Rio Grande City, TX Medical Office Space for sale

$825,000

8,300 SF

Medical Office and Retail Building

5448 E US Highway 83, Rio Grande City, TX 78582

Multi-office building with flexible space for medical or retail uses on prime highway-adjacent property.

Santa Cruz Medical Plaza with approx. 8,300 total SF and four office spaces ready for medical, retail, and more
Four office suites available: 1,461 SF, 1,500 SF, 1,540 SF, and 3,138 SF
Central heating and central air conditioning
Metal roof and stucco construction
Covered parking and special needs parking available

Updated: Jun 6

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$2,200,000

15,750 SF

Medical Plaza Investment Opportunity

5322 E. US Hwy 83, Rio Grande City, TX 78582

Medical plaza for sale in Rio Grande City, Texas.

Dedicated medical plaza ideal for healthcare businesses.
Approximately 15,750 SF of space, suitable for various medical or office uses.
Sits on 1.11 acres, potentially allowing for expansion.
Strategic location in Rio Grande City.
Located in a high‑traffic area near Payne Dealership, City Offices, Holiday Inn Express, Exxon Mobil, Family Dollar Store & Tejano Mart.

Updated: Mar 6

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$339,900

3,752 SF

Mixed-Use Property in Rio Grande

Two buildings suitable for office and retail in Rio Grande.

115 N Britton Avenue, Rio Grande City, TX 78582

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Based on your search, we've compiled 11 Potential Opportunities for your consideration. Besides 3 Active listings in Rio Grande City, TX, we suggest exploring several alternatives: 4 properties in Nearby Cities, plus 4 Land Listings that present a potential for development.

Opportunities in Nearby Cities

Here are 4 Similar properties we found in Nearby Locations for your consideration.

$2,995,000

7.15 Acres

Prime Commercial Tract on Ware

7+/- acre commercial tract in McAllen's high-growth corridor.

S Ware Road, Mcallen, TX 78504

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$650,000

2,400 SF

Medical Office Suite with Lobby

Medical-ready office suite with lobby, reception, exam or work rooms, and multiple support areas.

1022 E Griffin Parkway Unit #104 B, Mission, TX 78572

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$650,000

2,400 SF

Medical Office Building with Lobby

Medical office space with reception, multiple exam or work rooms, and ample parking in Mission.

1022 E Griffin Parkway # B ##104 B, Mission, TX 78572

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McAllen Assisted Living Conversion Opportunity

$950,000

8,040 SF

McAllen Assisted Living Conversion Opportunity

8,040 SF McAllen building suitable for various commercial uses.

4513 W US Highway 83, Mcallen, TX 78501

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Potential Development Sites for Consideration

Can't find the perfect fit? These Land listings present an alternative path: the potential to develop a property for your specific goals.

Important: These AI-suggestions are a starting point, not a guarantee of permitted use. All zoning, permitting, and land use information must be independently verified by you with the appropriate local authorities before making any commitments.

$1,300,000

0.95 Acres

Prime Commercial Lot in McAllen

Vacant commercial lot with high visibility and traffic exposure.

4029 Expressway 83, Mcallen, TX 78501

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$6,250,000

15.48 Acres

Prime Development Land For Sale

15.48 acres of land suitable for various development projects.

6801 Saratoga, Corpus Christi, TX 78414

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$1,945,000

3.00 Acres

Prime Commercial Lot Available

Over 3-acre commercial lot at a busy intersection.

7151 Williams DR, Corpus Christi, TX 78412

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$419,885

5.93 Acres

Land

Commercial land · 5.93 Acres

2778 FM 236, Victoria, TX 77905

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Rio Grande City, TX Medical Office Space Market Trends and Statistics

Explore 3 medical office space for sale in Rio Grande City, TX, showcased through 3 active listings on our real estate platform. These investment opportunities span a total of 27,802 square feet of properties for sale, with an estimated market value of $3,364,900.

Sale prices for medical spaces in Rio Grande City, TX start at $339,900, averaging $1,121,633, and reaching up to $2,200,000 — offering options for a variety of budgets and business needs. Daily updated analytics ensure you stay ahead with the latest data and market trends.

Neighborhood	Average Price
78582	$1.1M

Neighborhood

Average Price

78582

$1.1M

Rio Grande City, TX Medical Office Space for Sale

5448 E US Highway 83, Rio Grande City, TX 78582

5322 E. US Hwy 83, Rio Grande City, TX 78582

115 N Britton Avenue, Rio Grande City, TX 78582