Greenwood, SC Mixed-use properties for sale

Versatile Commercial Building, Greenwood SC

$159,000

1,722 SF

Versatile Commercial Building, Greenwood SC

1601 E Cambridge Ave, Greenwood, SC 29646

Adaptable commercial building with high visibility and flexible build-out options.

High‑visibility corner location with strong road presence
Large, open interior with high ceilings and exposed framing, ideal for customization
Flexible build‑out options suitable for retail, light industrial, workshop, studio, storage, or office conversion
Generous lot space for parking, storage, or expansion
Durable block construction

Updated: Feb 3

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Historic Uptown Greenwood Commercial Property

$749,000

4,684 SF

Historic Uptown Greenwood Commercial Property

206 Main St, Greenwood, SC 29649

Versatile commercial space in a vibrant historic district with unique features.

Prime Location: Situated in the heart of Uptown Greenwood with high visibility and foot traffic.
Versatile Space: Just under 5,000 sqft with a flexible layout suitable for retail, office, or mixed‑use purposes. Includes seven private office suites, a shared kitchenette, and a large basement.
Historic Charm: Features original hardwood floors, ghost murals (including a vintage Coca‑Cola mural), and architectural details reflecting its 1917 origins.
Ample Parking: Benefits from an expansive city‑owned front lot providing abundant parking.
Turnkey Opportunity: Includes all remaining furnishings upstairs, making it ready for a new business/owner.

Updated: Sep 9, 2025

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$479,000

4,753 SF

Iconic Mixed-Use Property, Greenwood SC

Mixed-use property in vibrant Uptown Greenwood, ideal for live/work.

204 Main St, Greenwood, SC 29649

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Explore Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

$175,000

0.88 Acres

Laurens Mixed-Use Metal Building

Near-acre lot, versatile metal building.

2555 Neely Ferry Rd, Laurens, SC 29360

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$299,900

0.06 Acres

Downtown Laurens Mixed-Use Gem

Historic building, high traffic area, multiple uses

111 Public Sq, Laurens, SC 29360

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Edgefield Mixed-Use Investment Opportunity

$1,490,000

20,824 SF

Edgefield Mixed-Use Investment Opportunity

Mixed-use property with retail and apartments in historic Edgefield, SC.

112 Courthouse Sq, Edgefield, SC 29824

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Mixed-Use Property in Historic Edgefield

$1,490,000

20,824 SF

Mixed-Use Property in Historic Edgefield

Investment opportunity with storefronts, apartments, and ample parking.

112 Courthouse Sq, Edgefield, SC 29824

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

Greenwood Commercial Corner Lot Opportunity

$174,000

0.54 Acres

Greenwood Commercial Corner Lot Opportunity

Prime commercial corner lot in Greenwood's active corridor.

441/433 Calhoun Ave, Greenwood, SC 29649

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Explore Off-Market Properties in Greenwood, SC

Consider similar Off-Market properties in Greenwood, SC. You may contact the owners directly to inquire about their potential intentions to sell. To help you make a strong first impression, we can assist by reaching out to these owners with compelling proposals created using our AI tool.

1610 Calhoun Rd

STORE/OFFICE (MIXED USE) • 12,000 SF

Value Estimation

$645,000

1610 Calhoun Rd, Greenwood, SC 29649-8907

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430 Cobb Rd

STORE/OFFICE (MIXED USE) • 4,126 SF

Value Estimation by Request

430 Cobb Rd, Greenwood, SC 29649-9002

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213 Anderson Cir

STORE/OFFICE (MIXED USE) • 2,244 SF

Value Estimation by Request

213 Anderson Cir, Greenwood, SC 29649-8908

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231 Hampton Ave Ste H

STORE/OFFICE (MIXED USE) • 3,445 SF

Value Estimation by Request

231 Hampton Ave Ste H, Greenwood, SC 29646-2299

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327 Main St, Unit 2

STORE/OFFICE (MIXED USE) • 661 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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805 Montague Ave

STORE/OFFICE (MIXED USE) • 13,660 SF

Value Estimation

$1,645,000

805 Montague Ave, Greenwood, SC 29649-1471

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328 Main St

STORE/OFFICE (MIXED USE) • 8,149 SF

Value Estimation

$540,000

328 Main St, Greenwood, SC 29646-2797

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327 Main St

STORE/OFFICE (MIXED USE) • 2,523 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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418 Main St

STORE/OFFICE (MIXED USE) • 5,190 SF

Value Estimation by Request

418 Main St, Greenwood, SC 29646-2756

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2432-C Hwy 293rd E

STORE/OFFICE (MIXED USE) • 2,940 SF

Value Estimation by Request

2432-C Hwy 293rd E, Greenwood, SC 29649

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682 Byp 72nd NW

STORE/OFFICE (MIXED USE) • 4,186 SF

Value Estimation by Request

682 Byp 72nd NW, Greenwood, SC 29649

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1303 Montague Ave Ext

STORE/OFFICE (MIXED USE) • 5,824 SF

Value Estimation

$525,000

1303 Montague Ave Ext, Greenwood, SC 29649-9028

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106 Byp 225

STORE/OFFICE (MIXED USE) • 11,507 SF

Value Estimation

$1,170,000

106 Byp 225, Greenwood, SC 29646-1154

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529 Byp 72nd NW

STORE/OFFICE (MIXED USE) • 8,605 SF

Value Estimation

$970,000

529 Byp 72nd NW, Greenwood, SC 29649-1355

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314 Main St

STORE/OFFICE (MIXED USE) • 10,076 SF

Value Estimation by Request

314 Main St, Greenwood, SC 29646-2758

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327 Main St, Unit 5

STORE/OFFICE (MIXED USE) • 651 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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327 Main St, Unit 6

STORE/OFFICE (MIXED USE) • 651 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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300 Montague Ave

STORE/OFFICE (MIXED USE) • 11,766 SF

Value Estimation by Request

300 Montague Ave, Greenwood, SC 29649-1938

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327 Main St, Unit 3

STORE/OFFICE (MIXED USE) • 651 SF

Value Estimation by Request

327 Main St, Greenwood, SC 29646-1601

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1732 By-Pass 72

Mixed-use properties • 20,884 SF

Value Estimation by Request

1732 By-Pass 72, Greenwood, SC 29649

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104 Maxwell Ave

STORE/OFFICE (MIXED USE) • 70,979 SF

Value Estimation

$2,980,000

104 Maxwell Ave, Greenwood, SC 29646-2641

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Greenwood, SC Mixed-Use Properties Investment Opportunities Market Analysis

Explore 34 mixed-use properties for sale in Greenwood, SC, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 311,019 square feet of properties for sale, with an estimated market value of $8,323,000.

Sale prices for multi use buildings in Greenwood, SC start at $159,000, averaging $924,777, and reaching up to $2,670,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Greenwood, SC Mixed-use Properties for Sale

Versatile Commercial Building, Greenwood SC

Adaptable commercial building with high visibility and flexible build-out options.