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    Santa Cruz, CA Commercial Real Estate for Lease

    48 results
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    Retail Space in Santa Cruz
    $4,500 / Mo
    1,500 SF

    Retail Space in Santa Cruz

    805 Ocean St, Santa Cruz, CA 95060

    High-visibility retail location with significant traffic in Santa Cruz.

    • High visibility retail location at major intersection of Ocean St. and Water St.
    • High traffic count: over 20,000 cars pass per day.
    • Adjacent to Santa Cruz County Center.
    • Parking available.
    • Wheelchair accessible with ramp.
    Updated: Feb 6
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    Downtown Santa Cruz Office Building
    $4,000 / Mo
    2,060 SF

    Downtown Santa Cruz Office Building

    129 Water St, Santa Cruz, CA 95060

    Freestanding commercial office building in the heart of downtown Santa Cruz.

    • Freestanding commercial office building in the heart of downtown Santa Cruz.
    • Move‑in ready condition for owner‑occupant or tenant.
    • 10 offices, 2 conference rooms, and a large reception area.
    • Modern infrastructure with controlled door access, security cameras, and prominent street signage.
    • 4 on‑site parking spaces and excellent walkability to downtown amenities.
    Updated: Oct 6, 2025
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    Santa Cruz Office Space Available
    $1.55 SF/Yr
    9,000 SF

    Santa Cruz Office Space Available

    Highly visible office space for lease in Santa Cruz.

    2880 Soquel Ave, Santa Cruz, CA 95062
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    Live Oak Commercial Office Space
    $1.50 SF/Yr
    2,100 SF

    Live Oak Commercial Office Space

    2,100 SF office space in residential Live Oak.

    2215 7Th Ave, Santa Cruz, CA 95062
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    Second Story Office Suites For Rent
    $1.85 SF/Yr
    484 SF

    Second Story Office Suites For Rent

    Second story office suites with high ceilings and natural light.

    1205 Pacific Ave, Santa Cruz, CA 95060
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    Retail Space in New Complex
    $1.25 SF/Yr
    965 SF

    Retail Space in New Complex

    Retail storefronts in a high-traffic, walkable Santa Cruz location.

    350 Ocean St, Santa Cruz, CA 95060
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    Downtown Santa Cruz Office Space
    $1.65 SF/Yr
    1,170 SF

    Downtown Santa Cruz Office Space

    Class A office suites available for rent in downtown Santa Cruz.

    133 Mission St, Santa Cruz, CA 95060
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    Santa Cruz Office Space Available
    $2 SF/Yr
    768 SF

    Santa Cruz Office Space Available

    Office space for rent in prime Santa Cruz location.

    1667 Dominican Way, Santa Cruz, CA 95065
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    Santa Cruz Office Space Available
    $1.40 SF/Yr
    1,976 SF

    Santa Cruz Office Space Available

    Office space for rent in a desirable Santa Cruz location.

    207 Mcpherson St, Santa Cruz, CA 95060
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    Santa Cruz Office Space Available
    Contact for pricing
    950 SF

    Santa Cruz Office Space Available

    950 SF office space with ample parking in Santa Cruz.

    550 Water St, Santa Cruz, CA 95060
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    Renovated Office Space Available
    Contact for pricing
    559 SF

    Renovated Office Space Available

    Newly renovated office suites with elevator access, natural light.

    903 Pacific Ave, Santa Cruz, CA 95060
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    West Santa Cruz Retail Space
    Contact for pricing
    3,770 SF

    West Santa Cruz Retail Space

    Premier shopping center space in established Santa Cruz neighborhood.

    841 Almar Ave, Santa Cruz, CA 95060
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    Professional Office Suites for Lease
    Contact for pricing
    971 SF

    Professional Office Suites for Lease

    Multiple office suites available in professional building with natural light.

    500 Chestnut St, Santa Cruz, CA 95060
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    Ground Floor Commercial Space Available
    Contact for pricing
    4,430 SF

    Ground Floor Commercial Space Available

    Commercial space for lease, formerly a bank, with ample parking.

    3001 Thurber Ln, Santa Cruz, CA 95065
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    Santa Cruz Retail Spaces Available
    Contact for pricing
    1,920 SF

    Santa Cruz Retail Spaces Available

    Retail spaces available in premier Santa Cruz shopping center.

    849 Almar Ave, Santa Cruz, CA 95060
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    Retail Spaces with Yard Area
    Contact for pricing
    2,538 SF

    Retail Spaces with Yard Area

    Retail spaces available with ample parking and outdoor areas.

    21501 E Cliff Dr, Santa Cruz, CA 95062
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    Westside Santa Cruz Flex Space
    Contact for pricing
    9,251 SF

    Westside Santa Cruz Flex Space

    9,251 SF flex space in thriving Westside Santa Cruz.

    2161 Delaware Ave, Santa Cruz, CA 95060
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    Santa Cruz Office Space Available
    Contact for pricing
    805 SF

    Santa Cruz Office Space Available

    Office space for rent in a desirable Santa Cruz location.

    700-704 Soquel Ave, Santa Cruz, CA 95062
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    Retail Spaces with Yard Area
    Contact for pricing
    1,685 SF

    Retail Spaces with Yard Area

    Retail spaces available with ample parking and outdoor areas.

    21507-21517 E Cliff Dr, Santa Cruz, CA 95060
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    West Side Santa Cruz Flex Space
    Contact for pricing
    6,800 SF

    West Side Santa Cruz Flex Space

    Vibrant retail/industrial area with flexible office and open floorplans.

    2125 Delaware Ave, Santa Cruz, CA 95060
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    Retail Space on Soquel Avenue
    Contact for pricing
    1,350 SF

    Retail Space on Soquel Avenue

    Retail space with high visibility on a busy corner.

    1822 Soquel Ave, Santa Cruz, CA 95062
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    Downtown Santa Cruz Retail Space
    Contact for pricing
    4,622 SF

    Downtown Santa Cruz Retail Space

    New retail space in mixed-use building, prime downtown location.

    800 Pacific Ave, Santa Cruz, CA 95060
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    Furnished Office Space in Santa Cruz
    Contact for pricing
    12,182 SF

    Furnished Office Space in Santa Cruz

    High-end, fully furnished office space in premier city center location.

    1349-1395 Pacific Ave, Santa Cruz, CA 95060
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    Equipped Lab and Office Space
    Contact for pricing
    6,750 SF

    Equipped Lab and Office Space

    6,750 SF lab and office space for rent.

    250 Natural Bridges Dr, Santa Cruz, CA 95060
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    Santa Cruz, CA Commercial real estate Leasing Opportunities Market Analysis

    Explore Commercial real estate leasing options in Santa Cruz, CA with 69 listings featured on our commercial real estate exchange. The current inventory includes 3,993,101,640 square feet of properties with an estimated lease value of $239 SF/Yr.

    Estimated lease rates for Commercial real estate in Santa Cruz, CA begin at $1.25 SF/Yr, with an average of $14 SF/Yr and extend to $48 SF/Yr.
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    Browse Commercial real estate for Lease Near Santa Cruz, CA

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