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San Francisco, CA Office Properties & Spaces for Lease

550 results
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Mid Market
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Mid Market

Meet, work or collaborate in our professional Sawgrass Corporate Park business center

1390 Market St, San Francisco, CA 94102
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San Francisco Commercial Space Available
$8,000 / Mo
3,795 SF

San Francisco Commercial Space Available

729 Bush St, San Francisco, CA 94108

Two-story commercial building in Lower Nob Hill for rent.

  • Prime location in Lower Nob Hill, San Francisco, near Union Square and the Financial District
  • Versatile RC‑4 zoning allows for a wide range of commercial uses
  • Rare large 3,781 sq ft lot for the area
  • Excellent transportation access via BART, cable cars, and MUNI
  • Redevelopment potential, including vertical expansion and modern medical build‑outs
Updated: Dec 30, 2025
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505 Montgomery
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505 Montgomery

505 Floors, San Francisco, CA 94111

All-inclusive access to workspace, virtual office and meeting rooms in 505 Montgomery

  • Be part of a vibrant coworking community with dedicated desk or hot desking options in thousands of idyllic locations across the globe
  • Grow in a modern workplace with the added advantage of a benefits program offering exclusive discounts and bespoke procurement support
  • Access Regus' network of workspaces and business lounges as often as you need and take advantage of their exclusive benefits
  • Impress clients, hold memorable workshops, and deliver a winning pitch in Regus' meeting spaces, fully equipped for gatherings of any size
  • Collaborate with like‑minded professionals and enjoy regular networking and community events with a Regus membership
Updated: Feb 19
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California Street
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California Street

Discover many ways to work your way in California Street

50 California St, San Francisco, CA 94111
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CA, San Francisco - 580 California
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CA, San Francisco - 580 California

Flexible workspace in West Loop 200 S. Wacker

580 Floors, San Francisco, CA 94104
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Spaces Mission & 3rd
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Spaces Mission & 3rd

Discover many ways to work your way in AZ, Tempe - Hayden Ferry Lake

95 3Rd St, San Francisco, CA 94103
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Spaces Levi's Plaza
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Spaces Levi's Plaza

Discover many ways to work your way in AZ, Tempe - Hayden Ferry Lake

1160 Battery St, San Francisco, CA 94111
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CA, San Francisco - 101 Montgomery
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CA, San Francisco - 101 Montgomery

Workspaces, services and support to help you grow your business in DC, Washington - 609 H Street

101 Montgomery St, San Francisco, CA 94111
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CA, San Francisco - 71 Stevenson St
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CA, San Francisco - 71 Stevenson St

Discover many ways to work your way in Redmond Center

71 Stevenson St, San Francisco, CA 94105
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CA, San Francisco - 720 Market St
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CA, San Francisco - 720 Market St

Discover many ways to work your way in Redmond Center

720 Market St, San Francisco, CA 94210
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2143-2145 Taraval St
$39 SF/Yr

2143-2145 Taraval St

Office for Lease Sunset District, San Francisco

2143-2145 Taraval St, San Francisco, CA 94112
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868 Post St
$1,800 / Mo

868 Post St

RETAIL/OFFICE/LIGHTINDUSTRY

868 Post St, San Francisco, CA 94109
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Creative Space in SOMA District
$22 SF/Yr
62,000 SF

Creative Space in SOMA District

Unique creative space in a prime SOMA location for rent.

972 Mission St, San Francisco, CA 94103
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Move-in Ready Office Space Available
$15 SF/Yr
10,800 SF

Move-in Ready Office Space Available

Three floors of office space in a convenient San Francisco location.

1338 Mission St, San Francisco, CA 94103
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Versatile Office Space in San Francisco
$45 SF/Yr
16,900 SF

Versatile Office Space in San Francisco

Varied office solutions in a convenient Financial District location.

665 Chestnut St, San Francisco, CA 94133
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Historic Mixed-Use Complex on Van Ness
$0.74 SF/Yr
164,168 SF

Historic Mixed-Use Complex on Van Ness

Modern mixed-use complex with retail, office, and entertainment spaces.

1000 Van Ness Ave, San Francisco, CA 94109
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Modern Space in SoMa District
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Modern Space in SoMa District

Contemporary property ideal for retail, office, or showroom use.

1222 Harrison St, San Francisco, CA 94103
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Modern Office in Financial District
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Modern Office in Financial District

Class-A high-rise with on-site amenities and easy transit access.

100 1St St, San Francisco, CA 94105
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Market Street Fitness Space Available
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Market Street Fitness Space Available

Turnkey fitness space in a high-visibility, high-traffic location.

1390 Market St, San Francisco, CA 94102
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Prime Jackson Square Office Space
$39 SF/Yr
22,716 SF

Prime Jackson Square Office Space

Classic brick and timber building in Jackson Square, San Francisco.

414 Jackson St, San Francisco, CA 94111
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Hayes Valley Victorian Office Space
$42 SF/Yr
1,750 SF

Hayes Valley Victorian Office Space

Move-in ready office in a beautiful Victorian building.

257 Oak St, San Francisco, CA 94102
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Full Floor Office Space Available
$32 SF/Yr
2,900 SF

Full Floor Office Space Available

Full floor office space with excellent natural light.

3500-3502 Geary Blvd, San Francisco, CA 94118
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Full Floor Medical Office Space
$1.50 SF/Yr
4,367 SF

Full Floor Medical Office Space

Full floor medical suite with exam and private offices.

1833 Fillmore St, San Francisco, CA 94115
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1st Floor Office Space
$3 SF/Yr
1,400 SF

1st Floor Office Space

1,400 SF office space with four private offices.

3626 Sacramento St, San Francisco, CA 94118
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San Francisco, CA Office properties & Spaces Leasing Opportunities Market Analysis

Explore Office properties & Spaces leasing options in San Francisco, CA with 693 listings featured on our commercial real estate exchange. The current inventory includes 138,894,501,240 square feet of properties with an estimated lease value of $3,800 /Mo.

Estimated lease rates for Office properties & Spaces in San Francisco, CA begin at $0.74 SF/Yr, with an average of $33 SF/Yr and extend to $100 SF/Yr.
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