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Marathon, FL Office Spaces for Lease

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Islamorada, FL Plantation Key, FL Big Pine Key, FL
11 properties
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Combined Office Units with Flexible Layout
Updated: Jul 30
Combined Office Units with Flexible Layout

10095 Overseas Highway, Marathon, FL 33050

$4,456/Mo
2,139 sqft
Combined units 10005 and 10015 provide approximately 2,139 square feet
Expected availability beginning January 1, 2027
Potential future division into two suites of approximately 1,069 square feet each
Current occupant is the Monroe County Supervisor of Elections
Located at 10095 Overseas Highway, Marathon, FL 33050
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Combined Professional Office Units
Updated: Jul 30
Combined Professional Office Units

10095 Overseas Highway, Marathon, FL 33050

$2,228/Mo
1,069 sqft
Two office units currently configured as one combined suite
Expected availability beginning January 1, 2027
Current occupancy by the Monroe County Supervisor of Elections
Located along the Overseas Highway corridor in Marathon
Office layout identified for professional, administrative, medical, governmental, or general office use
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Professional Office Suite
Professional Office Suite

10095 Overseas Highway, Marathon, FL 33050

$2,228/Mo
1,069 sqft

Office space in a maintained commercial building along the Overseas Highway corridor, with potential for professional and administrative uses.

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Combined Professional Office Units
Combined Professional Office Units

10055-10095 Overseas Hwy, Marathon, FL 33050

$2,228/Mo
2,139 sqft

Two adjacent units currently function together, with future division into separate office spaces under consideration.

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Medical Office Suite with Highway Frontage
Medical Office Suite with Highway Frontage

2357 Overseas Highway, Marathon, FL 33050

$7,000/Mo
4,188 sqft 0.11 AC lot

Move-in ready medical office suite with highway frontage and two entrances in Marathon, FL.

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Key Vaca Center: Marathon Office Space
Key Vaca Center: Marathon Office Space

10045 Overseas Hwy, Marathon, FL 33050

$7.20 SF/Yr
10,288 sqft

14,000 SF Office Building, Multiple Suites Available

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Professional Office Units
Professional Office Units

5701 Overseas Hwy, Marathon, FL 33050

Contact for pricing
4,139 sqft

Professional center includes medical, legal, service, retail, and social-service occupants.

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Top-Floor Office Suite with Private Bath
Top-Floor Office Suite with Private Bath

216217-11400 Overseas Hwy, Marathon, FL 33050

$2,300/Mo

Top-floor office suite in a managed commercial plaza with private bath, elevator access, and ample client parking.

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Shared Office Space with Natural Lighting
Shared Office Space with Natural Lighting

9141 Overseas Hwy, Marathon, FL 33050

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83 sqft

Shared office space in the Marathon Berkshire Business Center with electric and water included.

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KEY VACA CENTER
KEY VACA CENTER

10095 Overseas Hwy, Marathon, FL 33050

Contact for pricing
10,288 sqft

Office / Retail / Medical Offices - 3 spaces available | 1,000 SqFt - 4,020 SqFt

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Key Vaca Center: Marathon Office Space
Key Vaca Center: Marathon Office Space

10045 Overseas Hwy, Marathon, FL 33050

$7.20 SF/Yr
10,288 sqft

14,000 SF Office Building, Multiple Suites Available

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Based on your search, we've compiled 27 Potential Opportunities for your consideration. Besides 11 Active listings in Marathon, FL, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 12 Properties for Sales.

Office Spaces for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Highway-Fronted Mixed-Use Property
Highway-Fronted Mixed-Use Property

1-88100 Overseas Hwy, Islamorada, FL 33036

$3,200/Mo

Flexible space combines residential features with room for business use and outdoor activity.

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Open Warehouse Flex Space
Open Warehouse Flex Space

210 Morada Way, Islamorada, FL 33036

Contact for pricing
10,000 sqft

Open warehouse-style space with five oversized loading doors, two offices, and modern multi-stall bathrooms.

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Elevator-Served Office Unit
Elevator-Served Office Unit

21460 Overseas Highway, Cudjoe Key, FL 33042

$2,100/Mo
862 sqft 0.75 AC lot

Private-restroom office suite in a concrete, elevator-served building with off-street parking.

