Advertise
    Santa Cruz, CA

    Santa Cruz, CA Commercial Real Estate for Lease

    Notify Me
    List
    Map
    Capitola, CA Scotts Valley, CA Aptos, CA Boulder Creek, CA Watsonville, CA Freedom, CA Los Gatos, CA Saratoga, CA
    29 properties
    Sort:
    Downtown Class A Office Suites
    Updated: Jul 24
    Downtown Class A Office Suites

    133 Mission St, Santa Cruz, CA 95060

    $4,909/Mo
    4,909 sqft
    Class A office space in downtown Santa Cruz, available now
    Free parking available at 4 per 1,000 SF
    Available suites: Suite 220 (~1,053 SF), Suite 210 (~2,668 SF), Suite 230 (~1,170 SF), Suite 240 (~1,266 SF)
    Multi‑suite option: Suite 210+220+230+240 totaling approximately 6,157 SF
    View details
    Available Office Unit
    Updated: Aug 1
    Available Office Unit

    133 Mission St, Suite 280, Santa Cruz, CA 95060

    $4,909/Mo
    4,909 sqft
    Office unit available now
    Suite 280 at 133 Mission St, Santa Cruz, CA 95060
    Listed property size of 4,909
    View details
    Santa Cruz Office Space Available
    Santa Cruz Office Space Available

    133 Mission St, Suite 210, Santa Cruz, CA 95060

    $2,668/Mo
    2,668 sqft

    Office space available for rent in Santa Cruz, CA.

    View details
    Elevator-Served Office Units
    Elevator-Served Office Units

    1121-1125 Pacific Ave, Santa Cruz, CA 95060

    Contact for pricing
    10,204 sqft

    Flexible professional workspace with modern amenities, elevator service, and abundant natural light.

    View details
    Mixed-Use Suite with Display Windows
    Mixed-Use Suite with Display Windows

    6892 Soquel Ave, Santa Cruz, CA 95062

    Contact for pricing
    1,160 sqft

    Two levels offer open areas, private office or storage space, a kitchenette, and a private bathroom.

    View details
    Medical Office Space with Clinic History
    Medical Office Space with Clinic History

    220 Leibrandt Ave, Santa Cruz, CA 95060

    Contact for pricing
    1,560 sqft

    Former dental clinic space identified for office, medical, dental, veterinary, and retail uses.

    View details
    Freestanding Single-Tenant Office
    Freestanding Single-Tenant Office

    617 Water St, Santa Cruz, CA 95060

    Contact for pricing
    1,500 sqft

    Freestanding office features a large entry open area, full kitchen/break area, multiple private offices, and 6 parking spaces.

    View details
    Grade-Level Office Space
    Grade-Level Office Space

    601 Swift St, Santa Cruz, CA 95060

    Contact for pricing
    20,200 sqft

    Turnkey office suite with robust 1,200-amp power service and surface parking available starting August 15, 2026.

    View details
    Retail Shopping Center with Parking
    Retail Shopping Center with Parking

    580 River St, Santa Cruz, CA 95060

    Contact for pricing
    1,372 sqft

    Shopping center offering 498 dedicated parking stalls and major retail anchors including ROSS, PetSmart, and Cost Plus World Market.

    View details
    Retail Space in Santa Cruz
    Retail Space in Santa Cruz

    414 Front St, Santa Cruz, CA 95060

    Contact for pricing
    11,479 sqft

    Retail space available for lease in Santa Cruz, CA.

    View details
    Mixed-Use Village with Retail Courtyard
    Mixed-Use Village with Retail Courtyard

    300 Ingalls St, Santa Cruz, CA 95060

    Contact for pricing
    5,000 sqft

    Planned mixed-use community includes three 4-story residential buildings and a retail plaza with an outdoor courtyard.

    View details
    Retail Space on Pacific Avenue
    Retail Space on Pacific Avenue

    1117 Pacific Ave, Santa Cruz, CA 95060

    $15 SF/Yr

    Retail space available for rent on Pacific Avenue.

