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    Tupelo, MS Office Spaces for Lease

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    Office Space in Tupelo
    Updated: Nov 24, 2025
    Office Space in Tupelo

    609 Brunson Dr, Tupelo, MS

    $18 SF/Yr
    3,785 sqft $5,677/Mo
    Office space available for lease
    Located in Tupelo, Mississippi
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    Office Space For Rent
    Updated: Nov 24, 2025
    Office Space For Rent

    499 S Gloster St, Tupelo, MS

    $18 SF/Yr
    2,082 sqft $3,123/Mo
    Office space available for lease
    Located in Tupelo, Mississippi
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    Office Space in Tupelo
    Office Space in Tupelo

    144 S Thomas St, Tupelo, MS

    $16 SF/Yr
    1,140 sqft $1,520/Mo

    Office space available for lease in Tupelo, Mississippi.

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    Office Space in Tupelo
    Office Space in Tupelo

    495 S Gloster St, Tupelo, MS

    $20 SF/Yr
    2,323 sqft $3,871/Mo

    Office space available for lease in Tupelo, Mississippi.

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    Updated Historical Flex Space
    Updated Historical Flex Space

    654 W Main St, Tupelo, MS 38804

    $14 SF/Yr

    Storefront retail or office space near Crosstown in Tupelo.

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    Two-Story Downtown Office Space
    Two-Story Downtown Office Space

    84 Clark Boulevard, Tupelo, MS 38804

    Contact for pricing

    Flexible two-story office layout with multiple private offices and dedicated training and conference rooms.

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    Office Space Available For Rent
    Office Space Available For Rent

    114 S Broadway St, Tupelo, MS

    Contact for pricing
    2,100 sqft

    Office space available for rent, totaling 2,100 square feet.

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    Downtown Tupelo Office Space Available
    Downtown Tupelo Office Space Available

    111 S Spring St, Tupelo, MS 38804

    $16 SF/Yr
    5,525 sqft $7,366/Mo

    Office space for lease in historic downtown Tupelo.

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    Tupelo Office Building Available
    Tupelo Office Building Available

    809 Varsity Dr, Tupelo, MS

    Contact for pricing
    21,499 sqft

    Office building with 21,499 square feet available for lease/sale.

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    Spacious Warehouse with Office Space
    Spacious Warehouse with Office Space

    4799 S Eason Blvd, Tupelo, MS 38801

    Contact for pricing
    320,000 sqft

    320,000 SF warehouse with 14,000 SF office on 41.6 acres.

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    Upscale Office Space Available
    Upscale Office Space Available

    431 W Main St, Tupelo, MS 38804

    $16 SF/Yr

    Professional office building in the heart of the CBD.

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    Professional Office Complex Space Available
    Professional Office Complex Space Available

    144 S Thomas St, Tupelo, MS 38801

    $16 SF/Yr
    18,000 sqft $24,000/Mo

    Modernized office spaces available in a multi-tenant professional complex.

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    Retail Space in Tupelo Center
    Retail Space in Tupelo Center

    3875 N Gloster St, Tupelo, MS 38804

    $30 SF/Yr
    66,000 sqft $165,000/Mo

    Retail spaces available in a busy shopping center.

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    Class A Medical Complex Space
    Class A Medical Complex Space

    961 S Gloster St, Tupelo, MS 38801

    $22 SF/Yr

    Adaptable medical space near North MS Medical Center.

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    Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 14 Active listings in Tupelo, MS, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 7 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Office or Retail Space
    Office or Retail Space

    310 4th Ave, Red Bay, AL 35582

    $1,500/Mo
    1,550 sqft $11 SF/Yr

    Lease a Main Street building with an existing office configuration and shared parking lot with a nearby restaurant.

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    Office or Retail Space
    Office or Retail Space

    310 4th Ave, Red Bay, AL 35582

    $1,500/Mo
    1,550 sqft $11 SF/Yr

    Leased office-configured space in a high-traffic setting with shared parking next to a Sub Way restaurant.

