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    Florence, CO
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    Florence, CO Office Spaces for Lease

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    Canon City, CO Pueblo, CO Pueblo West, CO
    Central Florence Office Building
    Updated: Nov 25, 2025
    Central Florence Office Building

    521 W 5th St, Florence, CO

    Contact for pricing
    4,786 sqft
    Well‑maintained office building suitable for immediate occupancy.
    Abundant off‑street parking.
    Versatile layout with classrooms, offices, and open work areas.
    Includes a break room and administrative areas.
    Previously used as a medical training center, suggesting suitability for similar uses.
    View details
    Medical Office Building For Sale
    Updated: Nov 25, 2025
    Medical Office Building For Sale

    515 W 3rd St, Florence, CO

    Contact for pricing
    2,800 sqft
    Directly across from City Hall (prime central location)
    Medical office building
    Brand new tenant improvements
    Never been occupied
    Features 6 exam rooms
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    Turn Any Listing Into an Investment Snapshot Owner equity, real caprate, demand score for every listing. Go To Analytics Center
    Based on your search, we've compiled 12 Potential Opportunities for your consideration. Besides 2 Active listings in Florence, CO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 2 Properties for Sales.

    Office Spaces for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Second-Floor Office Suite
    Second-Floor Office Suite

    346 S Orchard Springs Dr, Pueblo West, CO 81007

    Contact for pricing

    Flexible open layout with reception area, built-ins, in-suite plumbing, and access to a shared restroom.

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    Private Office Suite for Service Use
    Private Office Suite for Service Use

    346 S Orchard Springs Dr, Pueblo West, CO 81007

    Contact for pricing

    Bright private suite with natural light, in-suite sink, and shared restroom access for client-facing businesses.

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    Professional Office Space Available
    Professional Office Space Available

    2099 W US Hwy 50, Pueblo, CO 81008

    Contact for pricing

    Office space in Pueblo with Highway 50 exposure.

    View details
    Spacious Office with Open Layout
    Spacious Office with Open Layout

    3715 Thatcher Ave, Pueblo, CO 81005

    Contact for pricing

    Office space featuring open layout, kitchen, and ample parking.

    View details

    Similar Spaces for Sale in Florence, CO

    Consider Similar Space for Sale. We found 2 Spaces matching your search parameters.

    Two-Home Historic Victorian Property
    Two-Home Historic Victorian Property

    225-229 E Main Street, Florence, CO 81226

    $875,000
    1.49 AC lot

    Historic Victorian with two detached garages, workshop, and distinctive koi ponds on a landscaped lot.

    View details
    Historic Mixed-Use Property in Florence
    Historic Mixed-Use Property in Florence

    119 W Main Street, Florence, CO 81226

    $480,000
    2,850 sqft · 0.08 AC lot

    Mixed-use property with business spaces and luxury loft in Florence.

    View details

    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Space Near Light Rail
    Commercial Space Near Light Rail

    3006 Welton Street, Denver, CO 80205

    $4,000/Mo
    1,186 sqft · $40 SF/Yr

    Commercial space for rent near light rail with TI allowance.

    View details
    Los Ranchos Commercial Land For Rent
    Los Ranchos Commercial Land For Rent

    6401 4th Street NW, Los Ranchos, NM 87107

    $1,000/Mo

    High-traffic commercial land with excellent visibility in Los Ranchos, NM.

    View details
    Prime Commercial Land For Rent
    Prime Commercial Land For Rent

    11488 S State St, Draper, UT 84020

    Contact for pricing

    State Street frontage in Draper's commercial corridor, freeway visible.

    View details
    El Paso Land For Rent
    El Paso Land For Rent

    9400 Stonewall Road, El Paso, TX 79924

    $160,000 SF/Yr

    Commercial land available for rent in El Paso, Texas.

    View details

    Florence, CO Office Spaces Market Trends and Statistics

    Explore Office Spaces leasing options in Florence, CO with 2 listings featured on our commercial real estate exchange. The current inventory includes 7,586 square feet of properties with an estimated lease value of $0.00 SF/Yr.

    Estimated lease rates for Office Spaces in Florence, CO begin at $0.00 SF/Yr, with an average of $0.00 SF/Yr and extend to $0.00 SF/Yr.
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