Add Listing
    For Lease
    • For Sale
    • For Lease
    • Recently Sold
    • Property Lookup
    • Brokers
    Office
    1
    • Retail
    • Restaurant
    • Office
    • Coworking
    • Medical Space
    • Automotive
    • Industrial
    • Warehouse
    • Flex
    • Hospitality
    • Sports & Entertainment
    • Specialty
    Price
    Price range
    $
    $
    Size
    Property size / sq.ft.
    AI Search

    Meet Realmo: The Largest Hub
    of Commercial Real     Estate in the US

    Over 1 million active listings and over 150 million property profiles

    Lewes, DE Office Properties & Spaces for Lease

    List
    Map
    Wilmington, DE Newark, DE New Castle, DE
    6 results
    Versatile Lewes Office Space
    $23 SF/Yr

    Versatile Lewes Office Space

    16529 N COASTAL Highway, Lewes, DE 19958

    Professional office space ideal for medical or executive use.

    • Versatile layout ideal for medical, executive, or professional office use, featuring multiple private offices/exam rooms and flexible workspaces.
    • Excellent front‑facing visibility and convenient client access.
    • Strategically positioned near major healthcare destinations.
    • Opportunity to customize the layout based on operational needs.
    • Two potential reception areas at the main front entrance and a large lobby.
    Updated: Feb 23
    View details
    Lewes Office/Flex Space Available
    $20 SF/Yr

    Lewes Office/Flex Space Available

    32191 NASSAU Road, Lewes, DE 19958

    Professional office/flex space in Lewes, DE, ideal for various uses.

    • Flexible space suitable for a variety of professional uses.
    • Convenient location adjacent to the Lewes‑Georgetown Bike Path and near established businesses.
    • Ample parking available.
    • Lease incentives offered to offset the impact of nearby road construction.
    • Open floor plan with two private offices, kitchenette, and built‑in nooks.
    Updated: May 20, 2025
    View details
    Single-Room Office Suite in Lewes
    $575 /Mo

    Single-Room Office Suite in Lewes

    Second-floor office suite with shared amenities, utilities included.

    17527 NASSAU COMMONS Boulevard, Lewes, DE 19958
    View details
    New Retail/Office Pad Sites
    $30 SF/Yr

    New Retail/Office Pad Sites

    Two new construction pad sites in a vibrant community.

    Zinfandel Lane, Lewes, DE 19958
    View details
    Coastal Highway Commercial Opportunity
    Contact for pricing

    Coastal Highway Commercial Opportunity

    Prime commercial parcel on Coastal Highway, available February 2026.

    18355 Coastal Hwy, Lewes, DE 19958
    View details
    Lewes Office Building on Highway
    $25 SF/Yr
    6,340 SF

    Lewes Office Building on Highway

    Professional office building with direct highway frontage in Lewes, DE.

    18344 Coastal Hwy, Lewes, DE
    View details
    Based on your search, we've compiled 19 Potential Opportunities for your consideration. Besides 6 Active listings in Lewes, DE, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 5 Properties for Sales.

    Explore Office properties & Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Versatile Retail/Office/Flex Space Available
    $12 SF/Yr
    2,925 SF

    Versatile Retail/Office/Flex Space Available

    2,925 sqft retail/office/flex space in Laurel, DE for lease.

    10771 LAUREL PLAZA ROAD, Laurel, DE 19956
    View details
    CommercialLease - LAUREL, DE
    $2,680 /Mo

    CommercialLease - LAUREL, DE

    Flex space

    10771 LAUREL PLAZA ROAD, Laurel, DE 19956
    View details
    Medical Office Space on Route 1
    $24 SF/Yr
    1,500 SF

    Medical Office Space on Route 1

    Medical office spaces available in Milford, DE, on Route 1.

    100 Silicato Pkwy, Milford, DE 19963
    View details
    Medical/Office Space Available for Rent
    $24 SF/Yr
    1,350 SF

    Medical/Office Space Available for Rent

    1350 SF medical/office space available for rent.

    100 Silicato Pkwy, Milford, DE
    View details

    Explore Similar Spaces for Sale in Lewes, DE

    Consider Similar Space for Sale. We found 5 Spaces matching your search parameters.

    Commercial Property with Residential Structure
    $975,000
    0.51 Acres

    Commercial Property with Residential Structure

    Half-acre commercial property with existing home and business potential.

    17548 SHADY ROAD, Lewes, DE 19958
    View details
    Versatile Commercial Space For Sale
    Contact for pricing
    1,962 SF

    Versatile Commercial Space For Sale

    Adaptable 1,962 SF commercial space, ideal for various businesses.

    32191 Nassau Road, Lewes, DE 19958
    View details
    Lewes Office Building on Coastal Highway
    Contact for pricing
    6,340 SF

    Lewes Office Building on Coastal Highway

    Professional office building with highway frontage and high visibility.

    18334 Coastal Highway, Lewes, DE 19958
    View details
    Office/Flex Space For Sale
    Contact for pricing

    Office/Flex Space For Sale

    Professional office/flex space ideal for design, consulting, or fitness.

    32191 Nassau Road 2, Lewes, DE 19958
    View details
    Commercial Pad Sites For Sale
    Contact for pricing

    Commercial Pad Sites For Sale

    Two pad sites suitable for retail, restaurant, office, or medical.

    Zinfandel Lane, Lewes, DE 19958
    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land in Summit City
    $2,300 /Mo

    Commercial Land in Summit City

    Commercial land available for rent in Summit City, New Jersey.

    789 Springfield Ave, Summit, NJ 07901
    View details
    Customizable Commercial Space for Lease
    $3,000 /Mo

    Customizable Commercial Space for Lease

    Flexible commercial space suitable for various business types.

    1228 Springfield Ave, Irvington, NJ 7111
    View details
    Commercial Land at Major Intersection
    $400,000

    Commercial Land at Major Intersection

    8 acres of commercial land for ground lease.

    12640 Lord Fairfax Hwy, Boyce, VA 22620
    View details
    Commercial Land in High-Traffic Area
    $1,000 /Mo

    Commercial Land in High-Traffic Area

    0.18 acre vacant lot with high visibility and traffic.

    586 Montauk Highway, Shirley, NY 11967
    View details

    Lewes, DE Office properties & Spaces Leasing Opportunities Market Analysis

    Explore Office properties & Spaces leasing options in Lewes, DE with 6 listings featured on our commercial real estate exchange. The current inventory includes 2,306,467,118 square feet of properties with an estimated lease value of $48 SF/Yr.

    Estimated lease rates for Office properties & Spaces in Lewes, DE begin at $23 SF/Yr, with an average of $24 SF/Yr and extend to $25 SF/Yr.
    List
    Map

    Browse Office properties & Spaces for Lease Near Lewes, DE

    Popular Searches in Lewes, DE

    Popular Categories

    Most Searched ZIP Codes in Lewes, DE

    • 19958

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!