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Louis, MO Office Spaces for Lease

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East St Louis, IL Sauget, IL Cahokia, IL Madison, IL Washington Park, IL Granite City, IL Maplewood, MO Clayton, MO
189 properties
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Coworking and Private Offices with Flexible Terms at MO, St. Louis - Craigshire Rd. Contact us today to book a tour!
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Coworking and Private Offices with Flexible Terms at Spaces Central West End. Contact us today to book a tour!
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Office Units with Private Offices
Updated: Jun 22
Office Units with Private Offices

Saint Louis, MO 63139

$2,860/Mo
4,260 sqft 0.61 AC lot
Multiple office configurations spanning first- and second‑floor suites
First‑floor layout includes reception, full kitchen, 2 restrooms, 5 private offices, and training room
Second‑floor suite features conference room, 5 private offices, bullpen, and large storage room
Additional open‑plan suite includes 2 restrooms and 1 private room
Abundant parking plus building and pole signage
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Renovated Mixed-Use Commercial Building
Updated: Jun 24
Renovated Mixed-Use Commercial Building

Saint Louis, MO 63111

$400/Mo
0.12 AC lot
6,000 square feet with 12 offices, a conference room, open retail area, kitchen, and 2 handicap‑accessible bathrooms
Renovation and replacement work completed in 2019
Three basements provide additional space outside the stated square footage
20‑space concrete parking lot plus open parking and driveway access
Full‑service lease format includes utilities and use of shared restrooms and kitchen area
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Multi-Level Church Facility
Multi-Level Church Facility

Saint Louis, MO 63113

$4,000/Mo
0.33 AC lot

Flexible commercial space includes office, daycare, kitchen, fellowship, and potential sanctuary leasing options.

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Coworking and Private Offices with Flexible Terms at Deloitte Building. Contact us today to book a tour!
Coworking and Private Offices with Flexible Terms at Deloitte Building. Contact us today to book a tour!

100 4Th St, Unit 550, Saint Louis, MO 63102

16 available spaces from 11 to 2,019 sqft
$129-$11,723/Mo per office

Flexible workspace in Deloitte Building. Book a tour & get info

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Office Units with Restrooms
Office Units with Restrooms

Saint Louis, MO 63147

$400/Mo
0.12 AC lot

Two office spaces offer business-address functionality with on-site parking and access to building amenities.

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Office Unit with Private Offices
Office Unit with Private Offices

Saint Louis, MO 63011

$1,300/Mo
0.02 AC lot

A suburban suite provides a private restroom, accessible entrances, and room for interior reconfiguration.

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Creative Space with Exposed Brick
Creative Space with Exposed Brick

1957 Cherokee Street, St, Louis, MO 63118

$1,650/Mo
0.05 AC lot

An open commercial layout with high ceilings accommodates customizable office, studio, showroom, wellness, or retail concepts.

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Office Suite with Private Offices
Office Suite with Private Offices

1001 Craig Rd, Suite 200, Saint Louis, MO 63146

$13 SF/Yr
8,553 sqft

Well-appointed office suite with multiple private offices, training rooms, and conference rooms available for sublease.

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Renovated Office-Warehouse Flex Space
Renovated Office-Warehouse Flex Space

8600 Manchester Road, St, Louis, MO 63144

$5,000/Mo
0.22 AC lot

Combined office and warehouse areas include updated employee facilities and direct loading access.

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Flexible Professional Office Suite
Flexible Professional Office Suite

2258 Schuetz Road, St, Louis, MO 63146

$3,830/Mo
2.12 AC lot

Configured workspace includes private offices, a kitchenette, meeting space, and an open bullpen for collaborative operations.

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Flex Office Warehouse with Dock Door
Flex Office Warehouse with Dock Door

6108 Baumgartner Xing, Saint Louis, MO 63129

$7,250/Mo
5,000 sqft

5,000+ SF flex building features office space, warehouse area, kitchen area, and two restrooms with both dock-high and drive-in doors.

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Professional Office Suite
Professional Office Suite

2258 Schuetz Road, St, Louis, MO 63146

$4,630/Mo
2.12 AC lot

White-box delivery, central air, and flexible suite sizing support a practical professional office setting.