    View details
    Santa Cruz Office Space Available
    Santa Cruz Office Space Available

    550 Water St, Santa Cruz, CA

    Contact for pricing
    950 sqft 0.66 AC lot

    950 SF office space with ample parking in Santa Cruz.

    View details
    Downtown Retail Space Available
    Downtown Retail Space Available

    1115-1117 Pacific Ave, Santa Cruz, CA

    Contact for pricing
    3,500 sqft 0.18 AC lot

    Retail space in a vibrant downtown location on Pacific Avenue.

    View details
    Downtown Office Space with Parking
    Downtown Office Space with Parking

    1543 Pacific Ave, Santa Cruz, CA 95060

    Contact for pricing

    Flexible office layout includes private offices, open work areas, conference room, and two restrooms, with on-site parking.

    View details
    Westside Flex Space with Mezzanine
    Westside Flex Space with Mezzanine

    411 Ingalls St, Santa Cruz, CA

    Contact for pricing
    4,000 sqft 0.25 AC lot

    Flexible industrial space with mezzanine in prime westside location.

    View details
    Mixed-Use Property
    Mixed-Use Property

    101 Church Street, Santa Cruz, CA 95060

    Contact for pricing

    Commercial space combines office and retail functions in a lease offering.

    View details
    Mixed-Use Development Retail Space
    Mixed-Use Development Retail Space

    418-508 Front St, Santa Cruz, CA

    Contact for pricing
    1,744 sqft 1.04 AC lot

    Retail space in a mixed-use development with residential units.

    View details
    Mixed-Use Property with Signage
    Mixed-Use Property with Signage

    6894 Soquel Avenue, Santa Cruz, CA 95062

    Contact for pricing

    Retail, office, and professional service uses are identified for this Soquel Avenue space.

    View details
    Renovated Retail Space, Former Bank
    Renovated Retail Space, Former Bank

    1128-1134 Pacific Ave, #1130, Santa Cruz, CA 95060

    $39 SF/Yr

    Renovated retail space, previously a Bank of America branch.

    View details
    Retail Space on Pacific Avenue
    Retail Space on Pacific Avenue

    1010 Pacific Ave, Santa Cruz, CA

    Contact for pricing
    1,266 sqft 0.64 AC lot

    Retail space available on busy corner with excellent visibility.

    View details
    Boutique Hotel with Kitchenettes
    Boutique Hotel with Kitchenettes

    21305 E Cliff Drive, Santa Cruz, CA 95062

    Contact for pricing

    A two-story lodging property offers in-room kitchenettes and a twelve-room configuration.

    View details
    Equipped Lab and Office Space
    Equipped Lab and Office Space

    250 Natural Bridges Dr, Santa Cruz, CA

    Contact for pricing
    6,750 sqft 0.91 AC lot

    6,750 SF lab and office space for rent.

    View details
    Professional Office Suites for Lease
    Professional Office Suites for Lease

    500 Chestnut St, Santa Cruz, CA

    Contact for pricing
    971 sqft 0.30 AC lot

    Multiple office suites available in professional building with natural light.

    View details

    Santa Cruz, CA Commercial real estate Market Trends and Statistics

    Explore Commercial real estate leasing options in Santa Cruz, CA with 29 listings featured on our commercial real estate exchange. The current inventory includes 86,386 square feet of properties with an estimated lease value of $132.

    Estimated lease rates for Commercial real estate in Santa Cruz, CA begin at $12 SF/Yr, with an average of $22 SF/Yr and extend to $42 SF/Yr.
    Santa Cruz, CA CRE market trends — vacancy, lease rates and price per SF, updated monthly
    List
    Map

    Browse Commercial real estate for Lease Near Santa Cruz, CA

    Popular Searches in Santa Cruz, CA

    Popular Categories

    Most Searched ZIP Codes in Santa Cruz, CA

    • 95060
    • 95062
    Why this one?
    Saved
    Reason not saved — we won't ask again

    Select Neighborhood

    Google sign-in failed. Please try again or use another login method.
    Sign Up Successful!
    You now have access to more from Realmo!