    $450,000
    0.07 Acres

    Historic Mixed-Use Building on Main

    Charming historic mixed-use building in Florence, Colorado.

    100 E Main St, Florence, CO 81226
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    Central Florence Office Building
    Contact for pricing
    4,786 SF

    Central Florence Office Building

    Well-maintained office building in central Florence, Colorado.

    521 W 5Th St, Florence, CO 81226
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    Medical Office Building For Sale
    Contact for pricing
    2,800 SF

    Medical Office Building For Sale

    Medical office building with new tenant improvements in central Florence.

    515 W 3Rd St, Florence, CO 81226
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    Versatile Commercial Space in Florence
    Contact for pricing

    Versatile Commercial Space in Florence

    5,600 sq ft commercial space with flexible zoning.

    117 S Petroleum Ave, Florence, CO 81226
    View details
    Based on your search, we've compiled 23 Potential Opportunities for your consideration. Besides 6 Active listings in Florence, CO, we suggest exploring several alternatives: 4 properties in Nearby Cities, and similar 13 Off-Market properties to explore as potential leads

    Explore Opportunities in Nearby Cities

    Here are 4 Similar properties we found in Nearby Locations for your consideration.

    Canon City Commercial Building For Sale
    $1,149,000
    0.68 Acres

    Canon City Commercial Building For Sale

    Two-story commercial building with Highway 50 exposure in Canon City.

    2285 Fremont Dr, Canon City, CO 81212
    View details
    Versatile Commercial Space with Extra Land
    $1,575,000
    2.42 Acres

    Versatile Commercial Space with Extra Land

    39,974 sqft commercial space with retail, office, warehouse potential.

    1630 E Main St, Canon City, CO 81212
    View details
    Pueblo West Warehouse/Grow Opportunity
    $749,000

    Pueblo West Warehouse/Grow Opportunity

    8,400 SF building on 1 acre in Pueblo West.

    157 East Industrial Blvd, Pueblo West, CO 81007
    View details
    Reimagined Office/Warehouse with Highway Frontage
    $2,400,000

    Reimagined Office/Warehouse with Highway Frontage

    State-of-the-art office/warehouse on 2.53 acres with expansion potential.

    315 E Enterprise Dr, Pueblo West, CO 81007
    View details

    Explore Off-Market Properties in Florence, CO

    Consider similar Off-Market properties in Florence, CO. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

    230 Main St

    230 Main St

    OFFICE BUILDING • 1,107 SF
    Value Estimation by Request
    230 Main St, Florence, CO 81226-1424
    View details
    310 Un St

    310 Un St

    MEDICAL BUILDING • 676 SF
    Value Estimation by Request
    310 Un St, Florence, CO 81226-1707
    View details
    515 3rd St

    515 3rd St

    MEDICAL BUILDING • 2,992 SF
    Value Estimation by Request
    515 3rd St, Florence, CO 81226-1115
    View details
    232 Main St

    232 Main St

    OFFICE BUILDING • 1,118 SF
    Value Estimation by Request
    232 Main St, Florence, CO 81226-1531
    View details
    119 Pike Peak Ave

    119 Pike Peak Ave

    OFFICE BUILDING • 6,380 SF
    Value Estimation by Request
    119 Pike Peak Ave, Florence, CO 81226-1430
    View details
    600 3rd St

    600 3rd St

    OFFICE BUILDING • 34,100 SF
    Value Estimation by Request
    600 3rd St, Florence, CO 81226-1143
    View details
    501 5th St

    501 5th St

    MEDICAL BUILDING • 4,598 SF
    Value Estimation by Request
    501 5th St, Florence, CO 81226-1126
    View details
    101 Main St

    101 Main St

    OFFICE BUILDING • 6,433 SF
    Value Estimation by Request
    101 Main St, Florence, CO 81226-1528
    View details
    431 Main St

    431 Main St

    OFFICE BUILDING • 3,217 SF
    Value Estimation by Request
    431 Main St, Florence, CO 81226-1534
    View details
    521 5th St

    521 5th St

    MEDICAL BUILDING • 4,704 SF
    Value Estimation by Request
    521 5th St, Florence, CO 81226-1100
    View details
    218 Main St

    218 Main St

    OFFICE BUILDING • 1,150 SF
    Value Estimation by Request
    218 Main St, Florence, CO 81226-1424
    View details
    700 Shoop Dr

    700 Shoop Dr

    MEDICAL BUILDING • 672 SF
    Value Estimation
    $1,400,000
    700 Shoop Dr, Florence, CO 81226-1111
    View details
    124 Pike Peak Ave

    124 Pike Peak Ave

    OFFICE BUILDING • 5,600 SF
    Value Estimation by Request
    124 Pike Peak Ave, Florence, CO 81226-1431
    View details

    Florence, CO Office Properties & Spaces Investment Opportunities Market Analysis

    Explore 19 office properties & spaces for sale in Florence, CO, showcased through 6 active listings on our real estate platform. These investment opportunities span a total of 799,328 square feet of properties for sale, with an estimated market value of $7,070,000.

    Sale prices for office spaces in Florence, CO start at $130,000, averaging $589,166, and reaching up to $1,400,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

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    Browse Office properties & Spaces for Sale Near Florence, CO

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