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Apple Valley, CA Office Properties & Spaces for Lease

24 results
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Apple Valley Commercial Space Available
$1,000 / Mo
750 SF

Apple Valley Commercial Space Available

16025 Kamana Rd, Apple Valley, CA 92307

Bottom floor office/commercial space in a high-traffic area.

  • High‑traffic location near Desert Community Bank and St. Mary's Hospital.
  • Suitable for professional office or medical use.
  • Bottom floor accessibility.
  • Anchored by a busy convenience store, providing potential customer base.
  • Gross rent includes water and trash.
Updated: Oct 28, 2025
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Professional Office Space Available
$1,707 / Mo

Professional Office Space Available

18270 Siskiyou Rd, Apple Valley, CA 92307

First-generation office suite near St. Mary's Medical Center.

  • Prime Location: Immediately north of St. Mary's Medical Center campus and one block from Highway 18, a sought‑after area for medical and professional uses.
  • Never‑Occupied Suite: First‑generation 2nd‑story unit, never been occupied.
  • Zoned Office Professional: Suitable for private office, studio, and other professional uses.
  • Open Space Plan: Flexible layout with open space.
  • New Wood Laminate Floors: Features brand new wood laminate floors.
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Apple Valley Multi-Tenant Office Space
$1.40 SF/Yr
3,840 SF

Apple Valley Multi-Tenant Office Space

Professional office suites available for lease in Apple Valley.

16048 Tuscola Rd, Apple Valley, CA 92307
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Prime Endcap Retail Unit
$1.30 SF/Yr
15,100 SF

Prime Endcap Retail Unit

Spacious retail unit in a thriving shopping center.

20162 Us Highway 18, Apple Valley, CA 92307
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Apple Valley Medical Office Space
$1.20 SF/Yr
28,929 SF

Apple Valley Medical Office Space

Well-appointed medical/professional suite in Apple Valley's medical corridor.

18523 Corwin Rd, Apple Valley, CA 92307
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Historic Apple Valley Office Space
$1,650 / Mo
64,784 SF

Historic Apple Valley Office Space

Unique office space in a historic landmark, Apple Valley Inn.

20600 Us Highway 18, Apple Valley, CA 92307
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Apple Valley Office Space Available
Contact for pricing
25,000 SF

Apple Valley Office Space Available

Corner office unit with great views and modern upgrades.

18484 Us Hwy 18 Hwy, Apple Valley, CA 92307
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Multi-Tenant Office/Retail Space Available
$500 / Mo
13,622 SF

Multi-Tenant Office/Retail Space Available

Two-story office/retail space in The Knolls Center.

17993 Knl Ctr, Apple Valley, CA 92307
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Historic Apple Valley Inn Office
$1,800 / Mo
64,784 SF

Historic Apple Valley Inn Office

Unique office space in a historic landmark building.

20600 Suite 108 & 109, Apple Valley, CA 92307
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Versatile Space for Healthcare Providers
$1.00 SF/Yr
15,042 SF

Versatile Space for Healthcare Providers

Well-maintained 3,000 SF suite ideal for healthcare or professional offices.

18031 Suite, Apple Valley, CA 92307
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Apple Valley Office/Medical Space
Contact for pricing

Apple Valley Office/Medical Space

Premier office/medical building with great frontage in Apple Valley.

16008 Kamana Rd, Apple Valley, CA 92307
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Apple Valley Office Space Available
Contact for pricing
2,256 SF

Apple Valley Office Space Available

Newer office building with mountain views and tenant improvements.

16098 Kamana Rd, Apple Valley, CA 92307
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Medical Office Space Available
Contact for pricing

Medical Office Space Available

Medical office space for rent near St. Mary's Hospital.

15995 Tuscola 202, Apple Valley, CA 92307
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Multi-Tenant Office/Retail Space Available
Contact for pricing

Multi-Tenant Office/Retail Space Available

Two-story office/retail space in The Knolls Center available for rent.

17993 107, Apple Valley, CA 92307
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Multi-Tenant Office/Retail Space Available
Contact for pricing

Multi-Tenant Office/Retail Space Available

13,622 SF multi-tenant office/retail space on Highway 18.

17993 106, Apple Valley, CA 92307
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Medical Office Space Available
Contact for pricing
9,299 SF

Medical Office Space Available

Medical office space for lease near St. Mary's Hospital.

15995 Tuscola Rd, Apple Valley, CA 92307
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Medical Office Space Available
Contact for pricing
9,299 SF

Medical Office Space Available

Medical office space for lease near St. Mary's Hospital.

15995 Tuscola Rd, Apple Valley, CA 92307
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Apple Valley Medical Office Space
$27 SF/Yr
8,236 SF

Apple Valley Medical Office Space

Prime Medical Office, Apple Valley, CA

15099 Kamana Rd, Apple Valley, CA 92307
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Apple Valley Executive Office Suites
$12 SF/Yr
13,622 SF

Apple Valley Executive Office Suites

Prime Apple Valley office space, multiple suites available.

17993 Us Highway 18, Apple Valley, CA 92307
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Prime Apple Valley Medical Office
$15 SF/Yr
9,299 SF

Prime Apple Valley Medical Office

10-suite medical building, 1,075 SF vacant.

15995 Tuscola Rd, Apple Valley, CA 92307
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Medical Office Space Near Hospital
Contact for pricing

Medical Office Space Near Hospital

Medical office space near St Mary's Hospital in Apple Valley.

15995 Tuscola Rd, Apple Valley, CA 92307
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Visible Office Space on Highway
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Visible Office Space on Highway

Office space with open area, individual offices, and signage.

18930 Us Highway 18, Apple Valley, CA 92307
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Apple Valley Office Space for Sale
Contact for pricing
888 SF

Apple Valley Office Space for Sale

888 sq ft turnkey office, ideal for professionals.

17768 Wika Rd, Apple Valley, CA 92307
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Multi-Tenant Office/Retail Space Available
Contact for pricing

Multi-Tenant Office/Retail Space Available

Multi-tenant office/retail space available along Highway 18.

17993 Us Highway 18, Apple Valley, CA 92307
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Based on your search, we've compiled 33 Potential Opportunities for your consideration. Besides 24 Active listings in Apple Valley, CA, we suggest exploring alternatives. Consider Similar 9 Spaces for Sales.

Apple Valley, CA Office Properties & Spaces Leasing Opportunities Market Analysis

Explore Office Properties & Spaces leasing options in Apple Valley, CA with 33 listings featured on our commercial real estate exchange. The current inventory includes 4,130,272,080 square feet of properties with an estimated lease value of $74 SF/Yr.

Estimated lease rates for Office Properties & Spaces in Apple Valley, CA begin at $1.00 SF/Yr, with an average of $9 SF/Yr and extend to $27 SF/Yr.
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