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Elevator-Served Office Unit
Elevator-Served Office Unit

21460 Overseas Highway, Cudjoe Key, FL 33042

$800/Mo
750 sqft 0.75 AC lot

Three-story concrete building provides off-street parking and direct access to US Hwy 1.

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Similar Spaces for Sale in Marathon, FL

Consider Similar Space for Sale. We found 12 Spaces matching your search parameters.

Mixed-Use Building with Drive-Through
Mixed-Use Building with Drive-Through

11401 Overseas Highway, Marathon, FL 33050

$1,533,333
3,429 sqft 0.34 AC lot

MU - Mixed Use Commercial zoning supports office and retail use potential.

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Contiguous Medical Office Suites
Contiguous Medical Office Suites

5701 Overseas Hwy 10, Marathon, FL 33050

$725,000
2,556 sqft

Three contiguous office units offer flexible medical or professional office configurations within a prominent highway retail corridor.

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Office Unit with Highway Frontage
Office Unit with Highway Frontage

5701 Overseas Highway Unit 1, Marathon, FL 33050

$395,000
1,128 sqft

Professional office unit with multiple private offices, a reception area, kitchen, half bath, and central air.

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Waterfront Mixed-Use Property
Waterfront Mixed-Use Property

14 125Th Street Gulf, Marathon, FL 33050

$3,549,000
6,128 sqft 1.57 AC lot

MU - Mixed Use Commercial zoning accompanies a raised concrete building and waterfront redevelopment site.

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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

2901 Overseas Highway, Marathon, FL 33050

Contact for pricing
4,560 sqft 0.35 AC lot

Flexible commercial suites occupy the lower level, with two residential apartments above and a rear parcel with canal access.

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Shared Office Coworking Space
Shared Office Coworking Space

9141 Overseas Highway, Marathon, FL 33050

Contact for pricing
84 sqft 0.47 AC lot

Professional workspace within a mixed-use commercial property with shared break-room and restroom facilities.

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Mixed-Use Retail and Apartments
Mixed-Use Retail and Apartments

6799 Overseas Hwy, Marathon, FL 33050

Contact for pricing
4,858 sqft 0.24 AC lot

Two-story concrete building with three retail/office units on the ground floor and three residential apartments above.

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Updated Medical Office Suite
Updated Medical Office Suite

5-5701 Overseas Hwy, Marathon, FL 33050

$265,000

Updated office suite with a front desk, waiting room, three separate rooms, and one full bathroom.

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Storefront Building with Pylon Sign
Storefront Building with Pylon Sign

2315 Overseas Highway, Marathon, FL 33050

Contact for pricing
2,360 sqft

CBS construction, central air conditioning, and parking support retail or office occupancy.

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Corner Mixed-Use Land with Office
Corner Mixed-Use Land with Office

4000 Overseas Highway, Marathon, FL 33050

Contact for pricing
850 sqft 0.87 AC lot

Elevated corner property with 200 feet of Overseas Highway frontage, enclosed with CBS retaining walls, plus an 850 sq. ft. office.

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Waterfront Mixed-Use Property
Waterfront Mixed-Use Property

11215 Overseas Highway, Marathon, FL 33050

Contact for pricing

Mixed-use waterfront property with marina authorization, dockage, commercial space, and a furnished residential component.

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Established Business in Florida Keys
Established Business in Florida Keys

Montage FL Keys Souvenirs, Marathon, FL 33050

$99,000

Work and live in paradise with this established business.

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Marathon, FL Office Spaces Lease Rates & Market Statistics

Explore 11 Office Spaces for lease in Marathon, FL on Realmo, a commercial real estate exchange covering the Marathon area. The current inventory totals 45,690 square feet of properties — an average of ~4,150 SF per listing.

Asking lease rates for Office Spaces in Marathon start at $7.20 SF/Yr, average $17.43 SF/Yr, and reach $25.01 SF/Yr at the top of the market. That's a 3x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. At $17.43 SF/Yr, the local average runs 50% below Florida's state average of $35.15 SF/Yr.

Marathon accounts for 22% of the 50 office spaces currently available across Monroe County, where nearby markets include Key West and Key Largo. By space type, the market includes 7 office units and 3 other office properties — other office properties typically offer the lowest entry point, while office units command the highest rates.

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