Santa Cruz, CA Office Spaces for Rent & Lease

Updated: Aug 1

Available Office Unit

133 Mission St, Suite 280, Santa Cruz, CA 95060

$4,909/Mo

4,909 sqft

Office unit available now
Suite 280 at 133 Mission St, Santa Cruz, CA 95060
Listed property size of 4,909

View details

Updated: Apr 4

Santa Cruz Office Space Available

133 Mission St, Suite 210, Santa Cruz, CA 95060

$2,668/Mo

2,668 sqft

Available now

View details

Freestanding Single-Tenant Office

617 Water St, Santa Cruz, CA 95060

Contact for pricing

1,500 sqft

Freestanding office features a large entry open area, full kitchen/break area, multiple private offices, and 6 parking spaces.

View details

Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Grade-Level Office Space

601 Swift St, Santa Cruz, CA 95060

Contact for pricing

20,200 sqft

Turnkey office suite with robust 1,200-amp power service and surface parking available starting August 15, 2026.

View details

Downtown Class A Office Suites

133 Mission St, Santa Cruz, CA 95060

Contact for pricing

2,668 sqft

Class A office suites are available now in downtown Santa Cruz, with free parking included.

View details

Downtown Office Space with Parking

1543 Pacific Ave, Santa Cruz, CA 95060

Contact for pricing

4,371 sqft

Flexible office layout includes private offices, open work areas, conference room, and two restrooms, with on-site parking.

View details

Office Units with Private Restrooms

550 Water St, Santa Cruz, CA 95060

Contact for pricing

950 sqft

Three bright office suites provide private restroom access and ample parking for commercial occupants.

View details

Santa Cruz Office Space Available

550 Water St, Santa Cruz, CA

Contact for pricing

950 sqft 0.66 AC lot

950 SF office space with ample parking in Santa Cruz.

View details

Santa Cruz Office Space Available

1667 Dominican Way, Santa Cruz, CA

Contact for pricing

768 sqft 0.03 AC lot

Office space for rent in prime Santa Cruz location.

View details

Downtown Office Building

1200 Pacific Ave, Santa Cruz, CA 95060

Contact for pricing

20,026 sqft

Office building with network wiring and strong natural light, plus a walkway connecting floors to the parking structure.

View details

Equipped Lab and Office Space

250 Natural Bridges Dr, Santa Cruz, CA

Contact for pricing

6,750 sqft 0.91 AC lot

6,750 SF lab and office space for rent.

View details

Medical Office Suite

626 Frederick St, Santa Cruz, CA 95062

Contact for pricing

Ground-floor space includes treatment rooms, reception, kitchen, and utility areas.

View details

Professional Office Suites for Lease

500 Chestnut St, Santa Cruz, CA

Contact for pricing

971 sqft 0.30 AC lot

Multiple office suites available in professional building with natural light.

View details

Class A Office Suites with Free Parking

133 Mission St, Santa Cruz, CA 95060

Contact for pricing

1,170 sqft

Class A office suites available now, offering free parking and multiple suite size options.

View details

Class A Office Suites

133 Mission St, Santa Cruz, CA 95060

Contact for pricing

1,266 sqft

Class A office suites in downtown Santa Cruz with free on-site parking and suites available now.

View details

Class A Office Suites Downtown

133 Mission St, Santa Cruz, CA 95060

Contact for pricing

1,053 sqft

Downtown Santa Cruz offers Class A office suites with free parking and immediate availability.

View details

Downtown Santa Cruz Office Space

1200 Pacific Ave, #Ground Floor, Santa Cruz, CA 95060

Contact for pricing

Office space for rent in the heart of Santa Cruz.

View details

Commercial Space Available For Lease

2450 17th Ave, Santa Cruz, CA 95062

Contact for pricing

Commercial property available for lease in Santa Cruz, California.

View details

Newly Renovated Office Suites

903 Pacific Ave, Santa Cruz, CA 95060

Contact for pricing

268 sqft

Newly renovated second- and third-floor office suites with elevator service and natural light.

View details

Downtown Santa Cruz Office Space

312 Lincoln St, Santa Cruz, CA 95060

Contact for pricing

Open office space in downtown Santa Cruz with parking.

View details

Two-Story Office Building

2880 Soquel Ave, Santa Cruz, CA 95062

Contact for pricing

9,000 sqft

Two-story, elevator-served office building with divisible ground floor space and additional basement and upstairs options.

View details

Renovated Second-Floor Office Suites

903 Pacific Ave, Santa Cruz, CA 95060

Contact for pricing

732 sqft

Newly renovated 2nd and 3rd floor office suites with elevator service and natural light.

View details

Renovated Office Suites with Elevator

903 Pacific Ave, Santa Cruz, CA 95060

Contact for pricing

559 sqft

Newly renovated second- and third-floor office suites with elevator service and natural light windows.

View details

Renovated Office Space Available

903 Pacific Ave, Santa Cruz, CA

Contact for pricing

559 sqft 0.17 AC lot

Newly renovated office suites with elevator access, natural light.

View details

Santa Cruz, CA Office Spaces Lease Rates & Market Statistics

Browse 25 Office Spaces for lease in Santa Cruz, CA on Realmo, a commercial real estate marketplace serving the Santa Cruz area. The current inventory totals 82,749 square feet of properties — an average of ~3,300 SF per listing.

Asking lease rates for Office Spaces in Santa Cruz start at $12 SF/Yr, average $12 SF/Yr, and reach $12 SF/Yr at the top of the market. Pricing across the market is relatively uniform, which simplifies like-for-like comparison between listings. At $12 SF/Yr, the local average runs 52% below California's state average of $24.81 SF/Yr.

Santa Cruz accounts for 50% of the 50 office spaces currently available across Santa Cruz County, where nearby markets include Scotts Valley and Los Gatos. By space type, the market includes 19 office units and 5 office buildings.