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Two-Level Office Units
Two-Level Office Units

3018 S Jefferson Avenue, St, Louis, MO 63118

$2,000/Mo
0.07 AC lot

Second- and third-floor space supports office, studio, and retail-oriented uses in Benton Park.

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Temperature-Controlled Office/Warehouse Suite
Temperature-Controlled Office/Warehouse Suite

11040 Lin Valle Dr, Saint Louis, MO 63123

$12 SF/Yr
1,075 sqft

Flex office/warehouse suite includes a private office and temperature-controlled space with an overhead door.

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Retail-Office Space with Highway Exposure
Retail-Office Space with Highway Exposure

12440 Lusher Road, Saint Louis, MO 63138

$12 SF/Yr
6,975 sqft

Retail/office building on major roadways with direct in-front Metro Transit access and strong Highway 367 traffic exposure.

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Office Space with Private Entrance
Office Space with Private Entrance

2117-2121 S Brentwood Blvd, Saint Louis, MO 63144

$20 SF/Yr
3,418 sqft

Two-level office suite offers private entrance, multiple offices, and built-in kitchen and breakroom areas.

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First-Floor Office Suite
First-Floor Office Suite

121 Hunter Ave, Saint Louis, MO 63124

$22 SF/Yr
1,540 sqft

Five private offices and a conference room create a practical multi-room professional workspace.

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Professional Office Suite
Professional Office Suite

201-2258 Schuetz Rd, Saint Louis, MO 63146

$3,830/Mo
2,702 sqft

Office suite includes four private offices, a kitchenette, and a conference/training room with open bullpen area.

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Class A Office Space
Class A Office Space

Saint Louis, MO 63102

$215 SF/Yr
348,675 sqft

Contiguous leasing options support a range of tenant sizes within a downtown office tower.

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White-Box Office Suite
White-Box Office Suite

205-2258 Schuetz Rd, Saint Louis, MO 63146

$4,630/Mo
3,268 sqft

Flexible professional office suite available in the 1,500 to 3,268 SF range with a 4.2/1,000 parking ratio.

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Prime St. Louis Commercial Space
Prime St. Louis Commercial Space

Saint Louis, MO 63102

$1,250/Mo
2,802 sqft

Versatile space suitable for retail, creative space, or restaurant use.

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Class A Office/Flex Space
Class A Office/Flex Space

Saint Louis, MO 63114

$10 SF/Yr
4,823 sqft

Office/flex building with contiguous space and highway visibility available for lease.

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Serviced Offices with Business Support at MO, St. Louis - Cedar Plaza. Contact us today to book a tour!
Serviced Offices with Business Support at MO, St. Louis - Cedar Plaza. Contact us today to book a tour!

5000 Cedar Plz St, Louis, MO 63128

16 available spaces from 11 to 1,973 sqft
$129-$15,680/Mo per office

Flexible workspace in MO, St. Louis - Cedar Plaza. Book a tour & get info

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Smart Workspace Options at MO, St. Louis - The Luxe on Lami. Contact us today to book a tour!
Smart Workspace Options at MO, St. Louis - The Luxe on Lami. Contact us today to book a tour!

1031 Lami St 63104 St, Louis, MO 63104

15 available spaces from 11 to 1,646 sqft
$129-$11,961/Mo per office

Flexible workspace in MO, St. Louis - The Luxe on Lami. Book a tour & get info

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Louis, MO Office Spaces Lease Rates & Market Statistics

Explore 189 Office Spaces for lease in Louis, MO on Realmo, a commercial real estate exchange covering the Louis area. The current inventory totals 3,483,258 square feet of properties — an average of ~18,450 SF per listing.

Asking lease rates for Office Spaces in Louis start at $8.06 SF/Yr, average $24.17 SF/Yr, and reach $215 SF/Yr at the top of the market. That's a 27x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $24.17 SF/Yr is 5% below the Missouri state average of $25.39 SF/Yr.

By space type, the market includes 143 office units, 32 office buildings and 22 medical office space listings — medical office space options typically offer the lowest entry point, while office buildings command the highest rates.

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