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    Lewes, DE Office Properties & Spaces for Lease

    11 results
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    New
    Lewes Office/Flex Space Available
    $22 SF/Yr

    Lewes Office/Flex Space Available

    32191 Nassau Rd,Unit 2, Lewes, DE 19958

    Professional office/flex space in Lewes, DE, ideal for various businesses.

    • Versatile space suitable for various professional uses (design, consulting, architectural, engineering, fitness).
    • Convenient location adjacent to the Lewes‑Georgetown Bike Path.
    • Ample parking available.
    • Potential lease incentives to offset impact of nearby road construction.
    • Open floor plan with two private offices and a kitchenette.
    Last Update: Dec 9
    View details
    New
    Prime Medical/Executive Office Space
    $23 SF/Yr
    46,609 SF

    Prime Medical/Executive Office Space

    16529 N Coastal Hwy,Unit 4720, Lewes, DE 19958

    Versatile office space ideal for medical or professional use.

    • Prime professional space ideal for medical, executive, or professional office use.
    • Features a versatile layout with multiple private offices/exam rooms and flexible workspaces.
    • Excellent front‑facing visibility and convenient client access.
    • Strategically positioned near major healthcare destinations.
    • Three potential reception areas offer flexible options.
    Last Update: Dec 9
    View details
    New
    Lewes Office Space For Lease
    $23 SF/Yr
    46,609 SF

    Lewes Office Space For Lease

    Prime medical or executive office space in Lewes, Delaware.
    16529 N Coastal Hwy, Lewes, DE 19958
    View details
    New
    Lewes, DE Office Space
    $23 SF/Yr
    46,609 SF

    Lewes, DE Office Space

    Prime medical or executive office space for lease in Lewes.
    16529 N Coastal Hwy, Lewes, DE 19958
    View details
    Lewes Office Space For Lease
    $6,000 /Mo
    21,344 SF

    Lewes Office Space For Lease

    3,200 SF office building in desirable Nassau Commons location.
    17503 Nassau Cmns Blvd, Lewes, DE 19958
    View details
    Spacious Commercial Space in Lewes
    $4,000 /Mo
    21,344 SF

    Spacious Commercial Space in Lewes

    Large commercial space with parking and flexible usage options available.
    17569 Nassau Cmns Blvd, Lewes, DE 19958
    View details
    Lewes Office Suites For Lease
    $650 /Mo

    Lewes Office Suites For Lease

    Single-room office suites available in Lewes, Delaware, with utilities included.
    17527 Nassau Cmns Blvd, Lewes, DE 19958
    View details
    Route 1 Commercial Space Available
    $3,000 /Mo

    Route 1 Commercial Space Available

    Prime commercial space on Route 1, available immediately.
    18354 Coastal Hwy, Lewes, DE 19958
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    Lewes Office Building on Highway
    $25 SF/Yr
    6,340 SF

    Lewes Office Building on Highway

    Professional office building with direct highway frontage in Lewes, DE.
    18344 Coastal Hwy, Lewes, DE 19958
    View details
    Office Space in Nassau Commons
    $1,500 /Mo

    Office Space in Nassau Commons

    Office space available for lease starting October 1, 2025.
    17577 Nassau Commons Blvd, Lewes, DE 19958
    View details
    New Retail/Office Pad Sites
    $30 SF/Yr

    New Retail/Office Pad Sites

    Two new construction pad sites in a vibrant community.
    Zinfandel Ln, Lewes, DE 19958
    View details
    Based on your search, we've compiled 20 Potential Opportunities for your consideration. Besides 11 Active listings in Lewes, DE, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Explore Office Properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    New
    Medical Arts Building Office Suites
    $1,400 /Mo

    Medical Arts Building Office Suites

    Medical office suites for lease near Beebe Hospital.
    18947 John J. Williams Hwy, Rehoboth Beach, DE 19971
    View details
    Grotto Corporate Center Office Space
    $30 SF/Yr

    Grotto Corporate Center Office Space

    Ground floor office units for lease in Rehoboth Beach.
    20376 Coastal Hwy, Rehoboth Beach, DE 19971
    View details
    Prime Milton Medical Office Space
    $22 SF/Yr
    4,200 SF

    Prime Milton Medical Office Space

    4,200 SF Medical Office - Available Now
    616 Mulberry St, Milton, DE 19968
    View details
    Prime Commercial Space For Rent
    $18 SF/Yr

    Prime Commercial Space For Rent

    4,200 SF commercial space ideal for office, retail, or medical.
    612 Mulberry St, Milton, DE 19968
    View details

    Explore Similar Spaces for Sale in Lewes, DE

    Consider Similar Space for Sale. We found 5 Spaces in Nearby Locations matching your search parameters.

    Lewes Office Building on Coastal Highway
    Contact for pricing
    6,340 SF

    Lewes Office Building on Coastal Highway

    Professional office building with highway frontage and high visibility.
    18334 Coastal Hwy, Lewes, DE 19958
    View details
    Lewes Office Building - Investment Opportunity
    $1,400,000
    2,600 SF

    Lewes Office Building - Investment Opportunity

    Prime Lewes location, 2600 sq ft office, 0.49 acre lot.
    17493 Nassau Cmns Blvd, Lewes, DE 19958
    View details
    Lewes Office Building - High ROI
    $2,200,000
    3,200 SF

    Lewes Office Building - High ROI

    Prime Lewes location, high rental income, recent upgrades.
    1546 Savannah Rd, Lewes, DE 19958
    View details
    Coastal Highway Office Space Available
    Contact for pricing
    1.64 Acres

    Coastal Highway Office Space Available

    New Lewes Office, High Traffic Area
    18422 Coastal Hwy, Lewes, DE 19958
    View details
    Lewes Office Space: Prime Location
    $499,000
    900 SF

    Lewes Office Space: Prime Location

    Beachfront Office, Income Producing, Updated
    110 Anglers Rd, Lewes, DE 19958
    View details

    Lewes, DE Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Lewes, DE with 16 listings featured on our commercial real estate exchange. The current inventory includes 8,226,584,716 square feet of properties with an estimated lease value of $10,094 /Mo.

    Estimated lease rates for Office Properties & Spaces in Lewes, DE begin at $23 SF/Yr, with an average of $1,682 /Mo and extend to $6,000 /Mo.
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    Browse Office Properties & Spaces for Lease Near Lewes, DE

    Popular Searches in Lewes, DE

    Most Searched ZIP Codes in Lewes, DE

    • 19958

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