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    Hampshire County, MA Office Spaces for Lease

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    117 properties
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    Second-Floor Office Suite
    Updated: Jun 11
    Second-Floor Office Suite

    304 Pleasant St, Northampton, MA 01060

    $16 SF/Yr
    3,600 sqft
    Vacant 3,600 SF second‑level office suite with full‑floor, single‑tenant occupancy
    Located at 300 Pleasant Street in Northampton, MA 01060
    Flexible layout suitable for professional, administrative, medical, or office uses
    Lease rate is $4,800 per month plus utilities ($16/SF annually)
    Immediate availability for occupancy
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    Remodeled Retail Space
    Updated: Aug 6
    Remodeled Retail Space

    318 Newton St Unit 1, South Hadley, MA 01075

    $700/Mo
    500 sqft
    Recently remodeled retail space with contemporary interior finishes
    Office or retail configuration supports a range of commercial uses
    Unit 1 can be combined with Unit 2 for an additional 500 SF
    Across from a local high school on a heavily trafficked street
    Located at 318 Newton Street in South Hadley, MA 01075
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    Office Unit with Open Bullpen
    Office Unit with Open Bullpen

    48 N Pleasant St Unit 301, Amherst, MA 01002

    $5,770/Mo
    2,473 sqft

    Accessible office suite with utilities included, private offices, collaborative workspace, and optional furnishings.

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    Contemporary Office Unit
    Contemporary Office Unit

    318 Newton St Unit 2, South Hadley, MA 01075

    $700/Mo
    500 sqft

    Updated interior with flexible office or service-oriented layout opposite a local high school.

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    Turnkey Office Space
    Turnkey Office Space

    32 Industrial Dr E, Northampton, MA 01060

    $17 SF/Yr
    7,000 sqft

    Turnkey second-floor office space with shared conference rooms, kitchen/break room, and ample parking included.

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    Ground-Floor Retail Suite
    Ground-Floor Retail Suite

    422 Main St, Easthampton, MA 01027

    $2,700/Mo
    1,100 sqft

    Flexible suite with storefront windows, a private restroom, and drive-through capability subject to Town approval.

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    Office Unit with Private Entrance
    Office Unit with Private Entrance

    241 King St, #234/236, Northampton, MA 01060

    $1,975/Mo
    900 sqft

    Second-floor suite offers private offices, conference space, a waiting area, and a dedicated restroom.

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    Medical Office Suites with Parking
    Medical Office Suites with Parking

    264 Elm Street, Unit B&C, Northampton, MA 01060

    $22 SF/Yr
    1,285 sqft

    First- and second-floor medical office space with ADA access and over 40 parking spaces.

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    Accessible Office Unit
    Accessible Office Unit

    101-10-123 Union St, Easthampton, MA 01027

    $450/Mo
    145 sqft

    Lease includes utilities, Wi-Fi, parking, and use of shared conference and kitchenette areas.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    15 Oneil St, 2nd Floor Right, Easthampton, MA 01027

    $750/Mo
    1,000 sqft

    Brand-new second-floor office space features mini-split HVAC and a half bath.

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    Downtown Office Suite
    Downtown Office Suite

    48 N Pleasant Street # 301, Amherst, MA 01002

    $5,770/Mo
    2,473 sqft

    Office suite with reception, private offices, conference room, kitchenette, and open bullpen; utilities included.

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    Medical Office Space with Exam Rooms
    Medical Office Space with Exam Rooms

    264 Elm St B&c, Northampton, MA 01060

    $22 SF/Yr
    1,285 sqft

    Flexible first- and second-floor suites include reception areas, private offices, exam rooms, and ADA-accessible access.

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    Retail/Office Suite
    Retail/Office Suite

    131 Main St # 106-107, Hatfield, MA 01038

    $1,400/Mo
    1,000 sqft

    Flexible 1,000 SF suite available March 1, 2026 with on-site parking at 131 Main St.

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    First-Floor Office Condo Suite
    First-Floor Office Condo Suite

    228 Triangle Street # 2, Amherst, MA 01002

    $1,100/Mo
    500 sqft

    First-floor office condo with an open layout, private restroom, and off-street parking.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    234236-241 King St, Northampton, MA 01060

    $1,975/Mo
    900 sqft

    Second-floor suite with three private offices, conference room, waiting area, and private restroom for office tenants.

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    First-Floor Office Unit
    First-Floor Office Unit

    30 Boltwood Walk # 2, Amherst, MA 01002

    $600/Mo
    145 sqft

    Office suite with shared business amenities and accessible restroom facilities.

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    Affordable Office Space For Rent
    Affordable Office Space For Rent

    518 Pleasant St 12, Northampton, MA 01060

    $500/Mo
    550 sqft

    Third-floor commercial space near Main St with utilities included.

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    Florence Office Space For Rent
    Florence Office Space For Rent

    41 Main St, #B2, Northampton, MA 01062

    $750/Mo
    900 sqft

    900 SF office space in central Florence.

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    Charming Office Space in Northampton
    Charming Office Space in Northampton

    46 Main St Front, Northampton, MA 01060

    $650/Mo
    419 sqft

    Unique office space with exposed brick, high ceilings, and natural light.

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    Lower Level Office Suite
    Lower Level Office Suite

    B2-41 Main St, Northampton, MA

    $750/Mo
    900 sqft

    Lower level suite with three private offices and open workspace, zoned General Business.

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    First-Floor Private Office Suite
    First-Floor Private Office Suite

    17 New South, #201, Northampton, MA 01060

    $1,000/Mo
    180 sqft

    First-floor office suite with private street entrance, built-in bookcases, shared waiting area and restroom, plus reserved off-street parking.

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    Second-Floor Office Suite
    Second-Floor Office Suite

    2c-7 N Pleasant St, Amherst, MA 01002

    $2,700/Mo
    1,050 sqft

    Second-floor office suite with a front lobby, waiting/reception area, and four private offices in an accessible building.

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    Renovated Office Suite with Kitchenette
    Renovated Office Suite with Kitchenette

    B1-41 Main St, Northampton, MA

    $1,500/Mo
    1,300 sqft

    Lower-level office suite offers four private offices, conference space, open workspace, and a kitchenette.

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    Remodeled Office Unit
    Remodeled Office Unit

    1-318 Newton St, South Hadley, MA 01075

    $700/Mo
    500 sqft

    Contemporary commercial space supports professional office and retail service operations.

    View details

    Hampshire County, MA Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Hampshire County, MA with 117 listings featured on our commercial real estate exchange. The current inventory includes 175,481 square feet of properties with an estimated lease value of $2,029.

    Estimated lease rates for Office Spaces in Hampshire County, MA begin at $9 SF/Yr, with an average of $28.59 SF/Yr and extend to $210 SF/Yr.
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