Cayce, SC
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    Cayce, SC Office Buildings for Lease

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    West Columbia, SC Columbia, SC Lexington, SC
    Cayce Office/Medical Space Available
    $20 SF/Yr
    5,670 SF

    Cayce Office/Medical Space Available

    1105 State St, Cayce, SC

    5,670 SF building suitable for office or medical use.

    • Large fenced parking lot
    • Ideal for professional or medical office use
    • ±5,670 SF one‑story building
    • ADA accessible
    • Walking distance to Guignard Park, pharmacy, grocery store and restaurants
    Updated: Aug 8, 2025
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    Cayce Class A Office Space
    Contact for pricing
    5,555 SF

    Cayce Class A Office Space

    1300 12th St, Cayce, SC 29033

    Two-story office building with Class A space for rent.

    • Up to 5,555 square feet of Class A office space.
    • Convenient location with easy access to Columbia's Central Business District, Interstate 26, Columbia Metropolitan Airport, and the State Capitol Complex.
    • High‑speed internet connectivity with Cat 6 fiber optic cable availability.
    • Free parking adjacent to the building.
    • High‑traffic location on Knox Abbott Drive corridor (±28,000 vehicles per day).
    Updated: Mar 12
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    Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 2 Active listings in Cayce, SC, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 1 Properties for Sales.

    Office buildings for Lease in Nearby Cities

    Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

    Fully Leased Office Building
    Contact for pricing
    10,320 SF

    Fully Leased Office Building

    10,320 SF office building fully leased through 2030.

    1900-1906 Pineview, Columbia, SC
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    Office Space Near Golf Club
    $20 SF/Yr
    42,000 SF

    Office Space Near Golf Club

    Office building with convenient access and ample parking.

    101 Research Ct, Columbia, SC
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    Elgin Office Space For Lease
    Contact for pricing
    146,483 SF

    Elgin Office Space For Lease

    Office space available for lease in Elgin, South Carolina.

    501 Spears Creek Church Rd, Columbia, SC
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    Multi-Tenant Office Building in Columbia
    Contact for pricing
    41,519 SF

    Multi-Tenant Office Building in Columbia

    140,206 SF office building with suites available for rent.

    1600 Williams St, Columbia, SC 29201
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    Similar Spaces for Sale in Cayce, SC

    Consider Similar Space for Sale. We found 1 Spaces matching your search parameters.

    Office Building Near Downtown Columbia
    $685,000
    5,128 SF

    Office Building Near Downtown Columbia

    Office building with multiple suites, ideal for owner occupant.

    1202 Indigo Ave, Cayce, SC
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    Potential Development Sites for Consideration

    Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

    Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

    Commercial Land Build-to-Suit Opportunity
    $4,000/Mo
    2,400 SF

    Commercial Land Build-to-Suit Opportunity

    Commercial land available for build-to-suit in Jacksonville, NC.

    2683 Henderson Drive, Jacksonville, NC 28546
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    Prime Commercial Lot For Lease
    $7,500/Mo

    Prime Commercial Lot For Lease

    0.66 acre commercial lot in high-traffic area.

    Tift Avenue N, Tifton, GA 31794
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    Commercial Space on Trent Boulevard
    $1,200/Mo
    1,000 SF

    Commercial Space on Trent Boulevard

    Versatile commercial space ready for customization in a prime location.

    3709 Trent Road, New Bern, NC 28562
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    Cleared Lot in Williston
    Contact for pricing

    Cleared Lot in Williston

    C2-zoned lot in Williston's central business area for rent.

    33 NW 3RD St, Williston, FL 32696
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    Cayce, SC Office buildings Leasing Opportunities Market Analysis

    Explore Office buildings leasing options in Cayce, SC with 2 listings featured on our commercial real estate exchange. The current inventory includes 5,670 square feet of properties with an estimated lease value of $20 SF/Yr.

    Estimated lease rates for Office buildings in Cayce, SC begin at $20 SF/Yr, with an average of $20 SF/Yr and extend to $20 SF/Yr.
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