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San Leandro, CA Office Spaces for Lease

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Medical Office Suite with Reception Area
Updated: Jul 17
Medical Office Suite with Reception Area

148 Best Ave, San Leandro, CA 94577

$1,800/Mo
2,244 sqft 0.10 AC lot
2,244 SF medical office space with four separate office suites
Two office suites include existing sinks
Formal waiting room with receptionist station
Kitchen, bathroom, and multiple storage closets
At Best Ave and E 14th St in San Leandro
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Professional Office Suite with Parking
Updated: Jun 3
Professional Office Suite with Parking

1133 San Leandro Blvd, San Leandro, CA 94577

$3,850/Mo
1,875 sqft
Approximately 1,875 SF professional office space available for lease.
Functional layout includes foyer/reception area, 2 private offices, and a large conference room.
Rear open workspace plus private restroom.
Abundant natural light throughout.
Large on‑site parking lot for convenient access for employees and clients.
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Medical-Pro Office Suite
Medical-Pro Office Suite

148 Best Ave, San Leandro, CA 94577

$1,800/Mo

Suite includes a waiting/reception area, kitchen, bathroom, and multiple office rooms, with two offices featuring sinks.

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Medical Office Building with Heavy Power
Medical Office Building with Heavy Power

15555 E 14th St, San Leandro, CA 94578

Contact for pricing
4,293 sqft

Zoned for medical use with plentiful surface parking and flexible suite sizes up to 10,000 SF.

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Single-Story Medical Office Suite
Single-Story Medical Office Suite

595 Estudillo Ave, San Leandro, CA 94577

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1,479 sqft

Suite includes multiple exam and treatment rooms with plumbing, a large waiting area, and 4 reserved parking stalls.

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San Leandro Warehouse Sublease Available
San Leandro Warehouse Sublease Available

1991 Burroughs Avenue, San Leandro, CA 94577

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8,400 sqft

8,400 SF sublease with office space and loading dock.

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San Leandro Medical/Professional Office
San Leandro Medical/Professional Office

595 Estudillo Ave, San Leandro, CA 94577

Contact for pricing
1,479 sqft

Well-situated medical/professional services/office/retail space in San Leandro, CA.

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Office Building with Fenced Yard
Office Building with Fenced Yard

2101 Carden St, San Leandro, CA 94577

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1,848 sqft 0.45 AC lot

Single-tenant office space in a 1981 building with a fenced, paved, and lit yard.

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San Leandro Medical/Professional Office Space
San Leandro Medical/Professional Office Space

595 Estudillo Ave, San Leandro, CA 94577

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4,506 sqft

Medical/Professional Services/Office/Retail space available in San Leandro, CA.

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San Leandro Office Space Available
San Leandro Office Space Available

1821-1831 Merced St, San Leandro, CA 94577

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2,084 sqft

Office space with private offices, conference room, and shared breakroom.

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Flex Space with Grade-Level Doors
Flex Space with Grade-Level Doors

2761 Teagarden St, San Leandro, CA 94578

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19,813 sqft

Industrial flex property combines warehouse and office areas with freeway visibility and signage opportunities.

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Flex Space with Open Seating
Flex Space with Open Seating

15555 E 14th St, San Leandro, CA 94578

Contact for pricing
3,478 sqft

Flex space with kitchenette and flexible R&D layout, plus ample 480v or 220v power for equipment and venting needs.

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Professional Office Suite Sublease
Professional Office Suite Sublease

433 Callan Ave, San Leandro, CA 94577

Contact for pricing
2,332 sqft

Office suite includes 5–6 private offices, a conference room, and kitchen and storage space.

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Flex Restaurant Kitchen Space
Flex Restaurant Kitchen Space

15555 E 14th St, San Leandro, CA 94578

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50,152 sqft

Flex space with an existing test kitchen setup, venting for fume hoods, and polished concrete floors.

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San Leandro Single Tenant Office
San Leandro Single Tenant Office

1933 Davis St, San Leandro, CA 94577

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31,070 sqft

Single tenant office building available for rent in San Leandro.

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Flex Space with Drive-In Truck Doors
Flex Space with Drive-In Truck Doors

2400-2496 Teagarden St, San Leandro, CA 94577

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1,440 sqft

Flex space offering private offices, drive-in truck doors, and sprinklered warehouse space.

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San Leandro Office Space Available
San Leandro Office Space Available

1040 Davis St, San Leandro, CA

Contact for pricing
2,242 sqft 0.45 AC lot

Office space available for lease in San Leandro, California.

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Based on your search, we've compiled 29 Potential Opportunities for your consideration. Besides 17 Active listings in San Leandro, CA, we suggest exploring alternatives. Similar 12 Properties for Sales.

Similar Spaces for Sale in San Leandro, CA

Consider Similar Space for Sale. We found 12 Spaces matching your search parameters.

Six-Parcel Retail Office Portfolio
Six-Parcel Retail Office Portfolio

601 99 E 14th Street, San Leandro, CA 94577

$8,500,000
26,150 sqft 0.90 AC lot

Six contiguous retail and office parcels with mixed tenants, including vacant and month-to-month suites.

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Two-Story Mixed-Use Building
Two-Story Mixed-Use Building

635 E 14Th St, San Leandro, CA 94577

$1,060,000
3,470 sqft 0.05 AC lot

Two-story mixed-use property with ground-floor restaurant space and three second-floor office suites, two currently leased.

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Office Building with Detached Garage
Office Building with Detached Garage

370 E 14Th St, San Leandro, CA 94577

$495,000
1,401 sqft 0.12 AC lot

Vacant professional property with reception, kitchenette, private office areas, accessible rear entry, and paved on-site parking.

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Live-Work Property in San Leandro
Live-Work Property in San Leandro

Alvarado St, San Leandro, CA 94577

$995,000
1,933 sqft 0.20 AC lot

Mixed-use property with residential and office space for sale.

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Mixed-Use Property in San Leandro
Mixed-Use Property in San Leandro

2144 Alvarado St, San Leandro, CA 94577

$995,000
1,933 sqft

Industrial/Residential property with office and residential units, remodeled/upgraded.

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Leased Medical Building Near Hospital
Leased Medical Building Near Hospital

13939 E 14th St, San Leandro, CA

Contact for pricing
15,152 sqft 1.14 AC lot

Fully leased medical building anchored by DaVita and Concentra.

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Office Building
Office Building

2000 East 14th Street, San Leandro, CA 94577

Contact for pricing
14,508 sqft

For-sale office building totaling 14,508 SF.

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San Leandro, CA Office Spaces Lease Rates & Market Statistics

Browse 17 Office Spaces for lease in San Leandro, CA on Realmo, a commercial real estate marketplace serving the San Leandro area. The current inventory totals 138,735 square feet of properties — an average of ~8,150 SF per listing.

Asking lease rates for Office Spaces in San Leandro start at $9.63 SF/Yr, average $17.13 SF/Yr, and reach $24.64 SF/Yr at the top of the market. That's a 3x spread between entry-level and premium space, making side-by-side comparison of asking rents and lease terms essential. The local average of $17.13 SF/Yr is 31% below the California state average of $24.90 SF/Yr.

San Leandro accounts for 2% of the 758 office spaces currently available across Alameda County, where nearby markets include Oakland and Pleasanton. By space type, the market includes 13 office units and 6 medical office space listings — medical office space options typically offer the lowest entry point, while office units command the highest rates.

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