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    Santa Cruz, CA Office Properties & Spaces for Lease

    24 results
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    Downtown Santa Cruz Office Building
    $4,000 / Mo
    2,060 SF

    Downtown Santa Cruz Office Building

    129 Water St, Santa Cruz, CA 95060

    Freestanding commercial office building in the heart of downtown Santa Cruz.

    • Freestanding commercial office building in the heart of downtown Santa Cruz.
    • Move‑in ready condition for owner‑occupant or tenant.
    • 10 offices, 2 conference rooms, and a large reception area.
    • Modern infrastructure with controlled door access, security cameras, and prominent street signage.
    • 4 on‑site parking spaces and excellent walkability to downtown amenities.
    Updated: Oct 6, 2025
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    Santa Cruz Office Space Available
    $1.55 SF/Yr
    9,000 SF

    Santa Cruz Office Space Available

    2880 Soquel Ave, Santa Cruz, CA 95062

    Highly visible office space for lease in Santa Cruz.

    • High visibility location at Soquel/Highway 1 interchange.
    • Excellent Highway 1 freeway access (north and south).
    • Ample parking (5/1,000).
    • Divisible ground floor space (to approx. 3,500 sf).
    • Significant square footage available (17,500 sf total).
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    Live Oak Commercial Office Space
    $1.50 SF/Yr
    2,100 SF

    Live Oak Commercial Office Space

    2,100 SF office space in residential Live Oak.

    2215 7Th Ave, Santa Cruz, CA 95062
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    Second Story Office Suites For Rent
    $1.85 SF/Yr
    484 SF

    Second Story Office Suites For Rent

    Second story office suites with high ceilings and natural light.

    1205 Pacific Ave, Santa Cruz, CA 95060
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    Downtown Santa Cruz Office Space
    $1.65 SF/Yr
    1,170 SF

    Downtown Santa Cruz Office Space

    Class A office suites available for rent in downtown Santa Cruz.

    133 Mission St, Santa Cruz, CA 95060
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    Santa Cruz Office Space Available
    $2 SF/Yr
    768 SF

    Santa Cruz Office Space Available

    Office space for rent in prime Santa Cruz location.

    1667 Dominican Way, Santa Cruz, CA 95065
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    Santa Cruz Office Space Available
    $1.40 SF/Yr
    1,976 SF

    Santa Cruz Office Space Available

    Office space for rent in a desirable Santa Cruz location.

    207 Mcpherson St, Santa Cruz, CA 95060
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    Santa Cruz Office Space Available
    Contact for pricing
    950 SF

    Santa Cruz Office Space Available

    950 SF office space with ample parking in Santa Cruz.

    550 Water St, Santa Cruz, CA 95060
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    Renovated Office Space Available
    Contact for pricing
    559 SF

    Renovated Office Space Available

    Newly renovated office suites with elevator access, natural light.

    903 Pacific Ave, Santa Cruz, CA 95060
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    Professional Office Suites for Lease
    Contact for pricing
    971 SF

    Professional Office Suites for Lease

    Multiple office suites available in professional building with natural light.

    500 Chestnut St, Santa Cruz, CA 95060
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    Ground Floor Commercial Space Available
    Contact for pricing
    4,430 SF

    Ground Floor Commercial Space Available

    Commercial space for lease, formerly a bank, with ample parking.

    3001 Thurber Ln, Santa Cruz, CA 95065
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    Westside Santa Cruz Flex Space
    Contact for pricing
    9,251 SF

    Westside Santa Cruz Flex Space

    9,251 SF flex space in thriving Westside Santa Cruz.

    2161 Delaware Ave, Santa Cruz, CA 95060
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    Santa Cruz Office Space Available
    Contact for pricing
    805 SF

    Santa Cruz Office Space Available

    Office space for rent in a desirable Santa Cruz location.

    700-704 Soquel Ave, Santa Cruz, CA 95062
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    West Side Santa Cruz Flex Space
    Contact for pricing
    6,800 SF

    West Side Santa Cruz Flex Space

    Vibrant retail/industrial area with flexible office and open floorplans.

    2125 Delaware Ave, Santa Cruz, CA 95060
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    Furnished Office Space in Santa Cruz
    Contact for pricing
    12,182 SF

    Furnished Office Space in Santa Cruz

    High-end, fully furnished office space in premier city center location.

    1349-1395 Pacific Ave, Santa Cruz, CA 95060
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    Equipped Lab and Office Space
    Contact for pricing
    6,750 SF

    Equipped Lab and Office Space

    6,750 SF lab and office space for rent.

    250 Natural Bridges Dr, Santa Cruz, CA 95060
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    Iconic Building in Premier Location
    Contact for pricing
    2,597 SF

    Iconic Building in Premier Location

    Office space with excellent views and convenient downtown access.

    110 Cooper St, Santa Cruz, CA 95060
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    Office Space with Ample Parking
    Contact for pricing
    720 SF

    Office Space with Ample Parking

    Office space featuring ample parking and an open floor plan.

    9029 Soquel Ave, Santa Cruz, CA 95062
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    Santa Cruz Office Space Available
    Contact for pricing
    6,250 SF

    Santa Cruz Office Space Available

    Office space for rent in Santa Cruz, California.

    1121 Pacific Ave, Santa Cruz, CA 95060
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    Retail/Office Space in Santa Cruz
    $2,500 / Mo
    3,135 SF

    Retail/Office Space in Santa Cruz

    3135 SF retail or office space available for rent.

    Cooper St, Santa Cruz, CA 95060
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    Downtown Santa Cruz Office Space
    Contact for pricing

    Downtown Santa Cruz Office Space

    Office space for rent in the heart of Santa Cruz.

    1200 Pacific Ave #Ground, Santa Cruz, CA 95060
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    Santa Cruz Office Space for Lease
    $18 SF/Yr
    11,826 SF

    Santa Cruz Office Space for Lease

    Prime Santa Cruz Office, 742 sq ft.

    501 Mission St, Santa Cruz, CA 95060
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    Santa Cruz Office Suites for Lease
    $20 SF/Yr
    7,000 SF

    Santa Cruz Office Suites for Lease

    Prime Santa Cruz location, flexible office spaces.

    542 Ocean St, Santa Cruz, CA 95060
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    Mission Drive Medical Office
    $33 SF/Yr
    2,676 SF

    Mission Drive Medical Office

    Santa Cruz medical office space available.

    3321 Mission Dr, Santa Cruz, CA 95065
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    Based on your search, we've compiled 30 Potential Opportunities for your consideration. Besides 24 Active listings in Santa Cruz, CA, we suggest exploring alternatives. Consider Similar 6 Spaces for Sales.

    Santa Cruz, CA Office Properties & Spaces Leasing Opportunities Market Analysis

    Explore Office Properties & Spaces leasing options in Santa Cruz, CA with 30 listings featured on our commercial real estate exchange. The current inventory includes 1,838,014,200 square feet of properties with an estimated lease value of $114 SF/Yr.

    Estimated lease rates for Office Properties & Spaces in Santa Cruz, CA begin at $1.40 SF/Yr, with an average of $10 SF/Yr and extend to $33 SF/Yr.
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    Browse Office Properties & Spaces for Lease Near Santa Cruz, CA

    Popular Searches in Santa Cruz, CA

    Most Searched ZIP Codes in Santa Cruz, CA

    • 95060
    • 95062
    • 95065
    • 92701

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