Earth City, MO Office buildings for Rent & Lease

Updated: Nov 22, 2025

Two-Story Office Building For Lease

100 Corporate Office Drive, Earth City, MO 63045

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128,512 sqft

Class A, 128,512 SF 2‑story office building with flexible open format layout.
New HVAC and new roof.
Ample parking with a 4+/1,000 ratio.
232 kV 3‑phase generator.
Raised floor data center.

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Updated: Feb 11, 2020

Four-Story Office Building Available

125 Corporate Office Dr, Earth City, MO

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72,000 sqft 7.58 AC lot

Full building availability with 141,423± RSF
High parking ratio: 7/1,000 RSF (including free structured parking)
Potential building and monument signage opportunities
Floors 1 & 4 available immediately
Vertical campus

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Turn a Listing Into an Investment Snapshot Cap Rate, Potential NOI, Demand score for every listing. Go To Analytics Center

Based on your search, we've compiled 10 Potential Opportunities for your consideration. Besides 2 Active listings in Earth City, MO, we suggest exploring alternatives. Consider Similar 4 Spaces in Nearby Cities, and Similar 4 Properties for Sales.

Office buildings for Lease in Nearby Cities

Here are 4 Similar Spaces we found in Nearby Locations for your consideration.

Suite 105 Office Suite

Saint Charles, MO 63301

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1,275 sqft

Full-service lease Suite 105 in a C-2 zoned, two-story multi-tenant office building with ample parking.

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Office Building with Generator Backup

2070 Little Hills Expy, Saint Charles, MO 63301

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41,125 sqft 4.75 AC lot

41,125 SF office building with generator, UPS back-up, IT rooms, and 269 parking spaces.

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Office Space with Furniture Included

13640-13690 Riverport Dr, Maryland Heights, MO 63043

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43,556 sqft

Previously used by a large engineering group, with most furniture and cubicles set to remain.

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Maryland Heights Office Building For Sale

2043 Woodland Pkwy, Maryland Heights, MO

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63,000 sqft 2.80 AC lot

Stabilized investment opportunity with recent renovations and highway access.

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Similar Spaces for Sale in Earth City, MO

Consider Similar Space for Sale. We found 4 Spaces matching your search parameters.

Institutional-Quality Office Building For Sale

3301 Rider Trail S, Earth City, MO 63045

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27,560 sqft

Office building in established suburban office and employment corridor.

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Renovated Office Building For Rent

3301-3303 Rider Trl S, Earth City, MO

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27,560 sqft 9.89 AC lot

Office building with renovated lobby and signage opportunities available for lease.

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Office Building at Signalized Corner

3330 Rider Trl, Earth City, MO 63045

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6,489 sqft 1.62 AC lot

Office property with redevelopment or owner-user potential at a signalized intersection in an industrial park.

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Office/Pharmaceutical/Manufacturing Building in Earth City

Earth City, MO 63044

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315,000 sqft

315,000 SF office/pharmaceutical/manufacturing building in St. Louis, MO.

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Earth City, MO Office buildings Lease Rates & Market Statistics

Explore 2 Office buildings for lease in Earth City, MO on Realmo, a commercial real estate exchange covering the Earth City area. The current inventory totals 200,512 square feet of properties.

Earth City accounts for 3% of the 72 office buildings currently available across St. Louis County, where nearby markets include Saint Louis and Chesterfield. Office buildings are one of the more limited space types in Earth City, with just 2 listings currently available — a scarcity worth factoring into lease negotiations. Also worth a look for tenants weighing alternatives: Office Units (8 listings) elsewhere in the Earth City market.