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    Anderson, SC Office Properties & Spaces for Lease

    8 results
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    Downtown Anderson Commercial Space Available
    $1,350 / Mo
    2,614 SF

    Downtown Anderson Commercial Space Available

    122 W Whitner St, Anderson, SC 29624

    Versatile 1,300 SF space in historic downtown Anderson.

    • Prime location in historic downtown Anderson, across from the Anderson County Courthouse.
    • Versatile 1,300 square‑foot upper‑level space suitable for office, retail, or studio.
    • Adjacent to the City Parking Garage with ample street parking available.
    • Wood flooring throughout.
    • Adaptable floor plan.
    Updated: Jan 15
    View details
    Class A Office Space
    $3,400 / Mo

    Class A Office Space

    2315 N Main St, Anderson, SC 29621

    Professional office suite for rent in Anderson, SC.

    • Prime Main Street location ideal for high‑visibility professional business.
    • Class A office building with included maintenance, electric, and water.
    • Versatile 2,800 sq ft suite suitable for medical or professional use.
    • Functional layout with five private offices, open floor plan, two restrooms, and a kitchen area.
    • Includes a welcoming reception area and large parking space.
    Updated: Dec 9, 2025
    View details
    Oak Point Plaza Executive Suites
    $20 SF/Yr
    57,107 SF

    Oak Point Plaza Executive Suites

    Anderson, SC Office Space Available

    4120-4126 Clemson Blvd, Anderson, SC 29621
    View details
    Downtown Anderson Retail Space
    $10 SF/Yr
    5,300 SF

    Downtown Anderson Retail Space

    Iconic 5,300 sqft space, prime location.

    110 Greenville St, Anderson, SC 29621
    View details
    Prime Anderson Office Space
    $25 SF/Yr
    1,212 SF

    Prime Anderson Office Space

    1,800 sq ft Office in High-Traffic Area

    1107 Fant St, Anderson, SC 29621
    View details
    Office Space on Hwy 81
    $15 SF/Yr
    2,683 SF

    Office Space on Hwy 81

    Office space for lease near downtown Anderson and Anderson University.

    1704 E Greenville St, Anderson, SC 29621
    View details
    Office Space with Recent Upgrades
    Contact for pricing
    4,200 SF

    Office Space with Recent Upgrades

    Office space featuring new exterior paint and resurfaced parking lot.

    120 E West Pkwy, Anderson, SC 29621
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    Professional Office Space Available
    Contact for pricing
    3,000 SF

    Professional Office Space Available

    Well-maintained office park near US 178/N. Main St.

    341 E Beltline Blvd, Anderson, SC 29621
    View details
    Based on your search, we've compiled 25 Potential Opportunities for your consideration. Besides 8 Active listings in Anderson, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 13 Properties for Sales.

    Explore Office Properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office Space Near Clemson
    $4,000 / Mo
    26,136 SF

    Office Space Near Clemson

    Two-level office building suitable for various businesses, near Clemson.

    865 Old Clemson Hwy, Seneca, SC 29678
    View details
    Seneca Office Space For Lease
    $1,500 / Mo
    26,136 SF

    Seneca Office Space For Lease

    Two-level office building suitable for various businesses, near Clemson.

    865 Old Clemson Hwy, Seneca, SC 29678
    View details
    Downtown Hartwell Office Space
    $16 SF/Yr
    4,800 SF

    Downtown Hartwell Office Space

    Prime renovated office suites, 1200-4800 sqft

    34 Depot St, Hartwell, GA 30643
    View details
    Renovated Commercial Building with Drive-Thru
    $3,850 / Mo
    3,063 SF

    Renovated Commercial Building with Drive-Thru

    Versatile commercial building with drive-thru, ideal for various uses.

    18 W Gibson St, Hartwell, GA 30643
    View details

    Explore Similar Spaces for Sale in Anderson, SC

    Consider Similar Space for Sale. We found 13 Spaces in Nearby Locations matching your search parameters.

    Versatile Mixed-Use Commercial Property
    $750,000
    0.48 Acres

    Versatile Mixed-Use Commercial Property

    Over 5,000 sq ft commercial property with residential area.

    4327 Old Mill Rd, Anderson, SC 29623
    View details
    Move-In Ready Office Suite
    $190,000

    Move-In Ready Office Suite

    Professional office suite near hospital with high traffic and signage.

    400 N Fant St, Anderson, SC 29621
    View details
    Anderson Automotive Garage with Living Space
    $485,000
    4,290 SF

    Anderson Automotive Garage with Living Space

    Automotive garage with living space in thriving Anderson, South Carolina.

    609 Fair St, Anderson, SC 29625
    View details
    Office Space in Anderson, SC
    Contact for pricing
    1.00 Acre

    Office Space in Anderson, SC

    Office property for sale in Anderson, South Carolina.

    2315 N Main St, Anderson, SC 29621
    View details
    Road Frontage Office Space
    $200,000

    Road Frontage Office Space

    Office space with road frontage on a well-traveled bypass.

    805 Highway 28 Byp, Anderson, SC 29624
    View details
    Prime Anderson Commercial Corner Property
    $2,350,000

    Prime Anderson Commercial Corner Property

    Multi-tenant property on 1.21 acres in Anderson's commercial hub.

    110 E Greenville St, Anderson, SC 29621
    View details
    Versatile Mixed-Use Property with Residence
    $750,000

    Versatile Mixed-Use Property with Residence

    Three-level commercial property with residential area and office space.

    4327 Old Mill Rd, Anderson, SC 29621
    View details
    Modernized Income-Generating Commercial Property
    $849,000

    Modernized Income-Generating Commercial Property

    9,500 sq ft building, fully leased, high-traffic location.

    516 Pearman Dairy Rd, Anderson, SC 29625
    View details
    Prime Anderson Office Building
    $925,000
    4,300 SF

    Prime Anderson Office Building

    4,300 SF Office, High Traffic Area

    1502 Greenville St, Anderson, SC 29621
    View details
    Prime Anderson Office Building
    $1,400,000
    3,653 SF

    Prime Anderson Office Building

    Class A Office, 3653 SF, Vacant

    602 Main St, Anderson, SC 29621
    View details
    Prime Anderson Office Land
    $585,000
    14.49 Acres

    Prime Anderson Office Land

    14 Acres, Highway Frontage, SC

    3405 Beckman Dr, Anderson, SC 29624
    View details
    Prime Anderson Office Building
    $900,000
    3,764 SF

    Prime Anderson Office Building

    3,764 SF Office Space - Vacant

    3115 Martin Luther King Jr Blvd, Anderson, SC 29625
    View details
    Prime Anderson Office Complex
    $4,000,000
    49.30 Acres

    Prime Anderson Office Complex

    Spacious office building on large lot

    330 Masters Blvd, Anderson, SC 29626
    View details

    Anderson, SC Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Anderson, SC with 21 listings featured on our commercial real estate exchange. The current inventory includes 3,184,915,540 square feet of properties with an estimated lease value of $91 SF/Yr.

    Estimated lease rates for Office Properties & Spaces in Anderson, SC begin at $6 SF/Yr, with an average of $15 SF/Yr and extend to $25 SF/Yr.
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    Popular Searches in Anderson, SC

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    Most Searched ZIP Codes in Anderson, SC

    • 29621
    • 29624
    • 29626
    • 29625

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