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    North Lamar Commercial Space
    North Lamar Commercial Space

    1009 N Lamar, Oxford, MS 38655

    Contact for pricing
    1,975 sqft

    New construction mixed-use space on North Lamar Corridor.

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    Oxford Flex-Use Commercial Space
    Oxford Flex-Use Commercial Space

    2014 University Ave, Oxford, MS 38655

    $21 SF/Yr

    Two-story commercial space in Oxford, across from Kroger.

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    Similar Spaces for Sale in Tupelo, MS

    Consider Similar Space for Sale. We found 7 Spaces matching your search parameters.

    Office Building with Mixed Use Zoning
    Office Building with Mixed Use Zoning

    Tupelo, MS 38801

    $475,000
    3,225 sqft 0.34 AC lot

    Well-sized office property offered for sale, situated within mixed use zoning for flexible planning.

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    Tupelo Office Building For Sale
    Tupelo Office Building For Sale

    1015 South Green Street, Tupelo, MS 38804

    $3,500,000
    48,056 sqft

    48,056 square foot office building in Tupelo, Mississippi.

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    Industrial Warehouse with Office
    Industrial Warehouse with Office

    2214-a S Green St., Tupelo, MS 38801

    Contact for pricing
    50,000 sqft 4.70 AC lot

    A fully sprinklered warehouse with dock-high loading, 24-foot eaves, and an on-site air-conditioned office.

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    Flex Space with Roll-Up Door
    Flex Space with Roll-Up Door

    613 President Ave., Tupelo, MS 38801

    Contact for pricing
    3,750 sqft

    Front office area with lobby and storage connects to a warehouse with roll-up door and back utilities.

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    Office Space in Tupelo, MS
    Office Space in Tupelo, MS

    1203 Nelle St, Tupelo, MS

    $225,000
    2,400 sqft 0.11 AC lot

    Office property with 2400 square feet available for sale.

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    Office Suite with Central Meeting Room
    Office Suite with Central Meeting Room

    1150-e S Green St., Tupelo, MS 38804

    Contact for pricing

    Large office suite in Tupelo with a central meeting hub, private offices, kitchen, and two restrooms.

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    Built-Out Office Suite with Windows
    Built-Out Office Suite with Windows

    1150-f S Green St., Tupelo, MS 38804

    Contact for pricing

    Architectural office suite features multiple windows, private office layout, and fully sprinklered, air-conditioned interior.

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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Corner Lot on Highway 72
    Corner Lot on Highway 72

    30472 Highway 72, Madison, AL 35756

    $5,000/Mo
    1,875 sqft $32 SF/Yr

    1.7 acre corner lot zoned for commercial, medical, residential.

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    Office Development Land For Lease
    Office Development Land For Lease

    1323 Strawfloor Drive, Jonesboro, AR 72401

    Contact for pricing
    4,000 sqft

    2.43 acres for office development with build-to-suit opportunity.

    View details
    Highway 14 Commercial Investment Property
    Highway 14 Commercial Investment Property

    2400 Highway 14, Millbrook, AL 36054

    $3,980,250 SF/Yr
    770,576 sqft $255,590,427,000/Mo

    Investment property with highway frontage in growing Millbrook corridor.

    View details
    Commercial Land on Hardy Street
    Commercial Land on Hardy Street

    3104 Hardy St, Hattiesburg, MS 39401

    Contact for pricing

    0.66 acres of commercial land in high-traffic location.

    View details

    Tupelo, MS Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Tupelo, MS with 14 listings featured on our commercial real estate exchange. The current inventory includes 127,955 square feet of properties with an estimated lease value of $284 SF/Yr.

    Estimated lease rates for Office Spaces in Tupelo, MS begin at $16 SF/Yr, with an average of $28 SF/Yr and extend to $115 SF/Yr.
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    Most Searched ZIP Codes in Tupelo, MS

    • 38804
    • 38801

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